Cardiac Tumor in Newborn as the Marker of Tuberous Sclerosis: Clinical Case
https://doi.org/10.15690/pf.v17i2.2101
Abstract
Background. The most common cardiac tumor in children is rhabdomyoma. Its frequency is 58.3% in the early neonatal period. Rhabdomyoma is associate with tuberous sclerosis pretty often (50-86% of all cases) and it be its diagnostic marker.
Clinical case description. This article presents case study of the newborn from the mother with burdened obstetric and gynecological anamnesis, type 1 diabetes, nicotine addiction. Multiple mass lesions were revealed in the child’s heart on the 31 st week of gestation. On examination: systolic murmur over the heart region, fibrous nodules on the skin all over the body up to 1-5 mm in diameter, indurated on palpation. Diagnosed echocardiographically: multiple attached, round masses were revealed in the cavity of left ventricle of 7.9×4.1 mm in size, in outflow track of left ventricle (near the aortic root) — 9.3×4.8 mm, in the cavity of right ventricle — 4.3×3.2 mm, in the cavity of right auricle — 5.1×5.0 mm. Pathologic activity of cardiac conduction system was presented only by single supra-ventricular and ventricular extrasystoles due to the results of 24-hour monitoring.
Conclusion. Children with cardiac rhabdomyoma diagnosed in prenatal period are threatened by tuberous sclerosis, thus, complex dynamic observation and molecular genetic testing is needed.
Supporting agencies: Not specified.
About the Authors
Elena I. Naumenko
Mordovian Republican Clinical Perinatal Center; Medicine Institute of N.P. Ogarev Mordovia State University
Russian Federation
Saransk
Disclosure of interest:
Russian Federation
Saransk
Disclosure of interest:
The authors of the article confirmed the absence of a conflict of interest, which must be reported.
Valeria G. Anufrieva
Mordovian Republican Clinical Perinatal Center
Russian Federation
Saransk
Disclosure of interest:
Russian Federation
Saransk
Disclosure of interest:
The authors of the article confirmed the absence of a conflict of interest, which must be reported.
Irina A. Grishutkina
Medicine Institute of N.P. Ogarev Mordovia State University
Russian Federation
Saransk
Disclosure of interest:
Russian Federation
Saransk
Disclosure of interest:
The authors of the article confirmed the absence of a conflict of interest, which must be reported.
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Review
For citations:
Naumenko E.I., Anufrieva V.G., Grishutkina I.A. Cardiac Tumor in Newborn as the Marker of Tuberous Sclerosis: Clinical Case. Pediatric pharmacology. 2020;17(2):148-151. (In Russ.) https://doi.org/10.15690/pf.v17i2.2101
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