Preview

Pediatric pharmacology

Advanced search

Current Clinical Guidelines for the Management of Children Over One Year of Age with Malnutrition (Protein-Energy Malnutrition)

https://doi.org/10.15690/pf.v23i4.3088

Abstract

In May 2026, the Ministry of Health of the Russian Federation approved new clinical guidelines for the management of children over one year of age with protein-energy malnutrition. The document establishes unified rules for diagnosis, assessment of severity based on weight loss and body mass index, as well as standards for nutritional management and medical care. The guidelines provide a legitimate legal basis for prescribing specialized enteral and parenteral nutrition within the framework of compulsory health insurance, which significantly expands access to nutritional support. The document was developed by members of the Union of Pediatricians of Russia, the Association of Professional Participants in Hospice Care, the Russian Gastroenterological Association, the Autonomous Non-Profit Organization “Society of Pediatric Gastroenterologists, Hepatologists and Nutritionists”, the National Association of Pediatric Rehabilitologists, the Interregional Public Organization “Scientific Community for Promoting the Clinical Study of the Human Microbiome”, and the Russian Organization of Dietitians, Nutritionists and Food Industry Specialists.

About the Authors

Anna A. Alekseeva
Pediatrics and Child Health Research Institute in Petrovsky National Research Centre of Surgery
Russian Federation

Moscow


Disclosure of interest:

Not declared



Aleksander A. Baranov
Pediatrics and Child Health Research Institute in Petrovsky National Research Centre of Surgery; Sechenov First Moscow State Medical University
Russian Federation

Moscow


Disclosure of interest:

Not declared



Tatyana T. Batysheva
Scientific and Practical Center for Pediatric Psychoneurology; Patrice Lumumba Peoples’ Friendship University of Russia
Russian Federation

Moscow


Disclosure of interest:

Not declared



Irina A. Belyaeva
Pediatrics and Child Health Research Institute in Petrovsky National Research Centre of Surgery; Pirogov Russian National Research Medical University
Russian Federation

Moscow


Disclosure of interest:

Not declared



Tatyana E. Borovik
Sechenov First Moscow State Medical University; National Medical Research Center for Children’s Health
Russian Federation

Moscow


Disclosure of interest:

Not declared



Bushueva V. Tatyana
National Medical Research Center for Children’s Health; N.P. Bochkov Research Centre for Medical Genetics
Russian Federation

Moscow


Disclosure of interest:

Not declared



Olga V. Bykova
Scientific and Practical Center for Pediatric Psychoneurology; Patrice Lumumba Peoples’ Friendship University of Russia
Russian Federation

Moscow


Disclosure of interest:

Not declared



Olga B. Gordeeva
Pediatrics and Child Health Research Institute in Petrovsky National Research Centre of Surgery; Pirogov Russian National Research Medical University
Russian Federation

Moscow


Disclosure of interest:

Not declared



Valentina I. Guzeva
Saint-Petersburg State Pediatric Medical University
Russian Federation

Saint-Petersburg


Disclosure of interest:

Not declared



Sergey A. Gureev
Russian Medical Academy of Continuous Professional Education; A.I. Burnazyan Federal Medical Biophysical Center
Russian Federation

Moscow


Disclosure of interest:

Not declared



Margarita M. Gurova
Saint-Petersburg State Pediatric Medical University
Russian Federation

Saint-Petersburg


Disclosure of interest:

Not declared



Aleksey A. Gusev
National Medical Research Center for Children’s Health
Russian Federation

Moscow


Disclosure of interest:

Not declared



Irina M. Guseva
National Medical Research Center for Children’s Health
Russian Federation

Moscow


Disclosure of interest:

Not declared



Anna N. Zavyalova
Saint-Petersburg State Pediatric Medical University
Russian Federation

Saint-Petersburg


Disclosure of interest:

Not declared



Natalya G. Zvonkova
Sechenov First Moscow State Medical University; National Medical Research Center for Children’s Health
Russian Federation

Moscow


Disclosure of interest:

Not declared



Marika I. Ivardava
Pediatrics and Child Health Research Institute in Petrovsky National Research Centre of Surgery
Russian Federation

Moscow


Disclosure of interest:

Not declared



Vladimir T. Ivashkin
Sechenov First Moscow State Medical University
Russian Federation

Moscow


Disclosure of interest:

Not declared



Elena V. Kaytukova
Pediatrics and Child Health Research Institute in Petrovsky National Research Centre of Surgery; Pirogov Russian National Research Medical University
Russian Federation

Moscow


Disclosure of interest:

Not declared



Yuriy A. Klimov
Scientific and Practical Center for Pediatric Psychoneurology; Russian State Social University
Russian Federation

Moscow


Disclosure of interest:

Not declared



Elena V. Komarova
Pediatrics and Child Health Research Institute in Petrovsky National Research Centre of Surgery; Pirogov Russian National Research Medical University
Russian Federation

Moscow


Disclosure of interest:

Not declared



Olga L. Lukoyanova
National Medical Research Center for Children’s Health
Russian Federation

Moscow


Disclosure of interest:

Not declared



Svetlana G. Makarova
National Medical Research Center for Children’s Health
Russian Federation

Moscow


Disclosure of interest:

Not declared



Andrew V. Naletov
M. Gorky Donetsk State Medical University
Russian Federation

Donetsk


Disclosure of interest:

Not declared



Leyla S. Namazova-Baranova
Pediatrics and Child Health Research Institute in Petrovsky National Research Centre of Surgery; Pirogov Russian National Research Medical University; Shenzhen MSU-BIT University
Russian Federation

Moscow, Shenzhen


Disclosure of interest:

Not declared



Dmitriy B. Nikityuk
Federal Research Centre of Nutrition, Biotechnology and Food Safety
Russian Federation

Moscow


Disclosure of interest:

Not declared



Valeriya P. Novikova
Saint-Petersburg State Pediatric Medical University
Russian Federation

Saint-Petersburg


Disclosure of interest:

Not declared



Elena V. Pavlovskaya
Russian Medical Academy of Continuous Professional Education; Federal Research Centre of Nutrition, Biotechnology and Food Safety
Russian Federation

Moscow


Disclosure of interest:

Not declared



Mariya M. Platonova
Pediatrics and Child Health Research Institute in Petrovsky National Research Centre of Surgery
Russian Federation

Moscow


Disclosure of interest:

Not declared



Elena V. Polevichenko
Pirogov Russian National Research Medical University
Russian Federation

Moscow


Disclosure of interest:

Not declared



Elena A. Poluektova
Sechenov First Moscow State Medical University
Russian Federation

Moscow


Disclosure of interest:

Not declared



Ekaterina A. Pyr’eva
Federal Research Centre of Nutrition, Biotechnology and Food Safety
Russian Federation

Moscow


Disclosure of interest:

Not declared



Adilya I. Safronova
Federal Research Centre of Nutrition, Biotechnology and Food Safety
Russian Federation

Moscow


Disclosure of interest:

Not declared



Lilia R. Selimzyanova
Pediatrics and Child Health Research Institute in Petrovsky National Research Centre of Surgery; Pirogov Russian National Research Medical University; Sechenov First Moscow State Medical University
Russian Federation

Moscow


Disclosure of interest:

Not declared



Vera A. Skvortsova
National Medical Research Center for Children’s Health; M.F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation

Moscow


Disclosure of interest:

Not declared



Ina Sokolov
National Medical Research Center for Children’s Health
Russian Federation

Moscow


Disclosure of interest:

Not declared



Tatyana N. Sorvacheva
Russian Medical Academy of Continuous Professional Education
Russian Federation

Moscow


Disclosure of interest:

Not declared



Antonina V. Starodubova
Pediatrics and Child Health Research Institute in Petrovsky National Research Centre of Surgery; Federal Research Centre of Nutrition, Biotechnology and Food Safety
Russian Federation

Moscow


Disclosure of interest:

Not declared



Tatyana V. Strokova
Pediatrics and Child Health Research Institute in Petrovsky National Research Centre of Surgery; Federal Research Centre of Nutrition, Biotechnology and Food Safety
Russian Federation

Moscow


Disclosure of interest:

Not declared



Andrey N. Surkov
Pediatrics and Child Health Research Institute in Petrovsky National Research Centre of Surgery; Pirogov Russian National Research Medical University
Russian Federation

Moscow


Disclosure of interest:

Not declared



Valentin V. Syt’kov
Russian University of Medicine; Federal Research and Clinical Center of Children and Adolescents
Russian Federation

Moscow


Disclosure of interest:

Not declared



Nataliya N. Taran
Pediatrics and Child Health Research Institute in Petrovsky National Research Centre of Surgery; Federal Research Centre of Nutrition, Biotechnology and Food Safety
Russian Federation

Moscow


Disclosure of interest:

Not declared



Sergey V. Tikhonov
Scientific and Practical Center for Pediatric Psychoneurology; Patrice Lumumba Peoples’ Friendship University of Russia
Russian Federation

Moscow


Disclosure of interest:

Not declared



Rustem F. Tepaev
Sechenov First Moscow State Medical University; Z.A. Bashlyaeva Children’s City Clinical Hospital
Russian Federation

Moscow


Disclosure of interest:

Not declared



Anna Yu. Tomilova
Pirogov Russian National Research Medical University; Federal Research and Clinical Center of Children and Adolescents
Russian Federation

Moscow


Disclosure of interest:

Not declared



Tatyana V. Turti
Pediatrics and Child Health Research Institute in Petrovsky National Research Centre of Surgery; Pirogov Russian National Research Medical University
Russian Federation

Moscow


Disclosure of interest:

Not declared



Viktor A. Tutel’yan
Federal Research Centre of Nutrition, Biotechnology and Food Safety
Russian Federation

Moscow


Disclosure of interest:

Not declared



Anatoly I. Ul’yanin
Sechenov First Moscow State Medical University
Russian Federation

Moscow


Disclosure of interest:

Not declared



Nataliya V. Ustinova
Pediatrics and Child Health Research Institute in Petrovsky National Research Centre of Surgery; Scientific and Practical Center for Pediatric Psychoneurology
Russian Federation

Moscow


Disclosure of interest:

Not declared



Marina V. Fedoseenko
Pediatrics and Child Health Research Institute in Petrovsky National Research Centre of Surgery; Pirogov Russian National Research Medical University
Russian Federation

Moscow


Disclosure of interest:

Not declared



Andrey P. Fisenko
National Medical Research Center for Children’s Health
Russian Federation

Moscow


Disclosure of interest:

Not declared



Anatoly I. Khavkin
Research Clinical Institute of Childhood; Belgorod State National Research University
Russian Federation

Mytishchi, Belgorod


Disclosure of interest:

Not declared



Kamilla E. Efendieva
Pediatrics and Child Health Research Institute in Petrovsky National Research Centre of Surgery; Pirogov Russian National Research Medical University
Russian Federation

Moscow


Disclosure of interest:

Not declared



Ekaterina A. Yablokova
Sechenov First Moscow State Medical University
Russian Federation

Moscow


Disclosure of interest:

Not declared



Sergey P. Yatsyk
Russian Medical Academy of Continuous Professional Education
Russian Federation

Moscow


Disclosure of interest:

Not declared



References

1. Hulst JM, Huysеntruyt K, Gеrasimidis K, et al. A practical approach to idеntifying Pediatric disеasе-associatеd undеrnutrition: a position statеMent from thе ЕSPGHAN spеcial intеrеst group on clinical malnutrition. J Pediatr Gastroenterol Nutr. 2022;74(5): 693–705. doi: https://doi.org/10.1097/MPG.0000000000003437

2. Becker PJ, Nieman Carney L, Corkins MR, et al. Consensus statement of the Academy of Nutrition and Dietetics/American Society for Parenteral and Enteral Nutrition: indicators recommended for the identification and documentation of pediatric malnutrition (undernutrition). J Acad Nutr Diet. 2014;114(12):1988–2000. doi: https://doi.org/10.1016/j.jand.2014.08.026

3. Cederholm T, Barazzoni R, Austin P, et al. ESPEN guidelines on definitions and terminology of clinical nutrition. Clin Nutr. 2017;36(1):49–64. doi: https://doi.org/10.1016/J.CLNU.2016.09.004

4. Kolaček S. Enteral nutrition. World Rev Nutr Diet. 2013; 108:86–90. doi: https://doi.org/10.1159/000351490

5. Suzuki H, Asakawa A, Amitani H, et al. Cancer cachexia-pathophysiology and management. J Gastroenterol. 2013;48(5):574–594. doi: https://doi.org/10.1007/s00535013-0787-0

6. Bhutta ZA, Berkley JA, Bandsma RHJ, et al. Severe childhood malnutrition. Nat Rev Dis Primers. 2017;3:17067. doi: https://doi.org/10.1038/nrdp.2017.67

7. Ivashkin VT, Fomin VV, Tkacheva ON, et al. Small Intestinal Bacterial Overgrowth in Various Specialties of Medical Practice (Literature Review and Expert Council Resolution). Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2024;34(2):14–34. (In Russ). https://doi.org/10.22416/1382-4376-2024-954

8. Keski-Rahkonen A, Ruusunen A. Avoidant-restrictive food intake disorder and autism: epidemiology, etiology, complications, treatment, and outcome. Curr Opin Psychiatry. 2023;36(6):438–442. doi: https://doi.org/10.1097/YCO.0000000000000896

9. Freijer K, van Puffelen E, Joosten KF, et al. The costs of disease related malnutrition in hospitalized children. Clin Nutr ESPEN. 2018;23:228–233. doi: https://doi.org/10.1016/j.clnesp.2017.09.009

10. Suggested citation: United Nations Children’s Fund (UNICEF), World Health Organization, International Bank for Reconstruction and Development/The World Bank. Levels and trends in child malnutrition: key findings of the 2021 edition of the joint child malnutrition estimates. Geneva: World Health Organization; 2021. Available online: https://www.who.int/publications/i/ item/9789240025257. Accessed on August 09. 2026.

11. McCarthy A, Delvin E, Marcil V, et al. Prevalence of Malnutrition in Pediatric Hospitals in Developed and In-Transition Countries: The Impact of Hospital Practices. Nutrients. 2019;11(2):236. doi: https://doi.org/doi.org/10.3390/nu11020236

12. Cahill NE, Murch L, Jeejeebhoy K, et al. When early enteral feeding is not possible in critically ill patients: results of a multicenter observational study. JPEN J Parenter Enteral Nutr. 2011;35(2): 160–168. doi: https://doi.org/10.1177/0148607110381405

13. Dizdar OS, Baspınar O, Kocer D, et al. Nutritional Risk, Micronutrient Status and Clinical Outcomes: A Prospective Observational Study in an Infectious Disease Clinic. Nutrients. 2016;8(3):124. doi: https://doi.org/10.3390/nu8030124

14. Batra A, Beattie RM. Recognising malnutrition in children with neurodisability. Clin Nutr. 2020;39(2):327–330. doi: https://doi.org/10.1016/j.clnu.2019.08.011

15. Gritsinskaya VL, Novikova VP. On the epidemiology of underweight in children and adolescents (systematic review and meta-analysis of scientific publications). Experimental and Clinical Gastroenterology. 2023;215(7):125–135. (In Russ). doi: https://doi.org/10.31146/1682-8658-ecg-215-7-125-135]

16. Bailey RL, West KP Jr, Black RE. The epidemiology of global micronutrient deficiencies. Ann Nutr Metab. 2015; 66(Suppl 2):22. doi: https://doi.org/10.1159/000371618

17. Zvonkova NG. Nedostatochnost’ pitaniya u detei: diagnostika, dietoterapiya i profilaktika v usloviyakh mnogoprofil’nogo statsionara. [dissertation]. Moscow; 2024. 310 p. (In Russ).

18. Strokova TV, Batysheva TT, Pyr’eva EA, et al. Otsenka pishchevogo statusa, sposoby ego korrektsii i printsipy nutritivnoi podderzhki u detei s detskim tserebral’nym paralichom: Teaching and methodological manual. Moscow: Gruppa “Razvitie”; 2023. 120 p. (In Russ).

19. Domperidone (United States: Available via FDA investigational drug [IND] protocol only): Pediatric drug information. In: UpToDate: Website. 2025. Available online: https://www-uptodate-com.libook.xyz/contents/domperidone-united-states-availablevia-fda-investigational-drug-ind-protocol-only-pediatricdrug-information?sectionName=Pediatric&topicId=149360&search=domperidone%20pediatric&usage_type=panel&anchor=F60662610&source=panel_search_result&selectedTitle=1~40&showDrugLabel=true&kp_tab=drug_pediatric&display_rank=1#F60662610. Accessed on Accessed on August 09, 2026. [Content is available after registration.]

20. Bell KL, Samson-Fang L. Nutritional management of children with cerebral palsy. Eur J Clin Nutr. 2013;67(Suppl 2):S13–S16. doi: https://doi.org/10.1038/ejcn.2013.225

21. Titova ON, Taran NN, Strokova TV, et al. Evaluation of the efficacy of using a mixture based on whey protein hydrolysate for nutritional supplementation of children with cerebral palsy. Russian Medical Inquiry. 2020;4(5):282–289. (In Russ). doi: https://doi.org/10.32364/2587-6821-2020-4-5-282-289]

22. Warlow T, Yates J, Taylor N, et al. Gastrointestinal Dystonia in Children and Young People with Severe Neurological Impairment & Palliative Care Needs: A Systematic Review. Children (Basel). 2025;12(10):1359. doi: https://doi.org/10.3390/children12101359

23. Gandaeva LA. Narusheniya nutritivnogo statusa i vozmozhnosti ego korrektsii u detei s kardiomiopatiyami i vrozhdennymi porokami serdtsa, oslozhnennymi khronicheskoi serdechnoi nedostatochnost’yu. [abstract of dissertation]. Moscow; 2016. 24 p. (In Russ).

24. Syitkov VV, Borovik TE, Poddubnyiy IV, et al. Nutritional status and nutritional peculiarities of children with Hirschsprung’s disease in surgical hospital. Pediatria. Journal n.a. G.N. Speransky. 2017;96(5):104–110. (In Russ).

25. Sokolov I. Optimizatsiya nutritivnoi podderzhki u detei s mukovistsidozom. [dissertation]. Moscow; 2021. 193 p. (In Russ).

26. Fedorushkina NA. Nutritivnyi status detei so spasticheskimi formami detskogo tserebral’nogo paralicha. [dissertation]. Moscow; 2023. 171 p. (In Russ).

27. WHO guideline on the prevention and management of wasting and nutritional oedema (acute malnutrition) in infants and children under 5 years. Geneva: World Health Organization; 2023.

28. Watеrlow J.C. Classification and definition of protein-calorie malnutrition. Br Med J. 1972;3(5826):566–569. doi: https://doi.org/10.1136/bmj.3.5826.566

29. Mehta NM, Corkins MR, Lyman B, et al. Defining pediatric malnutrition: A paradigm shift toward etiology-related definitions. JPEN J Parenter Enter Nutr. 2013;37(4):460–481. doi: https://doi.org/10.1177/0148607113479972

30. Becker P, Carney LN, Corkins MR, et al. Consensus statement of the Academy of Nutrition and Dietetics/American Society for Parenteral and Enteral Nutrition: indicators recommended for the identification and documentation of pediatric malnutrition (undernutrition). Nutr Clin Pract. 2015;30(1):147–161. doi: https://doi.org/10.1177/0884533614557642

31. United Nations Children’s Fund (UNICEF), World Health Organization (WHO), International Bank for Reconstruction and Development/The World Bank. Levels and trends in child malnutrition: UNICEF/WHO/World Bank Group Joint Child Malnutrition Estimates: Key findings of the 2023 edition. New York: UNICEF and WHO; 2023.

32. Murray D, Kerr KD, Brunton C, et al. First Step Towards Eliminating Malnutrition: A Proposal for Universal Nutrition Screening in Pediatric Practice. Nutr Diet Suppl. 2021;13:17–24. doi: https://doi.org/10.2147/NDS.S287981

33. Daskalou E, Galli-Tsinopoulou A, Karagiozoglou-Lampoudi T, Augoustides-Savvopoulou P. Malnutrition in Hospitalized Pediatric Patients: Assessment, Prevalence, and Association to Adverse Outcomes. J Am Coll Nutr. 2016;35(4):372–380. doi: https://doi.org/10.1080/07315724.2015.1056886

34. Letter of the Ministry of Health of Russia dated November 21, 2017 No. 15-2/10/2-8090 with methodological recommendations “Otsenka fizicheskogo razvitiya detei i podrostkov”. (In Russ). Доступно по: https://static-0.minzdrav.gov.ru/system/attachments/attaches/000/037/250/original/МРОценкаФиз_развития_детей.pdf. Ссылка активна на 09.08.2026.

35. Cederholm T, Bosaeus I, Barazzoni R, et al. Diagnostic criteria for malnutrition — an ESPEN Consensus Statement. Clin Nutr. 2015;34(3):335–340. doi: https://doi.org/10.1016/j.clnu.2015.03.001

36. Cederholm T, Jensen GL. To create a consensus on malnutrition diagnostic criteria: a report from the Global Leadership Initiative on Malnutrition (GLIM) meeting at the ESPEN Congress 2016. Clin Nutr. 2017;36(1):7–10. doi: https://doi.org/10.1016/j.clnu.2016.12.001

37. WHO. Child Growth Standards. WHO Anthro Survey Analyser and other tools. In: World Health Organization: Official website. Available online: https://www.who.int/tools/child-growth-standards/software. Accessed on August 09, 2026.

38. NICE. Faltering growth: recognition and management of faltering growth in children: NICE Guideline. 27 September 2017. Available online: https://www.nice.org.uk/guidance/ng75/resources/faltering-growth-recognition-and-management-of-faltering-growthin-children-pdf-1837635907525. Accessed on August 09, 2026.

39. Slaughter MH, Lohman TG, Boileau RA, et al. Skinfold equations for estimation of body fatness in children and youth. Hum Biol. 1988;60(5):709–723.

40. Romano C, van Wynckel M, Hulst J, et al. European Society for Paediatric Gastroenterology, Hepatology and Nutrition Guidelines for the Evaluation and Treatment of Gastrointestinal and Nutritional Complications in Children With Neurological Impairment. J Pediatr Gastroenterol Nutr. 2017;65(2):242–264. doi: https://doi.org/10.1097/MPG.0000000000001646

41. Zvonkova NG, Borovik TE, Maslova NA, Fomina MV. Potential of using mid-upper arm circumference as pediatric screening tool for malnutrition. Voprosy detskoi dietologii = Pediatric Nutrition. 2021;19(6): 68–74. (In Russ). doi: https://doi.org/10.20953/17275784-2021-6-68-74

42. Aydın K, Dalgıç B, Kansu A, et al. The significance of MUAC z-scores in diagnosing pediatric malnutrition: A scoping review with special emphasis on neurologically disabled children. Front Pediatr. 2023;11:1081139. doi: https://doi.org/10.3389/fped.2023.1081139

43. Pyrieva EA, Safronova AI, Timoshina MI. Evaluation of the efficacy of MUAC in the diagnosis of malnutrition in children. Voprosy detskoi dietologii = Pediatric Nutrition. 2025;23(1):42–50. (In Russ). doi: https://doi.org/10.20953/1727-5784-2025-1-42-50

44. Liu LF, Roberts R, Moyer-Mileur L, Samson-Fang L. Determination of body composition in children with cerebral palsy: bioelectrical impedance analysis and anthropometry vs dual-energy x-ray absorptiometry. J Am Diet Assoc. 2005;105(5):794–797. doi: https://doi.org/10.1016/j.jada.2005.02.006

45. Nikolaev DV, Smirnov AV, Bobrinskaya IG, Rudnev SG. Bioimpedansnyi analiz sostava tela cheloveka. Moscow: Nauka; 2009. 392 p. (In Russ).

46. Evans DC, Corkins MR, Malonе A, et al. The use of visceral proteins as nutrition markers: an ASPЕN position papеr. Nutr Clin Pract. 2021;36(1):22–28. doi: https://doi.org/10.1002/ncp.10588

47. Physical status: the use and interpretation of anthropometry. Report of a WHO Expert Committee. World Health Organ Tech Rep Ser. 1995;854:1–452.

48. WHO. Child Growth Standards. The WHO Anthro Software. In: World Health Organization: Official website. Available online: https://www.who.int/tools/child-growth-standards/software. Accessed on August 09, 2026.

49. Appendix: Syndrome-specific Growth Charts. In: Brook’s Clinical Pediatric Endocrinology. Brook CGD, Clayton PE, Brown RS, eds. 6th edn. Wiley-Blackwell; 2009. Available online: https://onlinelibrary. wiley.com/doi/pdf/10.1002/9781444316728.app1. Accessed on August 09, 2026.

50. Jensen C. Indications for nutritional assessment in childhood. In: UpToDate: Website. Available online: https://www.uptodate.com/contents/indications-for-nutritional-assessment-inchildhood?search=protein-energy%20deficiency%20children&topicRef=5351&source=related_link#topicGraphics. Accessed on August 09, 2026.

51. Stevenson RD, Conaway M. Growth assessment of children with cerebral palsy: the clinician’s conundrum. Dev Med Child Neurol. 2007;49(3):164. doi: https://doi.org/10.1111/j.14698749.2007.00164.x

52. Brooks J, Day S, Shavеllе R, Strauss D. Low weight, morbidity, and mortality in children with cerebral palsy: new clinical growth charts. Pediatrics. 2011;128(2):е299–е307. doi: https://doi.org/10.1542/peds.2010-2801

53. Zemel BS, Pipan M, Stallings VA, et al. Growth Charts for Children With Down Syndrome in the United States. Pediatrics. 2015;136(5):e1204–e1211. doi: https://doi.org/10.1542/peds.2015-1652

54. Owen E, Williams JE, Davies G, et al. Growth, body composition, and lung function in prepubertal children with cystic fibrosis diagnosed by newborn screening. Nutr Clin Pract. 2020;36(6): 1240–1246. doi: https://doi.org/10.1002/ncp.10604

55. Samson-Fang L, Bell KL. Assessment of growth and nutrition in children with cerebral palsy. Eur J Clin Nutr. 2013;67(Suppl 2): S5–S8. doi: https://doi.org/10.1038/ejcn.2013.223].

56. Bechard LJ, Duggan C, Touger-Decker R, et al. Nutritional status based on body mass index is associated with morbidity and mortality in mechanically ventilated critically ill children in the PICU. Crit Care Med. 2016;44(8):1530–1537. doi: https://doi.org/10.1097/CCM.0000000000001713

57. Hecht C, Weber M, Grote VD, et al. Disease associated malnutrition correlates with length of hospital stay in children. Clin Nutr. 2015;34(1):53–59. doi: https://doi.org/10.1016/j.clnu.2014.01.003

58. Hulst JM, Zwart H, Hop WC, et al. Dutch national survey to test the STRONGkids nutritional risk Screening tool in hospitalized children. Clin Nutr. 2010;29(1):106–111. doi: https://doi.org/10.1016/j.clnu.2009.07.006

59. Zvonkova NG, Borovik TE, Chernikov VV, et al. Adaptation and validation of the STRONGkids nutritional risk screening tool for the Russian language speaking audience. Pediatria. Journal n.a. G.N. Speransky. 2022;101(4):155–164. (In Russ). doi: https://doi.org/10.24110/0031-403X-2022-101-4-155-164

60. Yakovleva MN, Smirnova KI, Lisitsa IA, et al. Laboratory markers of protein and energy insufficiency. Literature review. University Therapeutic Journal (St. Petersburg). 2024;6(1):79–89. (In Russ). doi: https://doi.org/10.56871/UTJ.2024.38.70.007

61. Laboratory and radiologic evaluation of nutritional status in children. In: UpToDate: Website. Available online: https://www.uptodate.com/contents/laboratory-and-radiologic-evaluationof-nutritional-status-in-children?search=protein-energy%20deficiency%20children&topicRef=5358&source=related_link. Accessed on August 09, 2026.

62. Gerasimidis K, Bronsky J, Catchpole A, et al. Assessment and Interpretation of Vitamin and Trace Element Status in Sick Children: A Position Paper From the European Society for Paediatric Gastroenterology Hepatology, and Nutrition Committee on Nutrition. J Pediatr Gastroenterol Nutr. 2020;70(6):873–881. doi: https://doi.org/10.1097/MPG.0000000000002688

63. Hartman C, Shamir R, Simchowitz V, et al. ESPGHAN/ESPEN/ ESPR/CSPEN guidelines on pediatric parenteral nutrition: Complications. Clin Nutr. 2018;37(6 Pt B):2418–2429. doi: https://doi.org/10.1016/j.clnu.2018.06.956

64. Goldstein B, Giroir B, Randolph A, et al. International pediatric sepsis consensus conference: Definitions for sepsis and organ dysfunction in pediatrics. Pediatr Crit Care Med. 2005;6(1):2–8.

65. Weil WB. Fluid and electrolyte metabolism in infants and children: a unified approach. New York: Grune & Stratton; 1977.

66. Chesney CR. The maintenance need for water in parenteral fluid therapy, by Malcolm A. Holliday, MD, and William E. Segar, MD, Pediatrics, 1957;19:823–832. Pediatrics. 1998;102(1 Pt 2):229–230.

67. ESPEN/ESPGHAN Guidelines on paediatric parenteral nutrition. Clin Nutr. 2006;25(2):177–360.

68. Jochum F, Moltu SJ, Senterre T, et al. ESPGHAN/ESPEN/ ESPR/CSPEN guidelines on pediatric parenteral nutrition: Fluid and electrolytes. Clin Nutr. 2018;37(6 Pt B):2344–2353. doi: https://doi.org/10.1016/j.clnu.2018.06.948

69. Rudnev SG, Soboleva NP, Sterlikov SA, et al. Bioimpedansnoe issledovanie sostava tela naseleniya Rossii. Moscow: Editorial and Publishing Department of the Central Research Institute for Health Organization and Informatization; 2014. 493 p. (In Russ).

70. Ivanova IV, Chernaya NL, Mamontova OK. Otsenka zhirovogo komponenta massy tela shkol’nikov s pomoshch’yu portativnogo poluavtomaticheskogo kalipera. Pediatria. Journal n.a. G.N. Speransky. 2011;90(3):34–37. (In Russ).

71. García FАL, Sánchez-Ramírez CА, Newton-Sánchez ÓA, Rojas-Larios F. Correlación entre la plicometría y el análisis de bioimpedancia eléctrica para la evalación de la composición corporal en pacientes en diálisis. Nutr Hosp. 2018;35(1):117–122. doi: https://doi.org/10.20960/nh.1284

72. Inoue T, Wakabayashi H, Kawase F, et al. Diagnostic criteria, prevalence, and clinical outcomes of pediatric sarcopenia: A scoping review. Clin Nutr. 2024;43(8):1825–1843. doi: https://doi.org/10.1016/j.clnu.2024.06.024

73. Lityaeva LA, Kovaleva OV. Otsenka zhirovogo komponenta massy tela shkol’nikov s pomoshch’yu portativnogo poluavtomaticheskogo kalipera. Pediatria. Journal n.a. G.N. Speransky. 2011;90(3):34–37. (In Russ).

74. Peinado Fabregat MI, Gardner RM, Hassan MA, et al. Small Intestinal Bacterial Overgrowth in Children: Clinical Features and Treatment Response. JPGN Rep. 2022;3(2):e185. doi: https://doi.org/10.1097/PG9.0000000000000185

75. Hammer HF, Fox MR, Keller J, et al. European guideline on indications, performance, and clinical impact of hydrogen and methane breath tests in adult and pediatric patients: European Association for Gastroenterology, Endoscopy and Nutrition, European Society of Neurogastroenterology and Motility, and European Society for Paediatric Gastroenterology Hepatology and Nutrition consensus. United European Gastroenterol J. 2022;10(1):15–40. doi: https://doi.org/10.1002/ueg2.12133

76. Maharaj AR, Edginton AN. Examining Small Intestinal Transit Time as a Function of Age: Is There Evidence to Support Age-Dependent Differences among Children? Drug Metab Dispos. 2016;44(7): 1080–1089. doi: https://doi.org/10.1124/dmd.115.068700

77. Bering J, DiBaise JK. Home Parenteral and Enteral Nutrition. Nutrients. 2022;14(13):2558. doi: https://doi.org/10.3390/nu14132558

78. Zaccone V, Santoro L, Guerrieri E, et al. Prevention and treatment of catheter-related venous thrombosis in long-term parenteral nutrition: A SINuC position statement. Front Nutr. 2023;10:1106327. doi: https://doi.org/10.3389/fnut.2023.1106327

79. Metodicheskie rekomendatsii po otsenke kolichestva potreblyaemoi pishchi metodom 24-chasovogo (sutochnogo) vosproizvedeniya pitaniya (Approved by the Deputy Chief State Sanitary Doctor of the Russian Federation. No. С1-19/14-17 dated February 26, 1996). (In Russ).

80. Sorvacheva TN, Martinchik AN, Pyr’eva EA. Kompleksnaya otsenka fakticheskogo pitaniya i nutritivnogo statusa detei. Moscow: State Budgetary Educational Institution of Higher Professional Education Russian Medical Academy of Postgraduate Education; 2013. 74 p. (In Russ).

81. Jonkers CF, Prins F, Van Kempen A, et al. Towards implementation of optimum nutrition and better clinical nutrition support. Clin Nutr. 2001;20(4):361–366. doi: https://doi.org/10.1054/clnu.2001.0470

82. Shang E, Hasenberg T, Schlegel B, et al. An European survey of structure and organisation of nutrition support teams in Germany, Austria and Switzerland. Clin Nutr. 2005;24(6):1005–1013. doi: https://doi.org/10.1016/j.clnu.2005.07.005

83. Saunders J, Smith T, Stroud M. Malnutrition and undernutrition. Medicine. 2015;43(2):112–118. doi: https://doi.org/10.1016/j.mpmed.2014.11.015

84. Bouma S. Diagnosing Pediatric Malnutrition. Nutr Clin Pract. 2017;32(1):52–67. doi: https://doi.org/10.1177/0884533616671861

85. AlQahtani SN, AlGubaisi S, AlHaffaf FA, et al. Nutrition Support Therapy for Hospitalized Children with Malnutrition: A Narrative Review. Healthcare (Basel). 2025;13(5):497. doi: https://doi.org/10.3390/healthcare13050497

86. White E, Mutalib M. Parenteral Nutrition in Pediatric Patients with Neurodisability: Current Perspectives. Pediatric Health Med Ther. 2023;14:11–17. doi: https://doi.org/10.2147/PHMT.S366635

87. Herpertz-Dahlmann B. Treatment of eating disorders in child and adolescent psychiatry. Curr Opin Psychiatry. 2017;30(6):438–445. doi: https://doi.org/10.1097/YCO.0000000000000357

88. Ruth M. Watling The positive impact of dietitians in paediatric health care. Paediatr Child Health. 2009;19(9):400–404.

89. Mechanick JI. Parenteral nutrition formulation: an integral part of the endocrinologist’s metabolic support consultation service. Endocr Pract. 1996;2(3):197–203. doi: https://doi.org/10.4158/EP.2.3.197

90. Tekin H, Tekgül H, Yılmaz S, et al. Prevalence and severity of malnutrition in pediatric neurology outpatients with respect to underlying diagnosis and comorbid nutrition and feeding related problems. Turk J Pediatr. 2018;60(6):709–717. doi: https://doi.org/10.24953/turkjped.2018.06.012

91. Aydin K. Turkish Cerebral Palsy Study Group. A multicenter crosssectional study to evaluate the clinical characteristics and nutritional status of children with cerebral palsy. Clin Nutr ESPEN. 2018;26: 27–34. doi: https://doi.org/10.1016/j.clnesp.2018.05.002

92. Selimoglu MA, Kansu A, Aydogdu S, et al. Nutritional Support in Malnourished Children With Compromised Gastrointestinal Function: Utility of Peptide-Based Enteral Therapy. Front Pediatr. 2021;9:610275. doi: https://doi.org/10.3389/fped.2021.610275

93. Nicholls-Clow R, Simmonds-Buckley M, Waller G. Avoidant/ restrictive food intake disorder: Systematic review and meta-analysis demonstrating the impact of study quality on prevalence rates. Clin Psychol Rev. 2024;114:102502. doi: https://doi.org/10.1016/j.cpr.2024.102502

94. Arcelus J, Mitchell AJ, Wales J, Nielsen S. Mortality rates in patients with anorexia nervosa and other eating disorders. A metaanalysis of 36 studies. Arch Gen Psychiatry. 2011;68(7):724–731. doi: https://doi.org/10.1001/archgenpsychiatry.2011.74

95. Seashore JH. Nutritional support of children in the intensive care unit. Yale J Biol Med. 1984;57(2):111–134.

96. Bekele A, Janakiraman B. Physical therapy guideline for children with malnutrition in low income countries: clinical commentary. J Exerc Rehabil. 2016;12(4):266–275. doi: https://doi.org/10.12965/jer.1632674.337

97. Nassar MF, Abdel-Wahed MA, Abdelhaleem BA, et al. Nutritional rehabilitation of malnourished children detected by Screening Tool for Assessment of Malnutrition in Pediatric: Urban versus rural settings. Clin Nutr ESPEN. 2023;57:749–754. doi: https://doi.org/10.1016/j.clnesp.2023.08.026

98. Steien D, Alexander E, Hager M, et al. Where comfort and nutrition meet: A case series of children with severe neurologic impairment receiving home parenteral nutrition at the end of life. Nutr Clin Pract. 2026;41(2):680–687. doi: https://doi.org/10.1002/ncp.70026

99. Abdelhadi NN, Jaddoua S. Nutrition support therapy prescribing practices in hospice and palliative care units: a retrospective cohort study investigating physician prescribing practices and roles of pharmacists at a tertiary cancer center. J Egypt Natl Canc Inst. 2025;37(1):38. doi: https://doi.org/10.1186/s43046-025-00297-9

100. Smart T. A palliative care perspective on nutritional support. 16 July 2009. In: Aidsmap: Website. Available online: https://www.aidsmap.com/news/jul-2009/palliative-care-perspectivenutritional-support. Accessed on August 09, 2026.

101. Braegger C, Decsi T, Dias JA, et al. Practical approach to paediatric enteral nutrition: a comment by the ESPGHAN committee on nutrition. J Pediatr Gastroenterol Nutr. 2010;51(1):110–122. doi: https://doi.org/10.1097/MPG.0b013e3181d336d2

102. Puntis J, Hojsak I, Ksiazyk J, et al. ESPGHAN/ESPEN/ESPR/ CSPEN guidelines on pediatric parenteral nutrition: Organisational aspects. Clin Nutr. 2018;37(6 Pt B):2392–2400. doi: https://doi.org/10.1016/j.clnu.2018.06.953

103. Norman K, Pichard C, Lochs H, Pirlich M. Prognostic impact of disease — related malnutrition. Clin Nutr. 2008;27(1):5–15. doi: https://doi.org/10.1016/j.clnu.2007.10.007

104. Fouin-Fortunet H, Le Quernec L, Erlinger S, et al. Hepatic alterations during total parenteral nutrition in patients with inflammatory bowel disease: a possible consequence of lithocholate toxicity. Gastroenterology. 1982;82:932–937.

105. Moseley RH. A molecular basis for jaundice in intrahepatic and extrahepatic cholestasis. Hepatology. 1997;26(6):1682–1684. doi: https://doi.org/10.1002/hep.510260645

106. McCallum Z, Bines JE. Enteral Nutrition and Formulas. In: Nutrition in pediatrics. Duggan C, Watkins JB, Koletzko, Walker WA, eds. 5th edn. Shelton, CT: PMPH-USA; 2016. pp. 1023–1034.

107. Perioperatsionnaya nutritivnaya podderzhka: Methodological recommendations. Ministry of Health of Russian Federation; 2021. 40 p. (In Russ).

108. Rukovodstvo po klinicheskomu pitaniyu: Guide. Luft VM, Afonchikov VS, Dmitriev AV, et al. St. Petersburg: Art-Ekspress; 2016. 432 p. (In Russ).

109. Ehnteral’noe i parenteral’noe pitanie: National guide. Saltanov AI, Popova TS, eds. Moscow: GEOTAR-Media; 2014. 814 p. (In Russ).

110. Weimann A, Braga M, Carli F, et al. ESPEN guideline: Clinical nutrition in surgery. Clin Nutr. 2017;36(3):623–650. doi: https://doi.org/10.1016/j.clnu.2017.02.013

111. Parenteral’noe i ehnteral’noe pitanie. Khubutiya MSh, Petrikov SS, Popova TS, eds. 2nd edn., revised and added. Moscow: GEOTAR-Media; 2023. 1168 p. (In Russ).

112. Kolaček S. Enteral nutrition support. In: Pediatric Nutrition in Practice. Koletzko B, Bhutta ZA, Dhansay MA, et al., eds. Basel: Karger; 2022. pp. 240–247.

113. Broekaert IJ, Falconer J, Bronsky J, et al. The Use of Jejunal Tube Feeding in Children: A Position Paper by the Gastroenterology and Nutrition Committees of the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition 2019. J Pediatr Gastroenterol Nutr. 2019;69(2):239–258. doi: https://doi.org/10.1097/MPG.0000000000002379

114. Sion-Sarid R, Cohen J, Houri Z, Singer P. Indirect calorimetry: a guide for optimizing nutritional support in the critically ill child. Nutrition. 2013;29(9):1094–1099. doi: https://doi.org/10.1016/j.nut.2013.03.013

115. Human energy requirements. Scientific background papers from the Joint FAO/WHO/UNU Expert Consultation. October 17-24, 2001. Rome, Italy. Public Health Nutr. 2005;8(7A):929–1228. doi: https://doi.org/10.1079/phn2005778

116. Karst H. Rezensionen: W.N. Schofield, C. Schofield und W.P.T. James: Basal metabolic rate—Review and prediction, together with an annotated bibliography of source material. Suppl. 1/1985 in Human Nutrition: Clinical Nutrition Vol. 39 C. 96 Seiten, John Libbey, London 1985. Die Nahrung. 1987;31(2):188. doi: https://doi.org/10.1002/food.19870310224

117. Henry C. Basal metabolic rate studies in humans: measurement and development of new equations. Public Health Nutrition. 2005;8(7a):1133–1152. doi: https://doi.org/10.1079/PHN2005801

118. Ayers P, Adams S, Boullata J, et al. A.S.P.E.N. parenteral nutrition safety consensus recommendations. JPEN J Parenter Enteral Nutr. 2014;38(3):296–333. doi: https://doi.org/10.1177/0148607113511992

119. Bermudes FM, Maneschy AC, Zanatta CD, et al. Early enteral nutrition therapy and mortality in a pediatric intensive care unit. Rev Assoc Med Bras. 2013;59(6):563–570. doi: https://doi.org/10.1007/s00134-009-1664-4

120. Boullata J.I. Overview of the parenteral nutrition use process. JPEN J Parenter Enteral Nutr. 2012;36(2 Suppl):10–13. doi: https://doi.org/10.1177/0148607111433624

121. CSPEN guidelines for nutrition support in neonates. Working Group Of Pediatrics Chinese Society Of Parenteral And Enteral Nutrition, Working Group Of Neonatology Chinese Society Of Pediatrics, Working Group Of Neonatal Surgery Chinese Society Of Pediatric Surgery. Asia Pac J Clin Nutr. 2013;22(4):655–666. doi: https://doi.org/10.6133/apjcn.2013.22.4.21

122. Tume LN, Valla FV, Joosten K, et al. Nutritional support for children during critical illness: European Society of Pediatric and Neonatal Intensive Care (ESPNIC) metabolism, endocrine and nutrition section position statement and clinical recommendations. Intensive Care Med. 2020;46(3):411–425. doi: https://doi.org/10.1007/s00134-019-05922-5

123. Zarubina VV, Vysokolova OV, Mukhina MA, et al. Oral nutritional supplements in patients with cystic fibrosis: research results. Russian Medicine. 2024;30(6):604–615. (In Russ). doi: https://doi.org/10.17816/medjrf636590

124. Kondratyeva EI, Maksimycheva TYu. Malnutrition in children with cystic fibrosis and new therapeutic possibilities. Voprosy detskoi dietologii = Pediatric Nutrition. 2024;22(6):48–53. (In Russ). doi: https://doi.org/10.20953/1727-5784-2024-6-48-53]

125. Marchand V. Nutrition in neurologically impaired children. Paediatr Child Health. 2009;14(6):395–401.

126. Titova ON, Taran NN, Keleynikova AV, et al. Nutritional status of children with infantile cerebral palsy receiving gastrostomy tube feeding. Voprosy detskoi dietologii = Pediatric Nutrition. 2022;20(2):17–28. (In Russ). doi: https://doi.org/10.20953/1727-5784-2022-2-17-28

127. Johnson TW, Milton DL, Johnson K, et al. Comparison of microbial growth between commercial formula and blenderized food for tube feeding. Nutr Clin Pract. 2019;34(2):257–263. doi: https://doi.org/10.1002/ncp.10226

128. Meyer R, Arpe L, Kansu A, et al. Gastrointestinal changes in paediatric malnutrition that may impact on nutrition choice. Front Pediatr. 2025;13:1523613. doi: https://doi.org/10.3389/fped.2025.1523613

129. Steel C, Wile H, Li O, et al. Understanding the use and tolerance of a pediatric and an adult commercial blenderized enteral formula through real-world data. Nutr Clin Pract. 2023;38(2):449–457. doi: https://doi.org/10.1002/ncp.10905

130. Walker S, Johnson TW, Carter H, et al. Blenderized food tube feeding in very young pediatric patients with special healthcare needs. Nutr Clin Pract. 2024;39(1):202–209. doi: https://doi.org/10.1002/ncp.10975

131. Hamadah HK, Elsaoudi ARF, Faraji MA, et al. Ultrasoundguided post-pyloric feeding tube insertion in peri-operative cardiac infants. Cardiol Young. 2022;32(8):1316–1319. doi: https://doi.org/10.1017/S1047951121004182

132. Phipps LM, Weber MD, Ginder BR, et al. A randomized controlled trial comparing three different techniques of nasojejunal feeding tube placement in critically ill children. JPEN J Parenter Enteral Nutr. 2005;29(6):420–424. doi: https://doi.org/10.1177/0148607105029006420

133. Claiborne MK, Gross T, McGreevy J, et al. Point-of-care ultrasound for confirmation of nasogastric and orogastric tube placement in pediatric patients. Pediatr Emerg Care. 2021;37(12):1611–1615. doi: https://doi.org/10.1097/PEC.0000000000002134

134. Intravenous fluid therapy in children and young people in hospital NICE Guideline, No. 29. London: National Institute for Health and Care Excellence (NICE); 2020.

135. Tepaev RF. Parenteral’noe pitanie v pediatrii i detskoi khirurgii. In: Klinicheskaya dietologiya detskogo vozrasta: Manual for doctors. Borovik TE, Ladodo KS, eds. 2nd edn. Moscow: Meditsinskoe Informatsionnoe Agenstvo; 2015. pp. 557–573. (In Russ).

136. Baker RD, Baker SS, Bojczuk G. Parenteral nutrition in infants and children. Jun 10, 2026. In: UpToDate: Website. Available online: https://www.uptodate.com/contents/parenteral-nutritionin-infants-and-children#. Accessed on August 09, 2026.

137. Douglas I. Hyponatremia: why it matters, how it presents, how we can manage it. Cleve Clin J Med. 2006;73(Suppl 3):S4–S12. doi: https://doi.org/10.3949/ccjm.73.suppl_3.s4

138. Hannon M, Thompson C. Hyponatremia—current treatment strategies and perspectives for the future. US Endocrinology. 2011;07(02):116–120. doi: https://doi.org/10.17925/USE.2011.07.02.116

139. Mihatsch W, Fewtrell M, Goulet O, et al. ESPGHAN/ ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Calcium, phosphorus and magnesium. Clin Nutr. 2018;37(6 Pt B):2360–2365. doi: https://doi.org/10.1016/j.clnu.2018.06.950

140. Domellöf M, Szitanyi P, Simchowitz V, et al. ESPGHAN/ ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Iron and trace minerals. Clin Nutr. 2018;37(6 Pt B):2354–2359. doi: https://doi.org/10.1016/j.clnu.2018.06.949

141. Joosten K, Embleton N, Yan W, et al. ESPGHAN/ESPEN/ ESPR/CSPEN guidelines on pediatric parenteral nutrition: Energy. Clin Nutr. 2018;37(6 Pt B):2309–2314. doi: https://doi.org/10.1016/j.clnu.2018.06.944

142. van Goudoever JB, Carnielli V, Darmaun D, Sainz de Pipaon M. ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Amino acids. Clin Nutr. 2018;37(6 Pt B):2315–2323. doi: https://doi.org/10.1016/j.clnu.2018.06.945

143. de Betue CT, Verbruggen SC, Schierbeek H, et al. Does a reduced glucose intake prevent hyperglycemia in children early after cardiac surgery? A randomized controlled crossover study. Crit Care. 2012;16(5):R176. doi: https://doi.org/10.1186/cc11658

144. Mesotten D, Joosten K, van Kempen A, Verbruggen S. ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Carbohydrates. Clin Nutr. 2018;37(6 Pt B):2337–2343. doi: https://doi.org/10.1016/j.clnu.2018.06.947

145. Verbruggen SC, de Betue CT, Schierbeek H, et al. Reducing glucose infusion safely prevents hyperglycemia in post-surgical children. Clin Nutr. 2011;30(6):786–792. doi: https://doi.org/10.1016/j.clnu.2011.05.011

146. Lapillonne A, Fidler Mis N, Goulet O, et al. ESPGHAN/ ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Lipids. Clin Nutr. 2018;37(6 Pt B):2324–2336. doi: https://doi.org/10.1016/j.clnu.2018.06.946

147. Peterson J, Bihain BE, Bengtsson-Olivecrona G, et al. Fatty acid control of lipoprotein lipase: a link between energy metabolism and lipid transport. Proc Natl Acad Sci U S A. 1990;87(3):909–913. doi: https://doi.org/10.1073/pnas.87.3.909

148. Bronsky J, Campoy C, Braegger C. ESPGHAN/ESPEN/ESPR/ CSPEN guidelines on pediatric parenteral nutrition: Vitamins. Clin Nutr. 2018;37(6 Pt B):2366–2378. doi: https://doi.org/10.1016/j.clnu.2018.06.951

149. Lazarev VV, Tsypin LE, Korsunskii AA, et al. Sovremennye podkhody k parenteral’nomu pitaniyu u detei. Detskaya bol’nitsa. 2007;(2):36–47. (In Russ).

150. Kolaček S, Puntis JWL, Hojsak I, et al. ESPGHAN/ESPEN/ ESPR/CSPEN guidelines on pediatric parenteral nutrition: Venous access. Clin Nutr. 2018;37(6 Pt B):2379–2391. doi: https://doi.org/10.1016/j.clnu.2018.06.952

151. Blaney M, Shen V, Kerner JA, et al. Alteplase for the treatment of central venous catheter occlusion in children: results of a prospective, open-label, single-arm study (The Cathflo Activase PediatricStudy). J Vasc Interv Radiol. 2006;17(11 Pt 1):1745–1751. doi: https://doi.org/10.1097/01.RVI.0000241542.71063.83

152. Lumpkin MM. Safety alert: hazards of precipitation associated with parenteral nutrition. Am J Hosp Pharm. 1994;51(11):1427–1428.

153. Huang L, Li S, Chen J, et al. Efficacy and safety of ursodeoxycholic acid in children with cholestasis: A systematic review and meta-analysis. PLoS One. 2023;18(1):e0280691. doi: https://doi.org/10.1371/journal.pone.0280691

154. Ivashkin VT, Maev IV, Abdulganieva DI, et al. Practical Recommendation of the Scientific community for human microbiome research (CHMR) and the Russian Gastroenterological Association (RGA) on Small Intestinal Bacterial Overgrowth in Adults. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2022;32(3):68–85. (In Russ). doi: https://doi.org/10.22416/1382-4376-2022-32-3-68-85]

155. Mattioli G, Cipriani MS, Barone G, et al. Pediatric nutritional surgery and its implications: results from a unicentric retrospective analysis. Pediatr Surg Int. 2024;40(1):116. doi: https://doi.org/10.1007/s00383-024-05700-5

156. Solomon SM, Kirby DF. The refeeding syndrome: A review. J Parenter Enter Nutr. 1990;14(1):90–97. doi: https://doi.org/10.1177/014860719001400190

157. da Silva JSV, Seres DS, Sabino K, et al. ASPEN Consensus Recommendations for Refeeding Syndrome. Nutr Clin Pract. 2020;35(2):178–195. doi: https://doi.org/10.1002/ncp.10474

158. Corsello A, Trovato CM, Dipasquale V, et al. Refeeding Syndrome in Pediatric Age, An Unknown Disease: A Narrative Review. J Pediatr Gastroenterol Nutr. 2023;77(6):e75–e83. doi: https://doi.org/10.1097/MPG.0000000000003945

159. Obeid OA, Hachem DH, Ayoub JJ. Refeeding and metabolic syndromes: two sides of the same coin. Nutr Diabetes. 2014;4(6):e120. doi: https://doi.org/10.1038/nutd.2014.21

160. Bird RP, Eskin NAM. The emerging role of phosphorus in human health. Adv Food Nutr Res. 2021;96:27–88. doi: https://doi.org/10.1016/bs.afnr.2021.02.001

161. O’Connor G, Nicholls D. Refeeding hypophosphatemia in adolescents with anorexia nervosa. Nutr Clin Pract. 2013;28(3): 358–364. doi: https://doi.org/10.1177/0884533613476892

162. Amanzadeh J, Reilly RF. Hypophosphatemia: an evidencebased approach to its clinical consequences and management. Nat Rev Nephrol. 2006;2(3):136–48. doi: https://doi.org/10.1038/ncpneph0124

163. Demling RH. Nutrition, anabolism, and the wound healing process: an overview. Eplasty. 2009;9:e9.

164. Mehanna H, Nankivell PC, Moledina J, Travis J. Refeeding syndrome – awareness, prevention and management. Head Neck Oncol. 2009;1:4. doi: https://doi.org/10.1186/1758-3284-1-4

165. Reber E, Friedli N, Vasiloglou MF, et al. Management of refeeding syndrome in medical inpatients. J Clin Med. 2019;8(12):2202. doi: https://doi.org/10.3390/jcm8122202

166. Lisitsa IA, Aleksandrovich YuS, Zavyalova AN, et al. Features of refeeding syndrome in pediatric intensive care unit patients (review). Messenger of Anesthesiology and Resuscitation. 2024;21(5):97–107. (In Russ). doi: http://doi.org/10.24884/2078-5658-2024-215-97-107]

167. Yaroshetskiy AI, Konanykhin VD, Stepanova SO, Rezepov NA. Hypophosphatemia and refeeding syndrome in the resumption of nutrition in critical care patients (review). Annals of Critical Care. 2019;(2):82–91. (In Russ). doi: https://doi.org/10.21320/1818474X-2019-2-82-91]

168. Azarova NV, Tepaev RF. Primenenie fosfokreatina v lechenii nevrologicheskikh proyavlenii sindroma vozobnovleniya pitaniya (refeeding-sindroma) u detei: klinicheskii sluchai. In: Sbornik tezisov XXVI Kongressa pediatrov Rossii s mezhdunarodnym uchastiem “Aktual’nye problemy pediatrii”, Moskva, 28 fevralya — 2 marta 2025 g. p. 2. (In Russ). Доступно по: https://pediatr-russia.ru/information/kongressy-i-sezdy-pediatrov/2025-god/Tezisi_2025_fin_ok.pdf. Ссылка активна на 09.08.2026.

169. Achufusi TGO, Sharma A, Zamora EA, Manocha D. Small Intestinal Bacterial Overgrowth: Comprehensive Review of Diagnosis, Prevention, and Treatment Methods. Cureus. 2020;12(6):e8860. doi: https://doi.org/10.7759/cureus.8860

170. WHO. Management Of Severe Malnutrition: A Manual for Physicians and Other Senior Health Workers. Geneva: World Health Organization; 1999.

171. Crookston BT, Penny ME, Alder SC, et al. Children who recover from early stunting and children who are not stunted demonstrate similar levels of cognition. J Nutr. 2010;140(11):1996–2001. doi: https://doi.org/10.3945/jn.109.118927

172. Pulakka A, Ashorn U, Cheung YB, et al. Effect of 12-month intervention with lipid-based nutrient supplements on physical activity of 18-month-old Malawian children: a randomised, controlled trial. Eur J Clin Nutr. 2015;69(2):173–178. doi: https://doi.org/10.1038/ejcn.2014.138

173. Bhujade R, Mishra BN, Ibrahim T, et al. Can Sever Acute Malnourished children be effectively rehabilitated physically, biochemically and developmentally at nutritional rehabilitation centers: A follow up study from Ujjain. J Family Med Prim Care. 2021;10(1):343–349. doi: https://doi.org/10.4103/jfmpc.jfmpc_1268_20

174. Daniel AI, Bandsma RH, Lytvyn L, et al. Psychosocial stimulation interventions for children with severe acute malnutrition: A systematic review. J Glob Health. 2017;7(1):010405. doi: https://doi.org/10.7189/jogh.07.010405

175. Brief Stimulation Therapy for Malnourished Children. Available online: https://www.studocu.com/row/document/kenya-medical-training-college/kenya-registered-communityhealth-nursing/brief-stimulation-therapy-for-malnourishedchildren-eng/100656280. Accessed on August 09, 2026.

176. World Health Organization. WHO guideline on the prevention and management of wasting and nutritional oedema (acute malnutrition) in infants and children under 5 years. 29 December 2023. Available online: https://files.magicapp.org/guideline/a3fe934f-6516-460d-902fe1c7bbcec034/published_guideline_7330-1_1.pdf. Accessed on August 09, 2026.

177. Okala SG, Darboe MK, Sosseh F, et al. Impact of nutritional supplementation during pregnancy on antibody responses to diphtheria-tetanus-pertussis vaccination in infants: A randomised trial in The Gambia. PLoS Med. 2019;16(8):e1002854. doi: https://doi.org/10.1371/journal.pmed.1002854

178. Zimmermann P, Curtis N. Factors That Influence the Immune Response to Vaccination. Clin Microbiol Rev. 2019;32(2):e00084-18. doi: https://doi.org/10.1128/CMR.00084-18

179. Guo SM, Roche AF, Fomon SJ, et al. Reference data on gains in weight and length during the first two years of life. J Pediatr. 1991;119(3):355–362. doi: https://doi.org/10.1016/s00223476(05)82045-1

180. World Health Organization. Child growth standards. Weight velocity. Available online: https://www.who.int/tools/child-growth-standards/standards/weight-velocity. Accessed on August 09, 2026.

181. Frisancho AR. New norms of upper limb fat and muscle areas for assessment of nutritional status. Am J Clin Nutr. 1981;34(11):2540–2545. doi: https://doi.org/10.1093/ajcn/34.11.2540

182. Stеvеnson RD. Usе of segmental measure to estimate stature in children with cerebral palsy. Arch Pеdiatr Adolеsc Med. 1995;149(6):658–662. doi: https://doi.org/10.1001/ARCHPEDI.1995.02170190068012

183. Budka-Chrzeszczyk A, Szlagatys-Sidorkiewicz A, Bień E, et al. Managing Undernutrition in Pediatric Oncology: A Consensus Statement Developed Using the Delphi Method by the Polish Society for Clinical Nutrition of Children and the Polish Society of Pediatric Oncology and Hematology. Nutrients. 2024;16(9):1327. doi: https://doi.org/10.3390/nu16091327

184. Normy fiziologicheskikh potrebnostei v ehnergii i pishchevykh veshchestvakh dlya razlichnykh grupp naseleniya Rossiiskoi Federatsii: Methodological recommendations. Moscow: Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing; 2021. 72 p. (In Russ).

185. Titova ON. Izuchenie pishchevogo statusa i razrabotka spetsializirovannykh ratsionov pitaniya u detei s detskim tserebral’nym paralichom. [abstract of dissertation. Moscow; 2024. 24 p. (In Russ).

186. Kraft MD, Btaiche IF, Sacks GS. Review of the refeeding syndrome. Nutr Clin Pract. 2005;20(6):625–633. doi: https://doi.org/10.1177/0115426505020006625


Review

For citations:


Alekseeva A.A., Baranov A.A., Batysheva T.T., Belyaeva I.A., Borovik T.E., Tatyana B.V., Bykova O.V., Gordeeva O.B., Guzeva V.I., Gureev S.A., Gurova M.M., Gusev A.A., Guseva I.M., Zavyalova A.N., Zvonkova N.G., Ivardava M.I., Ivashkin V.T., Kaytukova E.V., Klimov Yu.A., Komarova E.V., Lukoyanova O.L., Makarova S.G., Naletov A.V., Namazova-Baranova L.S., Nikityuk D.B., Novikova V.P., Pavlovskaya E.V., Platonova M.M., Polevichenko E.V., Poluektova E.A., Pyr’eva E.A., Safronova A.I., Selimzyanova L.R., Skvortsova V.A., Sokolov I., Sorvacheva T.N., Starodubova A.V., Strokova T.V., Surkov A.N., Syt’kov V.V., Taran N.N., Tikhonov S.V., Tepaev R.F., Tomilova A.Yu., Turti T.V., Tutel’yan V.A., Ul’yanin A.I., Ustinova N.V., Fedoseenko M.V., Fisenko A.P., Khavkin A.I., Efendieva K.E., Yablokova E.A., Yatsyk S.P. Current Clinical Guidelines for the Management of Children Over One Year of Age with Malnutrition (Protein-Energy Malnutrition). Pediatric pharmacology. 2026;23(4):400-455. (In Russ.) https://doi.org/10.15690/pf.v23i4.3088

Views: 67

JATS XML

ISSN 1727-5776 (Print)
ISSN 2500-3089 (Online)