Vol 5, No 4 (2008)
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AN EDITORIAL ARTICLE
6-7 414
Abstract
Istanbul (Turkey) hosted the 3rd European Congress of Pediatricians - EUROPAEDIATRICS-2008 on June 14-17, 2008.
VACCINATION
20-24 416
Abstract
In this article, the authors demonstrate high spread of the human papilloma viral contamination and danger, which this virus poses for the health of population. Taking into account that this is the only virus, for which it is proved that there are properties for inducing the neoplastic process in the human body, the interest revealed by the scientists from all over the world towards the creation of a specific vaccine is beyond any doubt. The researchers showed the results of application of the primary vaccine prevention for papilloma viral infection abroad. They have also highlighted their own experience in vaccination, which is probably most valuable for the pediatricians, who understand the reality of a danger and attempt to avert it.
Key words: human papilloma virus, prevalence, papillomatosis, oncogenous properties, prevention.
Key words: human papilloma virus, prevalence, papillomatosis, oncogenous properties, prevention.
9-13 403
Abstract
We are presenting one of the chapters from the who report devoted to critical emergencies of international importance in the public healthcare, the most frightful of which is still pandemic flu. The counter measures in respect of the given threat are preemptive. They give a chance to get ready for the pandemic and probably prevent the threat from coming true.
Key words: influenza pandemic, bird flu, prevention, who global strategy.
Key words: influenza pandemic, bird flu, prevention, who global strategy.
25-27 414
Abstract
The article considers acute otitis media, which is acknowledged to be rather an urgent issue of pediatrics and particularly of infancy. The authors highlight the major aspects of the etiology and pathogenesis, diagnostics and clinical run of the given pathology. They stress difficulty of otitises treatment: antibacterial therapy justification and in the event of its application — high probability of the pathogen antibiotic resistance. Therefore, otitises vaccine prevention becomes quite perspective, which is convincingly demonstrated by the example of the conjugated vaccine against the pneumococcal infection, most often leading to the complicated otitises.
Key words: acute otitis media, clinical course, diagnostics, treatment, vaccine prevention, children.
Key words: acute otitis media, clinical course, diagnostics, treatment, vaccine prevention, children.
14-19 623
Abstract
The review highlights data on the influenza pandemic in 1918, 1957, 1968, 1977 and virus strain properties, which caused them. The author considers genesis mechanisms of the pandemic flu strains, including mutations, resulting into the increase of virulence, as well as an opportunity for the process of the human and bird flu reas sortion to take part in the genesis of the pandemic strains. The author also examines the mechanisms for turning low virulent flu viruses into high virulent ones able to induce epizootic outbreaks. The work discusses genes and proteins, defining specific character of the avian flu viruses and probable H5N1 flu pandemic appearance. The author thinks it quite unlikely for such an event to occur.
Key words: flu, pandemic.
Key words: flu, pandemic.
CASE REPORT
119-122 415
Abstract
The reason for atopic dermatitis in the majority of children under one year is known to be cow milk allergy. The only possibility to eliminate the dermatitis development among infants with the pathology and to assure healthy growth is to provide nutritional management with amino acid mix. The authors present a clinical case of the efficient application of such mix (Neocate), which is an adopted infant milk formula, enriched with a necessary complex of all nutrients, microelements and vitamins.
Key words: cow milk allergy, nutritional management, children.
Key words: cow milk allergy, nutritional management, children.
123-125 437
Abstract
The article provides the results of montelukast efficiency depending on bronchial asthma severity level and the duration of a disease; the assessment of functional figures dynamics, disease pattern before and after the treatment with montelukast and the possibility of its application as mono therapy to achieve long term disease remission and asthma symptoms control.
Key words: bronchial asthma, montelukast, children.
Key words: bronchial asthma, montelukast, children.
GENETICS IN PEDIATRICS
31-37 1065
Abstract
The article overviews the results of the studies of the genetic foundations of predisposition to the bronchial asthma. The authors provide detailed information on the molecular and genetic mechanisms of the bronchial asthma, roles performed by the polymorphisms of the interleukin genes and their receptors, IgE receptors, adrenergic receptors, CYS-LT enzymes in the pathogenesis of this disease, as well as their impact on the effectiveness of the drug therapy.
Key words: bronchial asthma, genetic predisposition, pharmacogenetics.
Key words: bronchial asthma, genetic predisposition, pharmacogenetics.
PHARMACOECONOMICS IN PEDIATRICS
38-44 383
Abstract
In the given article, the authors discuss the most difficult issue of the pediatrics, which is the treatment of the severe bronchial asthma. Our columnist is professor A.S. Kolbin introduces omalizumab, a new medication from the monoclonal antibodies group, to our readers. It allows practitioners to control the severe persistent bronchial asthma. The article accentuates the clinical effectiveness and pharmacoeconomic aspects of the medication application.
Key words: bronchial asthma, severe run, treatment, monoclonal antibodies, children.
Key words: bronchial asthma, severe run, treatment, monoclonal antibodies, children.
REPRODUCTIVE HEALTH OF CHILDREN AND TEENAGERS
45-53 731
Abstract
The review is dedicated to the problem of hypogonadotropic hypogonadism. Modern ideas of the stages of normal sexual development of girls, etiology and pathogenesis of constitutional arrest of sexual development and hypogonadotropic hypogonadism are presented. Modern approaches to the treatment of this condition using hormone replacement therapy and non-hormonal agents are considered.
Key words: hypogonadotropic hypogonadism, sexual development arrest, treatment, hormone replacement therapy.
Key words: hypogonadotropic hypogonadism, sexual development arrest, treatment, hormone replacement therapy.
ORIGINAL ARTICLES
54-56 398
Abstract
The authors studied the results of immunization among the children against the infection caused by haemophilus influenzae type B by two vaccines: ACT HIB and Hiberix. They confirmed high vaccination efficiency, as among almost all the children they identified an increase of the antibody titer against type b haemophilus influenzae. Vaccine tolerance was good. Side effects were rare (brief body temperature increase, focal reactions) and ill defined.
Key words: haemophilus influenzae type B, vaccination, children.
Key words: haemophilus influenzae type B, vaccination, children.
58-64 613
Abstract
Premature newborns are a high risk group in terms of the infection complications growth. therefore, it is highly urgent to choose the efficient and safe antibacterial medications for the given category of patients. The authors carried out a pharma coepidemiological study of the carbapenems application among 353 newborns with very low body weight at birth, as well as the literature analysis on the use of this medications group in compliance with the evidence based medicine. As a result, they showed that for the last 8 years the frequency of the carbapenems application in Saint-Petersburg among the newborns has grown from 10 to 52%. It is statistically accurate that imipenem/cilastatin was more often used to the amount of 25 mg/kg twice a day. In 71% of cases, carbapenems were applied in the form of the empiric therapy against the general bacterial infection in combination with vancomycin and/or metronidazole. Antibiotics proved to be safe. The literature analysis showed that there is no data, which would allow one to compare the efficiency of carbapenems with other antibiotics among the newborns based on the results of the meta analyses and randomized clinical studies. Nowadays, carbapenems demonstrated high efficiency and safety in the small clinical observations.
Key words: carbapenems, imipenem, meropenem, newborns with very low body weight at birth.
Key words: carbapenems, imipenem, meropenem, newborns with very low body weight at birth.
65-69 455
Abstract
The article highlights the results of the survey carried out among the parents of the children, who attend preschool education institutions (PEI) in Krasnodar and PEI employees, who are involved in the evaluation of the children's health and rehabilitation process. The authors defined a social portrait of the families whose children attend municipal PEIS. They identified that most parents are rather well aware of the medical issues. Acute sick rate of the preschool age is high, as about 15% of children have already acquired a chronic pathology in the form of a confirmed diagnosis. The authors also established a dependence of the sick rate among the preschool children on the age, at which they were enrolled to the PEI and living conditions. All the parents are worried about the health of their children and would like to enhance it. Most respondents believe that PEI preventive programs should be financed by the government.
Key words: preschool children, health status, preventive medical care, public opinion poll.
Key words: preschool children, health status, preventive medical care, public opinion poll.
70-75 504
Abstract
The article is devoted to the combined pathology in childhood, namely a combination of bronchial asthma and gastroesophageal reflux disease. The authors highlighted the key theories of the disease etiopathogenesis under alternating environmental conditions. They also highlighted the results of their own studies.
Key words: bronchial asthma, gastroesophageal reflux disease, children.
Key words: bronchial asthma, gastroesophageal reflux disease, children.
76-80 583
Abstract
There has been noted a significant growth of spread of behavior reactions fraught with health risks among children lately. Peculiarities of behavior stereotypes among children may be a considerable factor, determining functional disorders at first and subsequently more serious pathology conditions. This determined the relevance of large scale complex research on health conditions among teenagers of Ivanovo city and Ivanovo region. The research included the study of school children morbidity, determination of the role of behavior stereotypes in forming of digestive tract pathology, elaboration of possible measures for improvement of cases on gastrointestinal tract diseases.
Key words: feeding analysis, addictive behavior, teenage morbidity, forming of digestive tract pathology.
Key words: feeding analysis, addictive behavior, teenage morbidity, forming of digestive tract pathology.
CLINICAL RECOMMENDATIONS
For Pediatricians' Practice
88-92 401
Abstract
The article provides the data on the new application and effectiveness aspects of the probiotics from the viewpoint of the evidence based medicine. It demonstrated the decrease of the chronic nasopharynx pathology backsets in the event of probiotic prescriptions. The authors highlight the results of the research, in which the given medications were successful applied to prevent the antibiotic associated diarrhea among the children, suffering from the respiratory diseases.
Key words: probiotics, lactobacillus, bifidobakterium, intestinal dysbiosis, children.
Key words: probiotics, lactobacillus, bifidobakterium, intestinal dysbiosis, children.
94-97 406
Abstract
The authors review the pathogenesis of the come done and its treatment methods. They provide the data on the high effectiveness of the combined therapy by the topical medications: adapalene and benzoyl peroxide in the event of come done among the teenagers.
Key words: acne, local treatment, children.
Key words: acne, local treatment, children.
98-103 519
Abstract
The article highlights the results of the long term observations over the children, residing in the republic of Bashkortostan and suffering from cystic fibrosis. They particularly dwells on the arrangement of the comprehensive diagnostics, first results of the neonatal screening, peculiar properties of the clinical presentation, issues of the medicated support and social rehabilitation at the republican center of cystic fibrosis.
Key words: cystic fibrosis, treatment, social rehabilitation, children, teenagers.
Key words: cystic fibrosis, treatment, social rehabilitation, children, teenagers.
104-111 429
Abstract
In the article, the author considers the clinical effects of preandprobiotics in formulas for the artificial feeding from the viewpoint of the evidence based medicine, their effect on the gut and immune system.
Key words: immune nutrients, artificial feeding, children.
Key words: immune nutrients, artificial feeding, children.
112-114 448
Abstract
The given article highlights an important aspect of the acute enteric infections among the infants — application of the enterosorbents. Noteworthy to say that the latter takes part not only in the egestion of the endo and exotoxins from the human organism but also in the elimination of a causative agent. The authors convincingly showed an advantage of medications from this group in the treatment, as they drastically reduced the relief terms for the disease symptoms and patients recovery.
Key words: acute enteric infections, rotaviral infection, treatment, enterosorbents, children.
Key words: acute enteric infections, rotaviral infection, treatment, enterosorbents, children.
115-118 623
Abstract
The authors described the experience of the topical glucocorticoid mometasone application among children with photoder matoses (solar burns, photocontact dermatitis). They came to conclusion that the medication was highly efficient and well tolerable.
Key words: photodermatoses, treatment, mometasone, children.
Key words: photodermatoses, treatment, mometasone, children.
FROM THE UNION OF PEDIATRICIANS OF RUSSIA
126 616
Abstract
RESULTS OF THE PEDIATRICIANS SURVEY AT THE XIIth CONGRESS OF THE RUSSIAN PEDIATRICIANS
TRAINING FOR TRAINERS — EDUCATIONAL PROGRAM FOR PARENTS
128-132 367
Abstract
The authors consider the symptomatic therapy of acute respiratory diseases among children. They also discuss the application efficiency and safety of the local vasoconstrictors (decongestants).
Key words: acute respiratory diseases, symptomatic therapy, decongestants, children.
Key words: acute respiratory diseases, symptomatic therapy, decongestants, children.
ISSN 1727-5776 (Print)
ISSN 2500-3089 (Online)
ISSN 2500-3089 (Online)
