ETIOLOGY, CLINICAL MANIFESTATIONS, TREATMENT AND PREVENTION OF TICK-BORNE ENCEPHALITIS
https://doi.org/10.15690/pf.v10i2.642
Abstract
At present, tick-borne encephalitis is registered in Siberia, Far East, Urals, Belarus and central regions of Russia. The viral infection has also been recently revealed among the population of the previously problem free regions: Penza, Yaroslavl, Magadan, Kamchatka, Moscow and Ivanovo. The disease manifests itself in various forms: febrile, meningeal, meningoencephalitic etc. The disease prognosis is favorable in case of a meningeal or febrile form, but significantly worse in case of a meningoencephalitic form – fatal outcomes take place in 25-30% of cases. Residuals in the form of convulsive hyperkinetic syndrome may remain in some patients even if the treatment started in time. Active immunization is the primary tick-borne encephalitis prevention.
About the Authors
A. G. Gaivoronskaya
Scientific Center of Children’s Health, Moscow, Russian Federation
Russian Federation
PhD, pediatrician-immunologist of the department for children with health condition deviations at the FSBI RAMS “SCCH” research institute of preventive pediatrics and medical rehabilitation
Russian Federation
PhD, pediatrician-immunologist of the department for children with health condition deviations at the FSBI RAMS “SCCH” research institute of preventive pediatrics and medical rehabilitation
M. G. Galitskaya
Scientific Center of Children’s Health, Moscow, Russian Federation
Russian Federation
Russian Federation
L. S. Namazova-Baranova
Scientific Center of Children’s Health, Moscow, Russian Federation
Sechenov First Moscow State Medical University, Russian Federation
Pirogov Russian National Research Medical University, Moscow
Russian Federation
Russian Federation
References
1. Uchaikin V.F., Shamsheva O.V. Vaktsinoprofilaktika. Nastoyashchee i budushchee [Preventive Vaccination. Present and Future]. Moscow, 2001. pp. 165–166.
2. Korotyaev A.I., Babichev S.A. Flavivirusy. Meditsinskaya mikrobiologiya, immunologiya i virusologiya [Flaviviruses. Medical Microbiology, Immunology and Virology]. St. Petersburg, 2002. pp. 302–304.
3. Ratnikova L.I., Ter-Bagdasaryan L.V., Mironov I.L. Epidemiologiya infektsionnykh boleznei – Epidemiology of infectious diseases. 2002; 5: 41–46.
4. Medunitsin I.V. Vaktsinologiya [Vaccinology]. Moscow, Triada-Kh. 2004. S. 242–243.
5. Ammosov A.D. Kleshchevoi entsefalit. Informatsionno-metodicheskoe posobie [Tick-borne Encephalitis. Informational Handbook]. Kol'tsovo, 2006. pp. 6–9, 69–70, 92.
6. Pogodina V.V., Frolova M.P., Erman B.A. Khronicheskii kleshchevoi entsefalit [Chronic Tick-borne Encephalitis]. Novosibirsk, Nauka. 1986.
7. Leonova G. N., Maistrovskaya O.S., Borisevich V.B. Voprosy virusologii – Problems of virology. 1996; 6: 260–263.
8. Ierusalimskii A.P. Kleshchevoi entsefalit. Rukovodstvo dlya vrachei[Tick-borne Encephalitis. Guide for Physicians]. Novosibirsk, 2001.
9. Mikhailova L.G. Epidemiologiya i vaktsinoprofilaktika – Epidemiology and vaccination. 2004; 1: 35–36.
10. Onishchenko G.G. Zabolevaemost' kleshchevym entsefalitom v Rossiiskoi Federatsii. Epidemiologicheskaya obstanovka i strategiya bor'by s kleshchevym entsefalitom na sovremennom etape [Tick-borne Encephalitis Morbidity in the Russian Federation. Epidemiological Situation and Strategy against Tick-borne Encephalitis at the Present Stage]. Moscow, 2003. pp. 5–6.
11. Borisov V.A., Yushchuk N.D., Malov I.V., Aitov K.A. Epidemiologiya infektsionnykh boleznei – Epidemiology of infectious diseases. 2000; 2: 43–47.
12. Shapoval A.N. Meditsinskaya gazeta – Medical newspaper. 1994; 50.
13. Kleshchevoi entsefalit. Pod redaktsiei Yu.V. Lobzina, S.S. Kozlova, A.P. Uskova. Rukovodstvo po infektsionnym boleznyam s atlasom infektsionnoi patologii [Tick-borne Encephalitis. Edited by Yu.V. Lobzin, S.S. Kozlov, A.P. Uskov. Guideline in Infectious Diseases and Atlas of Infectious Pathologies]. Moscow, 2000. pp. 163–170.
14. Pokrovskii V.I., Loban K.M. Rukovodstvo po infektsionnym boleznyam [Guideline in Infectious Diseases]. Moscow, Meditsina, 1986.
15. Zhukova N.G., Lukashova L.V., Dobkina M.N., Lepikhin A.V. Meditsina v Kuzbasse – Kuzbass medicine. 2008; 5: 53–58.
16. Zlobin V.I., Gorin O.Z. Kleshchevoi entsefalit [Tick-borne Encephalitis]. Novosibirsk, Nauka, 1996.
17. Pogodina V.V. Kleshchevoi entsefalit: reshennye i nereshennye problemy [Tick-borne Encephalitis: Solved and Unsolved Issues]. Materialy 9-go S"ezda vserossiiskogo nauchno-prakticheskogo obshchestva epidemiologov, mikrobiologov i parazitologov (Proceedings of the 9th Congress of the All-Russian Scientific Society Epidemiologists, Microbiologists and Parasitologists). Moscow, 2007. pp. 217–218.
18. Morgatskii N.V. Vozrastnaya kliniko-immunologicheskaya kharakteristika kleshchevogo entsefalita u detei. Avtoref. dis. … kand. med. nauk [Age, Clinical and Immunological Characteristics of Tick-borne Encephalitis in Children. Author’s abstract]. St. Petersburg, 2006.
19. Khaitov R.M., Pinegin B.V. Immunologiya – Immunology. 2000; 1: 61–64.
20. Chernitsyna L.O., Epikhina T.I., Lipatnikova S.V., Alekseeva N.A., Grishaeva O.N., Grishaev M.P., Ammosov A.D., Ierusalimskii A.P. Ispol'zovanie v klinicheskoi praktike vyyavleniya RNK virusa kleshchevogo entsefalita metodom PTsR dlya diagnostiki ostrykh i khronicheskikh form kleshchevogo entsefalita [PCR Method as a Diagnostic Technique to Define Tick-borne Encephalitis RNA Phage and Treatment of Acute and Chronic Forms of Tick-borne Encephalitis in Human]. Tez. dokl. nauchnoi konferentsii «Problemy infektsionnoi patologii v regionakh Sibiri, Dal'nego Vostoka i Krainego Severa. 10–11 aprelya 1998 g (Proc. of Scientific Conference "Problems of Infectious Pathology in Regions of Siberia, the Far East and the Far North. April 10-11, 1998). Novosibirsk, 1998. pp. 20–21.
21. Topychkanova N.G., Rukavishnikov M.Yu., Grishaeva O.N. Byulleten' «Novosti «Vektor-Best» - Bulletin “Vektor-Best News”. 1999; 11: 4–6.
22. Stronin O.V., Podoplekina L.E., Chernyi N.B. Rezul'taty kompleksnogo primeneniya preparatov diagnostiki kleshchevogo entsefalita i analiz mekhanizmov otdel'nykh reaktsii [Results of Complex Application of Tick-borne Encephalitis Diagnosis Methods and Analysis of the Mechanisms of Individual Reactions]. Tez. dokl. nauchnoi konferentsii «Problemy infektsionnoi patologii v regionakh Sibiri, Dal'nego Vostoka i Krainego Severa. 10–11 aprelya 1998 g (Proc. of Scientific Conference "Problems of Infectious Pathology in Regions of Siberia, the Far East and the Far North. April 10-11, 1998). Novosibirsk, 1998. pp. 72–73.
23. Pediatriya: Rukovodstvo. Pod red. R.E. Bermana, V.K. Vogana [Pediatrics: Guideline. Edited by R.E. Berman, V.K. Vogan]. Moscow, 1992. pp. 47–51.
24. Caldan I.P., Preider V.P., Bezrukov G.V. Epidemiologiya infektsionnykh boleznei – Epidemiology of infectious diseases. 2000; 6: 14–15.
25. Immunoprofilaktika-2011. Spravochnik. 11-e izd., dop. Pod red. V.K. Tatochenko i N.A. Ozeretskovskogo [Immunoprophylaxis-2011. Guideline. 11th edition, enlarged. Edited by V.K. Tatochenko and N.A. Ozeretskovskii]. Moscow, 2011. pp. 84–85.
26. Baranov A.A., Namazova-Baranova L.S., Galitskaya M.G. Bolezni detskogo vozrasta ot A do Ya. Immunoprofilaktika u detei. Chast' I. Vaktsinoprofilaktika u detei [Child Diseases from A to Z. Immunoprophylaxis in Children. Chapter 1. Preventive Vaccination in Children]. Moscow, 2012. pp. 38–40.
27. Pavlenko E.V., Leonova G.N., Maistrovskaya O.S. Dal'nevostochnyi zhurnal infektsionnoi patologii – Far East journal of infectious pathology. 2007; 11: 56–62.
28. Pavlenko E.V., Leonova G.N., Maistrovskaya O.S., Krylova N.V. Infektsionnye bolezni – Infectious diseases. 2011; 9 (2): 39–44.
29. Kunz C. TBE vaccination and the Austrian experience. Vaccine. 2003; 21: 50–55.
Review
For citations:
Gaivoronskaya A.G., Galitskaya M.G., Namazova-Baranova L.S. ETIOLOGY, CLINICAL MANIFESTATIONS, TREATMENT AND PREVENTION OF TICK-BORNE ENCEPHALITIS. Pediatric pharmacology. 2013;10(2):34-39. https://doi.org/10.15690/pf.v10i2.642
Views:
1295
Email this article 