HOW TO DISTINGUISH A BACTERIAL INFECTION FROM A VIRAL ONE AND HOW TO TREAT IT
https://doi.org/10.15690/pf.v10i4.768
Abstract
The article is dedicated to the most relevant issue of childhood – febricities, the causes of which and, subsequently, correct patient management tactics are difficult to determine. The authors present not only their own experience of clinical and laboratory differential diagnostics of viral and bacterial infections, but also the world literature data. Low bacterial infection risk criteria, which allow avoiding the prescription of antibacterial drugs, are listed. Special attention is given to the most important inflammation markers at various febrile diseases and signs of a severe bacterial infection and fever without an apparent infection’s nidus. The authors recommend using express tests to confirm the presence of a bacterial infection. Indications to antibacterial therapy prescription are analyzed.
About the Authors
M. D. Bakradze
Scientific Center of Children’s Health, Moscow
Russian Federation
PhD, head of the diagnostics and medical rehabilitation department at the SCCH of RAMS
Russian Federation
PhD, head of the diagnostics and medical rehabilitation department at the SCCH of RAMS
I. V. Chashchina
Scientific Center of Children’s Health, Moscow, Russian Federation
Russian Federation
Russian Federation
V. K. Tatochenko
Scientific Center of Children’s Health, Moscow, Russian Federation
Russian Federation
Russian Federation
I. L. Mityushin
Scientific Center of Children’s Health, Moscow, Russian Federation
Russian Federation
Russian Federation
References
1. Trautner B. W., Caviness A. C., Gerlacher G. R., Demmler G., Macias C. G. Prospective evaluation of the risk of serious bacterial infection in children who present to the emergency department with hyperpyrexia (temperature of 106 degrees F or higher. Pediatrics. 2006; 118 (1): 34–40.
2. Gomez B. et al. Diagnostic value of procalcitonin in wellappearing young febrile infants. Pediatrics. 2012 Nov; 130: 815.
3. Starovoitova E. V. et al. Pediatricheskaya farmakologiya = Pediatric pharmacology. 2007; 4 (3): 45–49.
4. Tatochenko V. K. Bolezni organov dykhaniya u detei [Respiratory Diseases in Children]. Moscow, «Pediatr""», 2012. 480 p.
5. Huppler A. R. Performance of low-risk criteria in the evaluation of young infants with fever: review of the literature. Pediatrics. 2010; 125 (2): 228–33.
6. Tahtinen P. A. et al. A placebo-controlled trial of antimicrobial treatment for acute otitis media. N. Engl. J. Med. 2011; 364: 116.
7. Baranov A. A., Tatochenko V. K., Bakradze M. D. Likhoradochnye sindromy u detei: rekomendatsii po diagnostike i lecheniyu [Febrile Syndromes in Children: Recommendations for Diagnosis and Treatment]. Moscow, Soyuz pediatrov Rossii, 2011. 228 p.
8. Armengol C. E., Hendley J. O. Occurrence of Group A _-Hemolytic Streptococcal Pharyngitis in the Four Months After Treatment of an Index Episode With Amoxicillin Once-daily or Twice-daily or With Cephalexin. Pediatr. Infect. Dis. J. 2012; 31 (11): 1124–1127.
9. Bakradze M. D., Darmanyan A. S. Voprosy diagnostiki v pediatrii = Diagnostics in pediatrics. 2009; 1 (2): 56–61.
10. Chow A. W., Benninger M. S., Brook I. et al. IDSA clinical practice guideline for acute bacterial rhinosinusitis in children and adults. Clin. Infect. Dis. 2012; 54: 1041–1045.
11. Van Rossum et al. ESPID 30th Annual Meeting. Thessaloniki. May 11, 2012.
12. Vollkov K., Namazova l.L., Nisevich L. Clamydia, mycoplasma and viral infections in children with chronic cough. Abstracts for the 3rd Europaediatrics Congress 2008. p. 400.
13. Volkov K.S., Nisevich L.L., Namazova-Baranova L.S., Filyanskaya E.G., Alekseeva A.A., Barannik V.A. Voprosy sovremennoi pediatrii = Current pediatrics. 2013; 2 (1): 112–116.
14. Okazanie statsionarnoi pomoshchi detyam. Rukovodstvo po vedeniyu naibolee rasprostranennykh zabolevanii v usloviyakh ogranichennykh resursov. Vsemirnaya organizatsiya zdravookhraneniya [Hospital Care for Children. Guidelines for the Management of Common Illnesses with Limited Resources. World Health Organization]. EUROPA, 2006. 399 p.
15. Tatochenko V. K., Bakradze M. D. Farmateka = Pharmateca. 2009; 14 (188): 36–41.
16. Craig J. C. et al. The accuracy of clinical symptoms and signs for the diagnosis of serious bacterial infection in young febrile children. BMJ. 2010; 340: 1594.
17. Colvin J. M., Muenzer J. T., Jaffe D. M. et al. Detection of viruses in young children with Fever without an apparent source. Pediatrics. 2012 Dec; 130 (6): 1455–62.
18. Bakradze M. D., Tatochenko V. K. Infektsionnye bolezni = Infectious diseases. 2008; 6 (2): 78–81.
Review
For citations:
Bakradze M.D., Chashchina I.V., Tatochenko V.K., Mityushin I.L. HOW TO DISTINGUISH A BACTERIAL INFECTION FROM A VIRAL ONE AND HOW TO TREAT IT. Pediatric pharmacology. 2013;10(4):139-144. https://doi.org/10.15690/pf.v10i4.768
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