HEMODYNAMIC EFFECTS OF XENON ANESTHESIA IN CHILDREN
https://doi.org/10.15690/pf.v11i3.1007
Abstract
The study was aimed at hemodynamic effects of xenon on operative interventions in children. Patients and methods: the study involved 30 5-17-year-old children – 10 (33.3%) girls and 20 (66.7%) boys with ASA score 1-3 admitted for surgical treatment. The children underwent endotracheal anesthesia with xenon-oxygen mixture (Xe:O2 = 60-65:30%) and fentanyl (2.5‑3.5 mcg/kg per hour) for the following operations: appendectomy – 10 (33.3%) patients, herniotomy – 8 (26.7%) patients, Ivanissevich procedure – 6 (20.0%) patients, plastic surgery of posttraumatic defects of skin and soft tissues – 4 (13.3%) patients, abdominal adhesiotomy – 2 (6.7%) patients. Central hemodynamics was studied echocardiographically (Philips HD 11, the Netherlands) using the Teichholz technique along the cephalocaudal axis (parasternal access). Results: the anesthesia was notable for hemodynamic stability during the operation: as a result, a statistically significant (p < 0.05) increase in systolic, diastolic and mean arterial pressure by 10, 18 and 17%, respectively, was observed. Conclusion: the analysis demonstrated that xenon anesthesia improves lusitropic myocardial function statistically significantly increasing cardiac output by 12% by way of increasing stroke volume by 30%.
About the Authors
M. V. Bykov
Research institute of pediatric surgery and traumatology, Moscow
Russian Federation
Russian Federation
MD, anesthesiologist and resuscitation specialist at the department of anesthesiology and resuscitation of the research institute of emergency pediatric surgery and traumatology
V. G. Bagaev
Research Institute of Pediatric Surgery and Traumatology, Moscow, Russian Federation
Russian Federation
Russian Federation
V. G. Amcheslavskiy
Research Institute of Pediatric Surgery and Traumatology, Moscow, Russian Federation
Russian Federation
Russian Federation
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For citations:
Bykov M.V., Bagaev V.G., Amcheslavskiy V.G. HEMODYNAMIC EFFECTS OF XENON ANESTHESIA IN CHILDREN. Pediatric pharmacology. 2014;11(3):42-47. https://doi.org/10.15690/pf.v11i3.1007
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