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Central Pontine Myelinolysis in a Child: Clinical Case

https://doi.org/10.15690/pf.v18i6.2344

Abstract

Background. Central pontine myelinolysis (CPM) is limited symmetric non-inflammatory demyelination in the middle part of pontine. This disease is based on electrolyte balance disorders. Although CPM was firstly described in adults, but it can also occur in children. Every new case of CPM in children has undeniable interest and high scientific and practical significance due to its low incidence. Clinical case description. The child, 7 years old, had acute development, lethargy, multiple vomiting, subfebrile fever, pains in epigastric region. It has happened after drinking an unknown herb growing in the yard and previously covered with the insecticide "Akarin", according to the mother. The child was hospitalized in the pediatric department at the place of residence. The patient developed strabismus, swallowing disorder, and muscle weakness on infusion therapy. Biochemical blood test has shown hypokalemia and hyponatremia. Head MRI has shown symmetrical focal lesion of heterogeneous structure in pontine. Conclusion. Distinctive feature of this case is the development of CPM in a child on the ongoing therapy of hypokalemia and hyponatremia. The timely provision of qualified medical care has favoured the child's recovery.

About the Authors

Nailya F. Akhmetgaleeva
Children's Center of Psychoneurology and Epileptology of the Republican Children's Clinical Hospital
Russian Federation

Nailya F. Akhmetgaleeva, MD. eLibrary SPIN: 7926-0260

10 Tihoreсkaya Str., 450106, Ufa


Disclosure of interest:

Not declared



El’vira M. Yausheva
Children's Center of Psychoneurology and Epileptology of the Republican Children's Clinical Hospital
Russian Federation

El`vira M. Yausheva, MD

10 Tihoreсkaya Str., 450106, Ufa


Disclosure of interest:

Not declared



Klara Z. Bahtiyarova
Bashkir State Medical University
Russian Federation

Klara Z. Bahtiyarova, MD, PhD, Professor

3 Lenina Str., 450008, Ufa


Disclosure of interest:

Not declared



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Review

For citations:


Akhmetgaleeva N.F., Yausheva E.M., Bahtiyarova K.Z. Central Pontine Myelinolysis in a Child: Clinical Case. Pediatric pharmacology. 2021;18(6):492-497. (In Russ.) https://doi.org/10.15690/pf.v18i6.2344

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ISSN 1727-5776 (Print)
ISSN 2500-3089 (Online)