AGE-DEPENDENT CHARACTERISTICS OF EPIDEMIOLOGICAL PROCESS OF HEPATITIS A IN FEDERAL DISTRICTS OF RUSSIA AT CURRENT PERIOD OF TIME. BASIS OF THE NECESSITY OF SCHEDULED VACCINATION AGAINST HEPATITIS A IN CHILDREN
https://doi.org/10.15690/pf.v9i1.160
Abstract
Recently epidemiological data on maximal hepatitis A (HA) morbidity values shift to older age groups, including adolescents at the age of 15–19 years and young adults at the age 20–39 years, and decreasing significance of children as a risk group have been published. These phenomena have not been well studied and do not have satisfactory explanations. The aim of this study was to evaluate age dependent characteristics of epidemiological process of HA in Russian Federation and its federal districts during the current period of time and to determine the necessity and appropriate age of scheduled vaccination against this infection in children. The comparative analysis of age-dependent values of HA morbidity (percentage of children and adults, the rate of adults and children values, intensity) of the population in federal districts of Russian Federation in 1999, 2001 and 2010 was performed. It was established, that HA is still a significant challenge in children health in Russian Federation. The percentage of children at the age of 0–14 years among the developed the disease in 2010 (28%) does not differ significantly from that in 1999 (40%). In Far Eastern, Siberian and North-Caucasian federal districts the children morbidity constantly 4–6 times exceeds the respective values in adults. Such characteristics of HA epidemiology indicate the necessity of scheduled vaccination of children against this infection.
About the Authors
S. L. Mukomolov
FSFSN Paster Scientific Research Institute of Epidemiology and Microbiology Rospotrebnadzor, Sankt-Petersburg
I.I. Mechnikov North-West State Medical University, Sankt-Petersburg
Russian Federation
Russian Federation
I. A. Levakova
FSFSN Paster Scientific Research Institute of Epidemiology and Microbiology Rospotrebnadzor, Sankt-Petersburg
Russian Federation
Russian Federation
A. V. Stalevskaya
FSFSN Paster Scientific Research Institute of Epidemiology and Microbiology Rospotrebnadzor, Sankt-Petersburg
Russian Federation
Russian Federation
References
1. Shliakhtenko L., Plotnikova V., Levakova I. et al. Modern epidemiology of hepatitis A in the north-western region of the Russian Federation. J. Viral. Hepat. 2008; 15 (Suppl. 2): 38-42.
2. Belyakov V.D., Yafaev R.X. Epidemiology: A Textbook. Moscow: Medicine. 1989. P. 416.
3. Guidelines for Communicable Diseases / ed. Professor. Y.V.Labzin and A.P. Kazantsev. St. Petersburg: Comet. 1996. p. 245-252.
4. Viral hepatitis in the Russian Federation. An analytical review. 7th vol. / Ed. A.B. Zhebrun. St. Petersburg.: FGUN NIIEM named after Pasteur Rospotrebnadzor. 2008. p.160.
5. Klevens R.M., Miller J.T., Iqbal K. et al. The evolving epidemiology of Hepatitis A in the United States. Arch. Intern. Med. 2010; 170: 1811-1818.
6. Moon H.W., Cho J.H., Hur M. et al. Laboratory characteristics of recent hepatitis A in Korea: ongoing epidemiological shift. World J. Gastroenterol. 2010; 16: 1115-1118.
7. Dontsenko I., Kerbo N., Pullmann J. et al. Preliminary report on an ongoing outbreak of hepatitis A in Estonia. Eurosurveillance. 2011; 16 (42): 1-4.
8. Viral Hepatitis. Hepatitis A. Viral Hepatitis Prevention Board. 2009; 18 (1): 2-9.
9. Mukomolov S.L., Stalevskaya A.V., Zheleznova N.V. and others Seroepidemiology of viral hepatitis A in St. Petersburg in 2009, Magazine of Microbiology, Epidemiology and Immunobiology. 2010;5: 15-20.
10. Mukomolov S.L., Stalevskaya A.V., Zheleznova N.V. and The others. Features of epidemic process of hepatitis A, defining strategies for prevention and control of infection at this stage. Issues of modern pediatrics. 2011, 10 (3): 131-136.
11. Mukomolov S.L., L.I. Shlyakhtenko, Vale M., et al Characterization of symptomatic and latent components of the epidemic process of hepatitis A in Russian cities. Magazine of Microbiology, Epidemiology and Immunobiology. 2001; 3: 35-39.
12. Davidkin I., Zheleznova N.V., Jokinen S. et al. Molecular epidemiology of Hepatitis A in St. Petersburg, Russia, 1997-2003. J. Med. Virol. 2007, 79: 657-662.
13. Popova O.E., Kyureghyan K.K., llichenko L.U. and others Epidemiological and molecular biological analysis of increasing incidence of hepatitis A in the Republic of Tuva in the 2008 Journal of Microbiology, Epidemiology and Immunobiology. 2010; 3: 23-26.
14. Desbois D., Couturier E., Mackiewicz V. et al. Epidemiology and genetic characterization of Hepatitis A virus genotype IIA. J. Clin. Microbiol. 2010, 48: 3306-3315.
15. Frank C., Walter J., Muehlen M. et al. Major outbreak of Hepatitis A associated with orange juice among tourists, Egypt, 2004. Emerg. Infect. Dis. 2007, 13 (1): 156-158.
16. Mukomolov S.L., Parkov O.V., Sologub T.V. and other Molecular epidemiological characteristics of outbreaks of hepatitis A among workers of a network of grocery stores. Magazine of Microbiology, Epidemiology and Immunobiology. 2008; 4: 42-45.
17. Sanitary and Epidemiological Regulations SP 3.12825-10 'Prevention of hepatitis A "(approved by Resolution of Chief State Sanitary Doctor of the Russian Federation № 190 of 30.12.2010).
Review
For citations:
Mukomolov S.L., Levakova I.A., Stalevskaya A.V. AGE-DEPENDENT CHARACTERISTICS OF EPIDEMIOLOGICAL PROCESS OF HEPATITIS A IN FEDERAL DISTRICTS OF RUSSIA AT CURRENT PERIOD OF TIME. BASIS OF THE NECESSITY OF SCHEDULED VACCINATION AGAINST HEPATITIS A IN CHILDREN. Pediatric pharmacology. 2012;9(1):20-24. https://doi.org/10.15690/pf.v9i1.160
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