ERYTHROCYTE AND RETICULOCYTE INDICES IN PATIENTS WITH INFLAMMATORY DISEASES OF DIVERSE GENESIS
https://doi.org/10.15690/pf.v9i6.528
Abstract
Use of the latest blood analyzers with a capacity of differentiated determination of reticulocyte and erythrocyte blood indices in modern diagnostic service is an important addition to detection of anemia syndrome. Generally used standard blood indices in form of a number of erythrocytes and hemoglobin level do not reflect pathophysiological changes leading to anemia development. Flow cytometry methods in modern blood analyzers favor a better evaluation of erythropoiesis by determining several reticulocyte parameters. These studies are important for detection of anemia, especially of anemia of chronic disease. As different mechanisms of pathological iron metabolism changes — deficiency, accessibility and reutilization derangement — may be observed at anemia syndrome, it is necessary to additionally determine the level of inflammatory markers in blood serum in order to choose a correct treatment tactics.
About the Authors
O. B. Gordeeva
Scientific Center of Children’s Health, Moscow, Russian Federation
Russian Federation
Russian Federation
V. V. Botvinyeva
Scientific Center of Children’s Health, Moscow, Russian Federation
Russian Federation
Russian Federation
L. S. Namazova-Baranova
Scientific Center of Children’s Health, Moscow, Russian Federation
I.M. Sechenov First Moscow State Medical University, Russian Federation
N.I. Pirogov Russian National Research Medical University, Moscow, Russian Federation
Russian Federation
Russian Federation
References
1. Баранов А. А., Семикина Е. Л., Мельничук О. С., Гордеева О. Б., Намазова-Баранова Л. С., Морозова Н. А., Кожевникова О. В., Геворкян А. К., Маянский Н. А. Показатели ретикулоцитарных индексов у здоровых детей. Вопросы диагностики в педиатрии. 2010; 2 (4): 17–21.
2. Buttarello M., Temporin V., Ceravolo R. The new reticulocyte parameter (Ret-Y) of the Sysmex XE 2100: its use in the diagnosis and monitoring of posttreatment sideropenic anemia. Am J Clin Pathol. 2004; 121: 489–495.
3. Mast A. E., Blinder M. A., Dietzen D. J. Reticulocyte hemoglobin content. Am J Hematol. 2008; 83: 307–310.
4. Дворецкий Л. И. Анемии: стратегия и тактика диагностического поиска. Справочник поликлинического врача. 2002; 2 (6): 12–15. 5. Луговская С. А., Почтарь М. Е. Ретикулоциты. М., 2006. 60 с.
Review
For citations:
Gordeeva O.B., Botvinyeva V.V., Namazova-Baranova L.S. ERYTHROCYTE AND RETICULOCYTE INDICES IN PATIENTS WITH INFLAMMATORY DISEASES OF DIVERSE GENESIS. Pediatric pharmacology. 2012;9(6):110-112. (In Russ.) https://doi.org/10.15690/pf.v9i6.528
Views:
1086
Email this article 