Vol 3, No 1 (2006)
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AN EDITORIAL ARTICLE
ORIGINAL ARTICLES
13-17 470
Abstract
The article is devoted to prevention and treatment of acute respiratory diseases children of megapolises who fall ill frequently. The authors prove the thesis that children falling ill frequently and residing in mega cities, and not only in Russia, have a similar immune status, according to which not only therapeutic but also preventive immunomodulatory treatment courses must be administered to them.
Key words: frequently ill children, bacterial immunomodulation, cytokinic status.
Key words: frequently ill children, bacterial immunomodulation, cytokinic status.
66-70 500
Abstract
The article advances arguments for an active introduction of the logbook system in medical institutions. The main algorithm of the logbook committee establishment, its role in the work of a medical institution, its main functions and powers are briefly set forth. The article presents algorithms for the creation of a logbook list of medicinal remedies and carrying on ABC and ven analyses by the log book therapeutic committee. The main criteria for the inclusion of a medicine in the logbook are pre-sented.
Key words: ensuring of medicinal remedies provision, logbook committee, log book system.
Key words: ensuring of medicinal remedies provision, logbook committee, log book system.
18-21 467
Abstract
The study demonstrates that uncontrolled bronchial asthma with persistent nocturnal symptoms may lead to sleep structure disturbance, making it less effective. An adequate anti-inflammatory therapy using state-of-the-art medicinal means helps to control the disease, arrest nocturnal symptoms, resulting in sleep structure restoration and the improvement of its quality thus improving life quality of patients as well as their parents.
Key words: bronchial asthma, sleep disturbance, polysomnography, flutikazon, salmeterol.
Key words: bronchial asthma, sleep disturbance, polysomnography, flutikazon, salmeterol.
PHARMACOECONOMICS IN PEDIATRICS
22-27 393
Abstract
Invasive candidiasis in premature neonates is characterized by frequent and attributive mortality. The authors carried out clinical and economic analysis of invasive candidiasis prevention in neonates with very low body mass at the delivery by means of flukonazol in the doses of 3 and 6 mg/kg. 104 neonates receiving prophylactic treatment with flukonazol comprised the main group, 249 prophylaxis free neonates comprised the control group. The study was prospective, analytical, randomized, cotrolled and clinical. such pharmacoeconomical analyses as disease cost, minimization and effectiveness of expenses were used. the study demonstrated that the greatest direct expenses in the process of candidiasis treatment were for hospital stay (81%) and the least ones for flukonazol (4%). pharmacoeconomical analysis of the obtained data showed that prophylactic dose of 3 mg/kg of flukonazol is more effective than that of 6 mg/kg or keeping premature prophylaxis free neonates in the ICU.
Key words: invasive candidiasis, very low body mass at the delivery, pharmacoeconomical analysis, premature neonates.
Key words: invasive candidiasis, very low body mass at the delivery, pharmacoeconomical analysis, premature neonates.
CLINICAL RECOMMENDATIONS
LECTURE
41-44 1210
Abstract
Vaccination is the easiest and economically effective means of control of infectious diseases in all social population groups of industrial and developing countries. The implementation of the who conception of comprehensive immunization program adopted in 1974 has brought about a significant decrease of the main pediatric infections incidence. While formerly mass immunization was aimed at the decrease of pediatric morbidity and mortality caused by infections, nowadays immunoprophylaxis is mainly aimed at the maintenance of the achieved beneficial epidemiological situation. It necessitates the continuation of mass vaccination of not less than 95% of children during their first years of life as well as the establishment of partner relations with parents and mass media.
Key words: immunoprophylaxis, pediatric infectious diseases.
Key words: immunoprophylaxis, pediatric infectious diseases.
DEBATABLE ISSUES OF PHARMACOTHERAPY
For Pediatricians' Practice
THE IMPACT OF THE NASAL SPRAY FLUTIKAZON ON THE LOCAL IMMUNITY INDICES IN ALLERGIC RHINITIS PATIENTS
72-74 533
Abstract
Medical library. medications – common over the counter medications the impact of a topical glucocorticoid flutikazon on the dynamics of the local immunity indices and microbiocenosis condition of the nasal mucosa was studied in the patients with the confirmed diagnosis of all the year round allergic rhinitis. In a year all patients demonstrated a sustained control of all the year round allergic rhinitis symptoms. A statistically significant increase of lysozyme, secretory and interferon γ concentration in the nasal and mouth mucous secretion as well as the decrease of tumor necrosis factor (TNF) α concentration and the frequency of yeast like fungi and gram negative bacteria growth were revealed. Thus, long term flutikazon therapy has brought about a sustained remission of all the year round allergic rhinitis clinical manifestations as well as a significant improvement of microbiocenosis indices of the upper respiratory mucous membranes and local immunity indices.
Key words: allergic rhinitis, local immunity, mucous membranes microbiocenosis, topical glucocorticoids.
Key words: allergic rhinitis, local immunity, mucous membranes microbiocenosis, topical glucocorticoids.
GUIDE FOR AUTHORS
ISSN 1727-5776 (Print)
ISSN 2500-3089 (Online)
ISSN 2500-3089 (Online)
