Vol 5, No 5 (2008)
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AN EDITORIAL ARTICLE
VACCINATION
10-12 464
Abstract
This article takes up the issue of carrying hemophilic bacteria infections. It represents a wide range of diseases whose etiological factor is haemophilus influenzae. The only dependable means of specific prophylaxis is the active immunization. Based on their experience of vaccine application, the authors demonstrate the safety and efficiency of the applied vaccine and give recommendations to optimize infant vaccination.
Key words: hemophilic infection, vaccination, infants.
Key words: hemophilic infection, vaccination, infants.
14-17 634
Abstract
The article is dedicated to the papilloma virus infection. As it became known in October 2008, the nobel prize in the field of medicine and physiology this year is awarded to the German doctor of Harald Zur Hausen who has proved the role of the human papilloma virus as causative factor of the cervical carcinoma. This is epoch making discovery because of human papilloma virus is most frequent of sexually transmitted infections. The authors demonstrated the high HPV prevalence. One of the most frequent manifestations of this infection is in more details presented pointed condy loma, clinical course of the disease and differential diagnostics of its various forms. Considering treatment inefficiency, the authors convincingly demonstrate that the only opportunity available to keep a human from the illness development is a specific immune prevention.
Key words: papillomavirus infection, pointed condylomas, precancers, prevention.
Key words: papillomavirus infection, pointed condylomas, precancers, prevention.
25-29 505
Abstract
The authors have analyzed the studies of the mechanism of action of a new immunomodulator — pidotimod. They also howed the differently directed actions of the immunomodulator on the innate and adaptive immunity. Based on the previous fundamental studies, researchers proposed a new concept of molecular and cellular mechanisms of action of pidotimod. They presented the results of the international studies of the pidotimod preventive and therapeutic efficiency in the children with the recurrent respiratory infections.
Key words: immunomodulator, acute respiratory infections, children.
Key words: immunomodulator, acute respiratory infections, children.
18-22 434
Abstract
The vaccination against pneumococcal infection during the preparation for a probable flu pandemic has recently been given a significant role. The authors found out that the attachment of the secondary bacterial infection is an important cause for the morbidity and mortality during the flu pandemic. The pneumococcus has been acknowledged to be the main causative agent, causing up to 50% of the secondary bacterial pneumonias during the flu pandemic. The interepidemic period and pandemic prevention period are the ideal time to carry out preventive actions, as the full scale pneumococcal vaccination is not feasible when the flu pandemic breaks out.
Key words: flu pandemic, pneumococcal infection, vaccination, children.
Key words: flu pandemic, pneumococcal infection, vaccination, children.
CASE REPORT
124-126 543
Abstract
This article demonstrates the results of the scientific research, whose purpose was to study the impact of cetirizine syrup on the course of atopic eczema among 36 children (2–6 years old). The study shows that introduction of the medication in the complex therapy of atopic eczema in children provides a fast clinical effect. Cetirizine syrup is well tolerated by the children.
Key words: atopic eczema, children, treatment.
Key words: atopic eczema, children, treatment.
GENETICS IN PEDIATRICS
Yu.S. Akoev,
A.V. Migali,
N.V. Zhurkova,
O.B. Kondakova,
E.A. Roslavtseva,
A.R. Pinaeva,
V.A. Skvortsova,
I.I. Migali
31-33 1795
Abstract
The article highlights the medical case of a rare hereditary disease — glycosylation disorder syndrome type 1b, unique for our country. This syndrome is referred to the heterogeneous group of the congenital diseases characterized by the disorder of glycoprotein synthesis as a result of the defects N or O glycosylation. Manifestations of the disease are protein losing enteropathy and severe developmental delay, hypoglycemia, co agulopathy (thrombosis), liver injury. glycosylation disorder syndrome type 1b differs from other types of this group absence of the neurologic semiology and efficiency of therapy by mannose.
Key words: glycoproteins, glycosylation disorders, manifestations, mannose, children.
Key words: glycoproteins, glycosylation disorders, manifestations, mannose, children.
REPRODUCTIVE HEALTH OF CHILDREN AND TEENAGERS
34-37 429
Abstract
This article touches upon the most topical problem of the modern medicine — treating pregnant patients, particularly those suffering from bronchial asthma and allergic rhinitis. Based on a number of case studies, the authors argue the need for the continuation of treatment during pregnancy in order to gain and maintain control over the diseases. The risk of complications and their range are significantly higher in case of non controlled course of bronchial asthma vs. that under an adequate therapy. The article gives the basic provisions to treat the said category of patients.
Key words: bronchial asthma, allergic rhinitis, treatment, risk factors, pregnancy.
Key words: bronchial asthma, allergic rhinitis, treatment, risk factors, pregnancy.
ORIGINAL ARTICLES
38-42 406
Abstract
The authors studied the efficiency of the 3 months long therapy by Rabeprazole after eradication of the causative agent in the children with h. pylori associated gastritis from the high risk group of the development post helicobacter gastritis. They demonstrated that most children with h. pylori associated gastritis, who have un favourable prognostic factors, have persistence of the inflammatory infiltrate in the mucosa of the antral stomach after eradication, which is accompanied with the elevated secretion of the hydrochloric acid and development of the acid dependent diseases. The use of the anti secretory medications during 3 months after h. pylori eradication among these children allows one to prevent the development of the gastritis and its complications.
Key words: h. pylori_associated gastritis, eradication of h. Pylori, children, rabeprazole.
Key words: h. pylori_associated gastritis, eradication of h. Pylori, children, rabeprazole.
43-47 464
Abstract
In the article, the authors discuss the local treatment of atopic eczema. They give data from the series of clinical studies on the application of non steroid medication in the children — calcineurin blocker pimecrolimus. This group is specifically essential in the event of the sensitive skin areas injury, where the skin absorptive capability and side effects development probability are the highest during the long term application of the topic glucocorticosteroids. The authors present to colleagues the first results of their experience in treatment of the children with atopic eczema.
Key words: atopic eczema, treatment, calcineurin blockers, pimecrolimus, children.
Key words: atopic eczema, treatment, calcineurin blockers, pimecrolimus, children.
48-51 448
Abstract
Through the indirect degranulation of mast cells, anaphylaxis test, solid phase immune enzyme analysis, the researchers evaluated the immuno biological features of serum of 20 patients suffering from atopic mild and moderate bronchial asthma with domestic sensitization. All received water salt extracts of insects (cockroach, black beetle, American cock roach, ash gray cockroach, cricket, fly, moth, mealworm, weevil, billbug) demonstrated specific activity. An immune enzyme analysis has revealed more intensive allergic features of substances extracted from black beetle, cockroach, fly and moth.
Key words: insect allergens, allergen specific immunotherapy, immuno biological features of allergic extracts, Ige anti bodies.
Key words: insect allergens, allergen specific immunotherapy, immuno biological features of allergic extracts, Ige anti bodies.
52-56 742
Abstract
In the given article, the authors highlight the results of the research into the school dysadaptation of the children, who have undergone intracranial vascular injuries in neonatal period. Researchers also studied the efficiency of atomoxetine for the correction of this pathology. The authors demonstrated both its high efficiency and good tolerance and safety in the event of the attention deficiency and hyperactivity disorder.
Key words: school dysadaptation, attention_deficit and hyper activity disorder, treatment, children.
Key words: school dysadaptation, attention_deficit and hyper activity disorder, treatment, children.
57-59 488
Abstract
The comparison of quality of the images at various stages complex dynamic nephroscintigraphy of the urinary tract received with use of various types of radiotracers. To all patients has been executed dynamic nephroscintigraphy with orthostatic sign and indirect radionuclide cystography, also the analysis of quality of images is lead by a method of expert estimations. It was established, that the best opportunities of a visual estimation of a condition of collective system of kidneys and ureters are provided with application tubular radiotraceres, and for an estimation parenchymatous phases of research — glomerular traceres.
Key words: vesicoureteral reflux, secretory function of kidneys, excretory function of kidneys, dinamic scintigraphy, radionuclide cystography.
Key words: vesicoureteral reflux, secretory function of kidneys, excretory function of kidneys, dinamic scintigraphy, radionuclide cystography.
L.T. Faizova,
V.V. Alatyrtsev,
G.F. Gordeeva,
I.V. D'yachenko,
E. Jargal,
M.I. Bakanov,
M.Ya. Studenikin,
A.N. Tsygin
60-63 559
Abstract
The authors presented the data on the homo cysteine serum concentration in the children with nephrotic syndrome. They established the high rate of hyper homo cysteinemia in the nephritic syndrome, but the degree of the homocysteine concentration increase is largely due to the kidney's functional status rather than the activity of the disease. They also discuss the pathogenetic role of hyper homo cysteinemia in the event of the chronic nephritic pathology.
Key words: homo cysteine, nephrotic syndrome, children.
Key words: homo cysteine, nephrotic syndrome, children.
64-68 470
Abstract
This article considers the basic principles of a rational antibacterial therapy. The authors give a more detailed data on randomized controlled studies of azitromicine application (macrolide group) in case of upper airways respiratory infections of children. The findings demonstrate the effectiveness and safety of the medication, which allows practitioners to safely apply it for the treatment of the said pathology among children.
Key words: azitromicine, upper airways respiratory infections, tonsillitis, otitis, sinusitis, children.
Key words: azitromicine, upper airways respiratory infections, tonsillitis, otitis, sinusitis, children.
69-73 719
Abstract
Sleep is an important factor in the live of children and it is a vital need, essential for a child's health and growth. Children who get enough sleep are more likely to function better and they are less prone to behavioral problems and moodiness. Sleep apnea is one of the causes of sleep disorders among the children. Undiagnosed and untreated sleep apnea may contribute to daytime sleepiness and behavioral problems including difficulties at school. Сhildren are also more likely to be hyperactive and have difficulty paying attention. The polysomnography is the precise registration of the architecture and microstructure of sleep. This information allows clinicians to evaluate any apparent fluctuations in breathing, heart rate changes, or oxygen desaturations within the context of sleep physiology.
Key words: sleep, sleep disorder, sleep apnea, polysomnography, children.
Key words: sleep, sleep disorder, sleep apnea, polysomnography, children.
74-78 451
Abstract
The article presents the results of the investigation of indices of power density spectrums of EEG in healthy and in patients with bronchial asthma in condition of physiological rest and negative emotional activation. The findings of this research about the disorganization of electrobiological activity of brain in patients with bronchial asthma show on the increased tonic activation of the brain controlling systems during this disease.
Key words: bronchial asthma, EEG, emotional activation, power density spectrum, children.
Key words: bronchial asthma, EEG, emotional activation, power density spectrum, children.
NUTRITION AND IMMUNITY
79-87 680
Abstract
The article highlights the key issues of the classical immunology, modern definition of the immunity and immunologic tolerance, mechanisms of the specific and adaptive immune responses. Based on the data of the new scientific research, the authors showed peculiarities in the development of the immune system and anti contagious immune response in ontogenesis, the role of the breast feeding in the formation of an adequate immune response.
Key words: immunologic reactivity, immune response, food allergy, cytokines, newborn, breast milk, breast milk oligosaccharides.
Key words: immunologic reactivity, immune response, food allergy, cytokines, newborn, breast milk, breast milk oligosaccharides.
LECTURE
88-92 435
Abstract
The article considers aspects of infectious diseases of respiratory tract of children in St Petersburg; determines the role of lingering and recurrent variations of the respiratory diseases; gives data on the basic factors of forming lingering and recurrent respiratory diseases. The article identifies the role of Immuno-correction in the treatment of unfavorably developing of bron chopulmonary diseases. It gives the findings of a clinical test of applying immuno-corrected medication with a high curative effect of the therapy.
93-96 871
Abstract
The article considers one of the topical issues of children's gas troenterology — disturbance of the pancreas functioning, its possible reasons and clinical manifestations, as well as diagnostics and treatment issues. The article considers the requirements for enzymatic medications to efficiently correct the excretory insufficiency of the pancreas. The authors describe a high performance medication for this case, demonstrate its features.
Key words: excretory insufficiency pancreas, treatment, enzymatic medications, children.
Key words: excretory insufficiency pancreas, treatment, enzymatic medications, children.
For Pediatricians' Practice
97-100 418
Abstract
The article highlights one of the most frequent children's microbial and inflammatory diseases — a urinary system infection. The authors discuss the issues of etiopathogenesis, clinical manifestations and diagnostics of this pathology. They also share their own experience in treatment of the excretory tract infections.
Key words: urinary tracts infection, clinical picture, diagnostics, treatment, children.
Key words: urinary tracts infection, clinical picture, diagnostics, treatment, children.
101-105 1981
Abstract
Acute respiratory infections are the most widely spread pathology in the children. They do not belong to the category of severe, incapacitating diseases, but they considerably worsen the general condition of the child and are dangerous through their life threatening complications. It is very important to start the etiotropic antiviral therapy and whenever possible, quickly to stop disease manifestations, without any harm for child. The proposed article is devoted to the optimization of the symptomatic therapy in the event of the given pathology.
Key words: acute respiratory infections, symptoms, treatment, children.
Key words: acute respiratory infections, symptoms, treatment, children.
106-109 500
Abstract
The calcium deficiency problem becomes especially topical considering its worldwide proliferation in the overall population and the especial significance of the calcium metabolism disturbance among kids and teenagers. Analysis of metabolism of that macromineral reveals the reasons why a body lacks calcium during the period of intensive growth, identifies ways to fix this problem with the help of adjusted alimentary and medicated input of calcium.
Key words: calcium, children, teenagers, bone tissue metabolism.
Key words: calcium, children, teenagers, bone tissue metabolism.
110-115 17694
Abstract
Disturbances of nutritive status are typical of patients with non specific ulcerative colitis и crohn's disease with such symptoms as body weight deficiency, disturbance of metabolism associated with the lack of proteins, macro and microelements, energy substrata. Nutrition plays a key role not only in the growth and development processes but also is one of the crucial factors determining the adequacy of the inflammatory response, adaptation compensatory processes. The article considers issues of medicated nutrition under this pathology, including the basic diet, usage of specialized mixes and enteral feeding to correct the protein energy disturbances, and as an independent treatment method.
Key words: crohn's disease, non-specific ulcerative colitis, children, diet, enteral feeding, bowel disease.
Key words: crohn's disease, non-specific ulcerative colitis, children, diet, enteral feeding, bowel disease.
116-120 428
Abstract
The article considers issues of therapeutic tactics for virus infections of children. The authors explain the essence of changes, which take place in the immune system of body under this pathology. The article describes immuno pathogenesis of acute enteric infections and the effect of lactoprobiotics on immuno-competent cells. The findings prove the advisability of applying this group of medications for a complex therapy of children with acute diarrhea disturbance.
Key words: acute enteric infections, immuno-pathogenesis, treatment, lacto probiotics, children.
Key words: acute enteric infections, immuno-pathogenesis, treatment, lacto probiotics, children.
121-123 485
Abstract
The researchers introduce the results of analysis of outcomes of operation in 38 children (7–15 years old) with liver cirrhosis and portal hypertension. The duration of the disease was from 2 to 12 years. recurrent 2–5 hemorrhages were hoted in 17 (44,7%) of the patients. the analysis of surgical interventions have shown that Tanner–Bairov`s operation was preferable among non bupassing and non traumatic operations.
Key words: liver cirrhosis, portal hypertension, hemorrhage, conservative therapy, surgical correction, children.
Key words: liver cirrhosis, portal hypertension, hemorrhage, conservative therapy, surgical correction, children.
FROM THE UNION OF PEDIATRICIANS OF RUSSIA
SHORT REPORT
137-139 470
Abstract
The article highlights the information on the technology of the vitamin and mineral complexes production, actions to ensure not only high quality production but also safety for the staff and environmental protection.
Key words: vitamin and mineral complexes, production technologies.
Key words: vitamin and mineral complexes, production technologies.
140 399
Abstract
From the Editor:
Dear Colleagues! It is becoming a tradition to acquaint you with the most relevant issues discussed at scientific conferences and congresses held both in our country and abroad. This time we want to discuss a conference "Movement against allergy" organized by the European Academy which was held in Prague on 7-8 March 2008 and was dedicated to food allergies in children.
Dear Colleagues! It is becoming a tradition to acquaint you with the most relevant issues discussed at scientific conferences and congresses held both in our country and abroad. This time we want to discuss a conference "Movement against allergy" organized by the European Academy which was held in Prague on 7-8 March 2008 and was dedicated to food allergies in children.
TRAINING FOR TRAINERS — EDUCATIONAL PROGRAM FOR PARENTS
142-146 561
Abstract
The article presents classification and pathogenic mechanism of fever among children; the clinical course of the disease. The authors remind pediatricians about the necessity to differentiate approaches of managing patients with fever depending on its type («pink» or «pale»). Moreover, the article considers indications for treatment with antipyretic medicine and principles for choosing this or that type of medicine to keep the fever down pharmacologically.
Key words: fever, classification, treatment, children.
Key words: fever, classification, treatment, children.
147-148 432
Abstract
Authors acquaint colleagues with the basic aspects of one of the most threatening disease of xxi century — cervical cancer, whose viral etiology is now beyond any doubt. They also showed an efficient method of prevention, which is vaccination against HPV, whose oncogenic strains are the main etiological factor of this disease.
Key words: papillomavirus infection, cervical cancer, prevention, vaccination.
Key words: papillomavirus infection, cervical cancer, prevention, vaccination.
ISSN 1727-5776 (Print)
ISSN 2500-3089 (Online)
ISSN 2500-3089 (Online)
