VARIOUS TYPES OF ANAESTHESIA WITH XENON IN CHILDREN
https://doi.org/10.15690/pf.v9i1.167
Abstract
Since 2010 till 2011 years by authority of Ministry of Health and social development of Russian Federation the clinical trial IIIA on evaluation of xenon efficacy and safety in anaesthesia in children (ASA I–III) with different surgical diseases has been performed. 60 anaesthesias with xenon in children at the age of 1–18 years were made: face mask — 3 (5%), laryngeal mask — 9 (15%), endotracheal — 48 (80%). Face mask monoanaesthesia with xenon has prolonged duration, difficulties in maintenance of outline airtightness and is expensive because of gas consumption, so this method was defined as unpromising. The optimal anaesthesia with xenon is laryngeal mask or endotracheal anaesthesia. Before all types of anaesthesia premedication with 0,1% atropine sulfate must be performed. Induction and initial anaesthesia in children younger than 5 years old should be performed with sevoflurane through face mask, in children older than 5 years — with propofol. The analgesia with xenon concentration in respiratory-anaesthesia mixture is insufficient and requires the intensification by intravenous phentanylum.
About the Authors
V. G. Bagaev
НИИ неотложной детской хирургии и травматологии, Москва
Russian Federation
Russian Federation
E. V. Devaykin
Областная детская клиническая больница № 1, Екатеринбург
Russian Federation
Russian Federation
V. G. Amtcheslavskiy
НИИ неотложной детской хирургии и травматологии, Москва
Russian Federation
Russian Federation
V. N. Potapov
ООО «Акела-Н», Сходня
Russian Federation
Russian Federation
S. N. Boyarskiy
Областная детская клиническая больница № 1, Екатеринбург
Russian Federation
Russian Federation
References
1. Boomsma F., Rupreht J., Veld A.J. et al. Haemodynamic and neurohumoral effects of xenon anaesthesia. A comparison with nitrous oxide. Anaesthesia. 1990; 45: 273-8.
2. Lachmann B., Armbruster S., Schairer W. et al. Safety and efficacy of xenon in routine use as an inhalational anaesthetic. Lancet. 1990; 335: 1413-1415.
3. De Sousa S.L., Dickinson R., Lieb W.R. Contrasting synaptic actions of the inhalational general anesthetics isoflurane and xenon. Anesthesiology. 2000; 92: 1055-1066.
4. Goto T., Nakata Y., Morita S. The minimum alveolar concentration of xenon in the elderly is sex-dependent. Anesthesiology. 2002; 1129-32.
5. Sanders R.D., Weimann J., Maze M. Biologic Effects of Nitrous Oxide: A Mechanistic and Toxicologic Review. Anesthesiology. 2008; 109 (4): 707-722.
6. Shulunov M.V. Evaluation of the adequacy of xenon anesthesia according to hormonal, hemodynamic and biochemical parameters. Thesis. PhD. M. 1995; P.25.
7. Stuttmann R., Jakubetz J., Schultz K. et al. Recovery index, attentiveness and state of memory after xenon or isoflurane anaesthesia: a randomized controlled trial. BMC Anesthesiol. 2010; 10: 5.
8. Raschupkin A.B., Burov N.E. Changes of central hemodynamics during xenon anesthesia and nitrous oxide in patients with compromised cardiovascular system. Anesthesiology and Intensive Care. 2006; 4: 50.
9. Burov N.E., Molchanov I.V., Nikolaev, L.L. etc. The method low flowed xenon anesthesia. Anesthesiology and Intensive Care. 2003; 3: 31-34.
10. Dahmani S., Stany I., Brasher C. et al. Pharmacological prevention of sevoflurane-and desflurane-related emergence agitation in children: a metaanalysis of published studies. Br J Anaesthesiol. 2010; 104: 216-23.
11. Goto T., Saito H., Nakata Y. et al. Emergence times from xenon anaesthesia are independent of the duration of anaesthesia. Br J Anaesthesiol. 1997; 79: 595-9.
12. Burov N.E., Jabarov D.A., Ostapchenko D.A. and others. Clinical stages and subjective sensations in xenon anesthesia. Anesthesiology and Intensive Care. 1993; 4: 7-11.
13. Burov N.E., Mironova, I.I., Kornienko L.Y. and others. Effect of xenon anesthesia on the morphology and blood clotting. Anesteziololgiya and reanimation. 1993; 6: 14-17.
Review
For citations:
Bagaev V.G., Devaykin E.V., Amtcheslavskiy V.G., Potapov V.N., Boyarskiy S.N. VARIOUS TYPES OF ANAESTHESIA WITH XENON IN CHILDREN. Pediatric pharmacology. 2012;9(1):72-76. https://doi.org/10.15690/pf.v9i1.167
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