USE OF INTERFERON BETA-1A FOR INTRAMUSCULAR ADMINISTRATION IN CHILDREN AND ADOLESCENTS WITH MULTIPLE SCLEROSIS: EFFICACY, SAFETY AND ADHERENCE TO THERAPY
Abstract
Immunomodulatory drugs reduce relapse rate and disease progression in relapsing-remitting multiple sclerosis but extensive data are not available on the effectiveness and tolerability of these drugs in childhood or adolescence. Interferon beta tolerability biased by frequency and method of drug administration. Drug administration has great impact on treatment compliance and adherence. That’s why we discuss moreover interferon beta 1a intramuscular as perspective immunomodulative medication in pediatric MS cohort.
Key words: immunomodulatory drugs, interferon beta, multiple sclerosis, compliance, adherence, adolescence, childhood.
Key words: immunomodulatory drugs, interferon beta, multiple sclerosis, compliance, adherence, adolescence, childhood.
About the Authors
O.V. Bykova
Scientific Center of Children’s Health, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
T.V. Sidorenko
Russian State Medical University, Moscow
Russian Federation
Russian Federation
A.N. Platonova
Russian State Medical University, Moscow
Russian Federation
Russian Federation
N.V. Gol’tsova
Russian State Medical University, Moscow
Russian Federation
Russian Federation
L.M. Kuzenkova
Scientific Center of Children’s Health, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
A.N. Boiko
Russian State Medical University, Moscow
Russian Federation
Russian Federation
Review
For citations:
Bykova O., Sidorenko T., Platonova A., Gol’tsova N., Kuzenkova L., Boiko A. USE OF INTERFERON BETA-1A FOR INTRAMUSCULAR ADMINISTRATION IN CHILDREN AND ADOLESCENTS WITH MULTIPLE SCLEROSIS: EFFICACY, SAFETY AND ADHERENCE TO THERAPY. Pediatric pharmacology. 2009;6(5):14-19.
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