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INTESTINAL MICROBIOTA AND USE OF PROBIOTICS IN PEDIATRIC PRACTICE: NEWS

https://doi.org/10.15690/pf.v12i1.1245

Abstract

Condition of intestinal microbiota is a key factor of a child's health. According to the latest studies, distinctness and certain stability of every person's microbiota is to a large extent determined genetically; at the same time, microbiocenosis is sensitive to external exposure, i.e. it is labile. The article presents new data on the intestinal microflora's composition and function, as well as on the nature of interaction in the microbiocenosis-host system. Intestinal microflora directly affects formation of a child's immune system, ensures protection from pathogens and takes part in all types of metabolism. The article presents modern approaches to intestinal microflora modulation and use of probiotics to prevent and treat various pathologies in pediatric practice.

About the Authors

S. G. Makarova
Scientific Center of Children's Health, Moscow, Russian Federation Sechenov First Moscow Medical State University, Moscow, Russian Federation
Russian Federation


L. S. Namazova-Baranova
Scientific Center of Children's Health, Moscow, Russian Federation Sechenov First Moscow Medical State University, Moscow, Russian Federation Pirogov Russian National Medical Research University, Moscow, Russian Federation
Russian Federation


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Review

For citations:


Makarova S.G., Namazova-Baranova L.S. INTESTINAL MICROBIOTA AND USE OF PROBIOTICS IN PEDIATRIC PRACTICE: NEWS. Pediatric pharmacology. 2015;12(1):38-45. (In Russ.) https://doi.org/10.15690/pf.v12i1.1245

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