Peculiarities of differential diagnosis of malignant and benign ovarian tumors in girls (case report of immature teratoma of the ovary)
Elena V. Sibirskaya,
Irina V. Karachentsova,
Ivan N. Skapenkov,
Andrey A. Naumenko,
Ivan I. Petinov,
Polina O. Nikiforova https://doi.org/10.15690/pf.v20i3.2585
Abstract
Germ cell tumors are a heterogeneous group of tumors differentiating from primary germ cells of embryonic gonads and their derivatives. This case report demonstrates the diagnostic algorithm and diagnostic tactics of a rarely encountered histological type of ovarian germ cell tumor.
Keywords
clinical case,
malignant ovarian tumors,
ovarian germ cell tumors,
immature ovarian teratoma,
alpha-fetoprotein,
computed tomography,
midline laparotomy,
adnexectomy
Supporting agencies: Not specified
About the Authors
Elena V. Sibirskaya
A.I. Yevdokimov Moscow State University of Medicine and Dentistry; Russian Children’s Clinical Hospital of Pirogov Russian National Research Medical University; Pirogov Russian National Research Medical University; Dolgoprudnenskaya Central City Hospital
Russian Federation
Disclosure of interest:
Russian Federation
MD, PhD, Professor.
117, Leninskiy avenue, Moscow, 119571
Tel.: +7 (916) 359-15-37
Disclosure of interest:
Not declared
Irina V. Karachentsova
Pirogov Russian National Research Medical University
Russian Federation
Disclosure of interest:
Russian Federation
MD, PhD.
Moscow
Disclosure of interest:
Not declared
Ivan N. Skapenkov
Russian Children’s Clinical Hospital of Pirogov Russian National Research Medical University
Russian Federation
Disclosure of interest:
Russian Federation
MD.
Moscow
Disclosure of interest:
Not declared
Andrey A. Naumenko
Pirogov Russian National Research Medical University
Russian Federation
Disclosure of interest:
Russian Federation
MD.
Moscow
Disclosure of interest:
Not declared
Ivan I. Petinov
Pirogov Russian National Research Medical University
Russian Federation
Disclosure of interest:
Russian Federation
MD.
Moscow
Disclosure of interest:
Not declared
Polina O. Nikiforova
Pirogov National Medical and Surgical Center
Russian Federation
Disclosure of interest:
Russian Federation
MD.
Moscow
Disclosure of interest:
Not declared
References
1. Savel'eva GM, Sukhikh GT, Serov VN. Akusherstvo: State manual. Moscow: GEOTARMedia; 2020. (In Russ).
2. Callahan TL, Caughey AB. Blueprints Obstetrics & Gynecology. 7th ed. Wolters Kluwer; 2018. 1312 p.
3. Saleh M, Bhosale P, Menias CO, et al. Ovarian teratomas: clinical features, imaging findings and management. Abdom Radiol (NY). 2021;46(6):2293-2307. doi: https://doi.org/10.1007/s00261-020-02873-0
4. Sibirskaya EV, Sharkov SM, Shostenko AV, Medvedeva AO. Malignant neoplasms of ovaries in children and adolescents. Detskaya khirurgiya = Russian Journal of Pediatric Surgery. 2018;22(5):258-262. (In Russ). doi: https://doi.org/10.18821/1560-9510-2018-22-5-258-262
5. Lyadov VK, Pushkaryov VA, Cherepanova EV, et al. Difficulties in diagnosis and treatment of immature ovarian teratoma: a clinical case study. Onkoginekologiya. 2020;(3):29-35. (In Russ).
6. Ray-Coquard I, Trama A, Seckl MJ, et al. Rare ovarian tumours: Epidemiology, treatment challenges in and outside a network setting. Eur J Surg Oncol. 2019;45(1):67-74. doi: https://doi.org/10.1016/j.ejso.2017.09.025
7. Vyal'tseva MA. Nezrelaya teratoma yaichni-ka. I All-Russian scientific and practical conference “Sovremennaya patologiya: opyt, problemy, perspektivy”: Abstract book. Samara; 2020. pp. 239-243. (In Russ).
8. Kajal P, Bhutani N, Saini K, Kadian P. Immature ovarian teratoma in childhood: Case report of successful management of a monster mass in a preschool girl. Ann Med Surg (Lond). 2022;80:104147. doi: https://doi.org/10.1016/j.amsu.2022.104147
9. Vyal'tseva MA, Yunusova YuR, Kirichenko ND. Kliniko-morfologicheskii analiz teratom yaichnika. Fundamental'naya nauka v sovremennoi meditsine — 2021. Minsk: Belarusian State Medical University; 2021. pp. 375-378. (In Russ).
10. Zhordania KI, Kalinicheva EV, Moiseev AA. Ovarian cancer: epidemiology, morphology and histogenesis. Onkoginekologiya. 2017;(3):26-32. (In Russ).
11. Dmitriev VN, Dobrokhotova YuE, Mukhina TS, et al. Malignant ovarian germ cell tumors. Literature review. Onkoginekologiya. 2017;(3):23-32. (In Russ).
12. Adamyan LV, Sibirskaya EV, Bogdanova EA, et al. Ovarian benign tumors and tumor-like formations of girls and young women (a review). Problemy Reproduktsii = Russian Journal of Human Reproduction. 2016;22(2):73-77. doi: https://doi.org/10.17116/repro201622273-77 (In Russ).
13. Hastings CA, Torkildson JC, Agrawal AK. Handbook of Pediatric Hematology and Oncology: Children's Hospital and Research Center Oakland. 3rd ed. John Wiley & Sons; 2021. 512 p.
14. Mahendra INB, Saspriyana KY, Ekawati NP. Mature ovarian teratoma associated with anti-N-Methyl-D-aspartate receptor encephalitis: A case report. Med J Malaysia. 2021;76(1):110-113.
15. Imataka G, Yoshihara S. Immature ovarian teratoma with anti-NMDA-receptor encephalitis in a 13-year-old Japanese female patient. Med J Malaysia. 2021;76(3):436-437.
16. Wu CY, Wu JD, Chen CC. The association of ovarian teratoma and Anti-N-Methyl-D-Aspartate receptor encephalitis: an updated integrative review. Int J Mol Sci. 2021;22(20):10911. doi: https://doi.org/10.3390/ijms222010911
17. Jamshidi P, Taxy JB. Educational Case: Yolk Sac (Endodermal Sinus) Tumor of the Ovary. Acad Pathol. 2020;7:2374289520909497. doi: https://doi.org/10.1177/2374289520909497
18. Xie S, Jia X, Li T, et al. Pelvic masses after surgery for immature ovarian teratoma: A 10-year experience of Western China. Medicine (Baltimore). 2022;101(31):e29727. doi: https://doi.org/10.1097/MD.0000000000029727
19. Rousseau MC, Demarche M, Dresse MF, David BA. Teratome ovarien chez l'enfant. Rev Med Liege. 2022;77(1):39-44.
20. Textbook of Obstetrics and Gynaecology: a life course approach. Steegers EAP, Fauser BCJM, Hilders CGJM, eds. Bohn Stafleu van Loghum; 2019. doi: https://doi.org/10.1007/978-90-368-2131-5
21. Nechushkina IV, Nechushkina VM, Boichenko EI, et al. Opyt lecheniya detei s germinogennymi opukholyami yaichnikov: istoricheskii obzor. Russian Medical Inquiry. 2019;3(3):20-21. (In Russ).
22. Fonseca A, Frazier AL, Shaikh F. Germ cell tumors in adolescents and young adults. J Oncol Pract. 2019;15(8):433-441. doi: https://doi.org/10.1200/JOP.19.00190
Review
For citations:
Sibirskaya E.V., Karachentsova I.V., Skapenkov I.N., Naumenko A.A., Petinov I.I., Nikiforova P.O. Peculiarities of differential diagnosis of malignant and benign ovarian tumors in girls (case report of immature teratoma of the ovary). Pediatric pharmacology. 2023;20(3):256-260. (In Russ.) https://doi.org/10.15690/pf.v20i3.2585
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