Preview

Pediatric pharmacology

Advanced search

ATYPICAL CELIAC DISEASE: A CLINICAL CASE

https://doi.org/10.15690/pf.v9i4.397

Abstract

Celiac disease has traditionally been associated with severe malabsorption syndrome. Recent years it was shown that among children of preschool and school-age mild cases with atypical clinical picture were dominated that leads to diagnostic difficulties. Here we are citing an example of an atypical clinical/latent celiac disease course in a child aged 4.5 years.

About the Authors

E. A. Roslavtseva
Scientific Center of Children’s Health, RAMS, Moscow
Russian Federation


N. L. Pakhomovskaya
Scientific Center of Children’s Health, RAMS, Moscow
Russian Federation


T. E. Borovik
Scientific Center of Children’s Health, RAMS, Moscow
Russian Federation


A. S. Potapov
Scientific Center of Children’s Health, RAMS, Moscow
Russian Federation


S. G. Khomeriki
Central Research Institute of Gastroenterology, Department of Health, Moscow
Russian Federation


References

1. Husby S., Koletsko S., Korponay-Szabo I. R. et al. ESPGHAN Guidelines for diagnosis of coeliac disease. J Pediatr Gastroenterol Nutr. 2012; 54 (1): 136–160.

2. Micetic-Turk D. Epidemiology of coeliac disease. In: J. Dolinsek, T. Ornik, ed. Proceedings of international coeliac disease meeting, September 2007. Maribor University Medical Center. 2007. Р. 37–48.

3. Fasano A., Catassi C. Coeliac disease in children. Best Practice Research Clinical Gastroenterology. 2005; 19 (3): 467–478.

4. Evans K. E., Sanders D. S. What is the use of biopsy and antibodies on celiac disease diagnosis? Journal of Internal Medicine. 2011; 269 (6): 572–581.

5. Maki M., Kallonen K., Lahdeaho M. L. et al. Changing pattern of childhood celiac disease in Finland. Acta Paediatr Scand. 1998; 77: 408–412.

6. Ravikumara M., Tuthill D. P., Jenkins H. R. The changing clinical presentation of coeliac disease. Arch Dis Child. 2006; 91: 969–971.

7. Telega G., Bennet T. R., Werlin S. Emerging new clinical patterns in the presentation of celiac disease. Arch Pediatr Adolesc Med. 2008; 162 (2): 164–168.

8. Garampazzi A., Rapa A., Mura S. et al. Clinical pattern of celiac disease is still changing. J Pediatr Gastroenterol Nutr. 2007; 45: 611–614.

9. Fasano A. Clinical presentation of celiac disease in the pediatric population. Gastroenterology. 2005; 128: 68–73.

10. Metha G. The changing face of celiac disease. British Journal of Hospital Medicine. 2008; 69 (2).

11. Hadjivassiliou M. et al. Gluten sensitivity: from gut to brain. Lancet Neurol. 2010; 9: 318–330.

12. Reilly N. R., Aguilar K., Hassid B. G. et al. Celiac disease in normal-weight and overweight children: clinical features and growth outcomes following a glutenfree diet. J Pediatr Gastroenterol Nutr. 2011; 53 (5): 528–531.

13. Richter T., Bossuyt X., Vermeersch P. et al. Determination of IgG and IgA antibodies against native gliadin is not helpful for the diagnosis of coeliac disease in children up to 2 years old. J Pediatr Gastroenterol Nutr. 2012; 55 (1): 21–25.

14. Fabiani E., Taccari L. M., Ratsch I. M. et al. Compliance with the gluten-free diet in adolescents with screening-detected celiac disease: a 5-year follow-up study. J Pediatr. 2000; 136 (6): 841–843.

15. McGowan K. E., Castiglione D. A., Butzner J. D. Long-term followup of celiac disease: a comparison of children who were symptomatic or ‘asymptomatic’ at diagnosis. 13th International Coeliac Symposium, April 6–8. Amsterdam. 2009. P. 46. [Abstracts].

16. Fasano A. Systemic autoimmune disorders in celiac disease. Curr Opin Gastroenterol. 2006; 22 (6): 674–679.


Review

For citations:


Roslavtseva E.A., Pakhomovskaya N.L., Borovik T.E., Potapov A.S., Khomeriki S.G. ATYPICAL CELIAC DISEASE: A CLINICAL CASE. Pediatric pharmacology. 2012;9(4):81-85. (In Russ.) https://doi.org/10.15690/pf.v9i4.397

Views: 979


ISSN 1727-5776 (Print)
ISSN 2500-3089 (Online)