STUDYING IMMUNOBIOLOGICAL FEATURES OF PREPARED WATER_SALT EXTRACTS OF INSECT ALLERGENS
Abstract
Through the indirect degranulation of mast cells, anaphylaxis test, solid phase immune enzyme analysis, the researchers evaluated the immuno biological features of serum of 20 patients suffering from atopic mild and moderate bronchial asthma with domestic sensitization. All received water salt extracts of insects (cockroach, black beetle, American cock roach, ash gray cockroach, cricket, fly, moth, mealworm, weevil, billbug) demonstrated specific activity. An immune enzyme analysis has revealed more intensive allergic features of substances extracted from black beetle, cockroach, fly and moth.
Key words: insect allergens, allergen specific immunotherapy, immuno biological features of allergic extracts, Ige anti bodies.
Key words: insect allergens, allergen specific immunotherapy, immuno biological features of allergic extracts, Ige anti bodies.
About the Authors
O.V. Radikova
Mechnikov Research Institute of Vaccines and Serum, RAMS, Moscow
Russian Federation
Russian Federation
I.S. Kropotova
Mechnikov Research Institute of Vaccines and Serum, RAMS, Moscow
Russian Federation
Russian Federation
S.V. Khlgatyan
Mechnikov Research Institute of Vaccines and Serum, RAMS, Moscow
Russian Federation
Russian Federation
N.S. Petrova
Mechnikov Research Institute of Vaccines and Serum, RAMS, Moscow
Russian Federation
Russian Federation
V.M. Berzhets
Mechnikov Research Institute of Vaccines and Serum, RAMS, Moscow
Russian Federation
Russian Federation
Review
For citations:
Radikova O., Kropotova I., Khlgatyan S., Petrova N., Berzhets V. STUDYING IMMUNOBIOLOGICAL FEATURES OF PREPARED WATER_SALT EXTRACTS OF INSECT ALLERGENS. Pediatric pharmacology. 2008;5(5):48-51.
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