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Polypharmacy in Infectious Mononucleosis Management: Case Series

https://doi.org/10.15690/pf.v19i5.2462

Abstract

Background. Infectious mononucleosis is acute viral disease that often forces pediatricians, especially in outpatient departments, to prescribe antibiotics. However, viral infections even with prolonged fever and marked intoxication symptoms do not require antibacterial therapy. Unreasonable antibiotics’ administration leads to increase in antibiotic resistance, increase of treatment cost, and development of incorrect therapy understanding in patients. Clinical case description. The authors presented 3 clinical cases of infectious mononucleosis with typical course in children. All patients were unreasonably administered antibacterial therapy with three or more drugs in absence of any clinical and laboratory signs of bacterial infection. Conclusion. Patients with infectious mononucleosis do not require antibacterial therapy due to viral origin of the disease, regardless disease course duration and severity, except the cases with confirmed comorbid bacterial infection.

About the Authors

Artem A. Ivanov
Morozov Children’s City Hospital
Russian Federation

MD

4 Dobryninskiy pereulok, 1/9, Moscow, 119049


Disclosure of interest:

Not declared.



Tatiana V. Kulichenko
Pirogov Russian National Research Medical University
Russian Federation

MD, PhD, Professor of the RAS

eLibrary SPIN: 9054-4560

Moscow


Disclosure of interest:

Not declared.



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Review

For citations:


Ivanov A.A., Kulichenko T.V. Polypharmacy in Infectious Mononucleosis Management: Case Series. Pediatric pharmacology. 2022;19(5):412-416. (In Russ.) https://doi.org/10.15690/pf.v19i5.2462

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ISSN 1727-5776 (Print)
ISSN 2500-3089 (Online)