Preview

Pediatric pharmacology

Advanced search

OMEGA-3 IN PEDIATRIC PRACTICE

https://doi.org/10.15690/pf.v9i6.524

Abstract

The article is dedicated to omega-3 polyunsaturated fatty acids, which are found in several marine and plant oils. The author emphasizes that, being irreplaceable, these fatty acids should enter the body with food. Omega-3 regulate lipid exchange, balance functions of immune, nervous and cardiovascular systems, provide generation of prostaglandins, reduce thrombocyte aggregation, are a structural substance of brain and retina. In case of insufficient consumption of food containing omega-3, their dotation in the form of drugs is necessary. The importance of these compounds for maturation and correct functioning of vital systems both in unborn and newborn children is particularly noted.

About the Author

M. I. Ivardava
Scientific Center of Children’s Health, Moscow, Russian Federation
Russian Federation


References

1. Конь И. Я. Жиры и жирные кислоты. В кн.: Руководство по детскому питанию. Под ред. В. А. Тутельяна, И. Я. Коня. М.: МИА. 2009. С. 71–88.

2. Левачев М. М. Значение жира в питании здорового и больного человека: Справочник по диетологии. Под ред. В. А. Тутельяна, М. А. Самсонова. М.: Медицина. 2002. С. 25–32.

3. Koletzko B., Agostoni C., Carlson S. E., Clandinin T., Hornstra G., Neuringer M., Uauy R., Yamashiro Y., Willatts P. Long chain polyunsaturated fatty acids (LC-PUFA) and perinatal development. Acta Paediatr. 2001; 90: 460–464.

4. McCann J. C., Ames B. N. Is docosahexaeboic acid, an -3 longchain polyunsaturated fatty acid required for development of normal brain function? Am J Clin Nutr. 2005; 82: 281–295.

5. Cockburn F. Neonatal brain and dietary lipids. Arch Dis Child, Fetal and Neonatal. 1994; 70 (1): F1–F2.

6. Agostoni C. Role of long- chain polyunsaturated fatty acids in the first year of life. J Pediatr Gastroenterol Nutr. 2008; 47 (Suppl. 2): 41–44.

7. Innis S. M. Human milk and formula fatty acids. J Pediatrics. 1993; 123: 386–390.

8. Громова О. А., Торшин И. Ю., Сухих Г. Т., Баранов А. А., Прилепская В. Н., Тетруашвили Н. К., Уварова Е. В. Роли различных форм омега-3 ПНЖК в акушерстве и неонатологии. Публикация в рамках реализации национального проекта «Здоровье». М., 2009. 64 с.

9. Martinez M. Tisue levels of polyunsaturated fatty acids during early human development. J Pediatr. 1992; 120: 129–138.

10. Makrides M., Gibson R. Are long-chain polyunsaturated fatty acids essential nutrients in infancy? Lancet. 1995; 345: 1463–1468.

11. Волосовец А. П., Кривопустов С. П. Инсульт головного мозга и инфаркт миокарда у детей: современный взгляд на проблему. Здоровье ребенка. 2006; 2 (2): 12–20.

12. Ryan A. S., Astwood J. D., Gautier S., Kuratko C. N., Nelson E. B., Salem N.Jr. Effects of long-chain polyunsaturated fatty acid supplementation on neurodevelopment in childhood: a review of human studies. Prostaglandins Leukot Essent Fatty Acids. 2010; 82 (4–6): 305–14.

13. Kirby A., Woodward A., Jackson S., Wang Y., Crawford M. A. A double-blind, placebo-controlled study investigating the effects of omega-3 supplementation in children aged 8–10 years from a mainstream school population. Res Dev Disabil. 2010; 31 (3): 18–30.

14. Innis S. M. Dietary (n-3) fatty acids and brain development. J Nutr. 2007; 137 (4): 855–9.

15. Cohen J. T., Bellinger D. C., Connor W. E., Shaywitz B. A. A quantitative analysis of prenatal intake of n-3 polyunsaturated fatty acids and cognitive development. Am J Prev Med. 2005; 29 (4): 366–74.


Review

For citations:


Ivardava M.I. OMEGA-3 IN PEDIATRIC PRACTICE. Pediatric pharmacology. 2012;9(6):92-64. (In Russ.) https://doi.org/10.15690/pf.v9i6.524

Views: 995


ISSN 1727-5776 (Print)
ISSN 2500-3089 (Online)