EFFICACY AND FINANCIAL VIABILITY OF PRIMARY PREVENTION OF ATOPIC DERMATITIS: PROTEIN-HYDROLYSATE-BASED FORMULAE
https://doi.org/10.15690/pf.v10i4.754
Abstract
Primary prevention of allergy is an attractive aim due to high social, economic burden and increasing prevalence of allergic diseases. The up-to-date data strongly support the use of partially hydrolyzed whey formula for primary prevention of atopic dermatitis. This approach is effective and cost-saving both from societal and governmental health service perspectives. Pediatricians as well as parents of high risk children should be strictly aware of these data. Because of cost-saving effect of partially hydrolyzed whey formula governmental health service administrations should develop programs for primary prevention of atopic dermatitis with free supply of high risk children with this nutrition for first months of life.
About the Authors
L. M. OgorodovaRussian Federation
F. I. Petrovskii
Russian Federation
PhD, head of the pharmacology and clinical pharmacology department with a course of allergology and clinical immunology at the Khanty-Mansiysk State Medical Academy
I. A. Deev
Russian Federation
Y. A. Petrovskaya
Russian Federation
References
1. Огородова Л. М., Федорова О. С., Петровская Ю. А., Петровский Ф. И. Эффективность первичной профилактики бронхиальной астмы. Рос. вест. перинатологии и педиатрии. 2003; 6: 27–30.
2. Аллергия у детей: от теории к практике. Под ред. Л. С. Намазовой-Барановой. М.: Союз педиатров России. 2010.
3. Toit G., Lack G. Can Food Allergy Be Prevented? The Current Evidence. Pediatr Clin N Am. 2011; 58: 481–509.
4. Likura Y., Naspitz C. K., Mikawa H. et al. Prevention of asthma by ketotifen in infants with atopic dermatitis. Ann Allergy. 1992; 68 (3): 233–236.
5. Diepgen T. L. Long-term treatment with cetirizine of infants with atopic dermatitis: a multi-country, double-blind, placebocontrolled trial (the ETAC trial) over 18 months. Pediatric Allergy and Immunology. 2002; 13 (4): 278–86.
6. Alexander D., Cabana M. Partially Hydrolyzed 100% Whey Protein Infant Formula and Reduced Risk of Atopic Dermatitis: A Meta-analysis. JPGN. 2010; 50: 422–430.
7. Геворкян А.К. Применение аминокислотной смеси у больной с непереносимостью коровьего молока. Педиатрическая фармакология. 2008; 5 (4): 37–39.
8. Murch S.H., Намазова Л.С., Боровик Т.Э. Эффективность смесей, основанных на аминокислотах, в обеспечении симптомов аллергии к коровьему молоку: систематический обзор. Педиатрическая фармакология. 2008; 5 (3): 32–38.
9. von Berg A., Koletzko S., Grubl A. et al. The effect of hydrolyzed cow’s milk formula for allergy prevention in the first year of life: The German Infant Nutritional Intervention Study, a randomized doubleblind trial. J Allergy Clin Immunol. 2003; 111: 533–40.
10. von Berg A., Filipiak-Pittroff B., Kramer U. et al. Preventive effect of hydrolyzed infant formulas persists until age 6 years: Long-term results from the German Infant Nutritional Intervention Study (GINI). J Allergy Clin Immunol. 2008; 121: 1442–7.
11. von Berg A., Filipiak-Pittroff B., Kramer U. et al. Allergies in high-risk schoolchildren after early intervention with cow’s milk protein hydrolysates: 10-year results from the German Infant Nutritional Intervention (GINI) study. J Allergy Clin Immunol. 2013 Mar 15. [Epub ahead of print].
12. Mertens J., Stock S., Lungen M. et al. Is Prevention of Atopic Eczema with Hydrolyzed Formulas Cost-Effective? A Health Economic Evaluation from Germany. Pediatr Allergy Immunol. 2012; 23: 597–604.
13. Огородова Л. М., Деев И. А., Деева Е. В., Петровский Ф. И., Бычков ская С. В., Голосова Т. Г., Казакевич Н. В., Коростовцев Д. С., Липина В. Р., Сидоренко И. В., Смирнов Н. А., Черняк Б. А. Резуль таты национального многоцентрового клинико-эпидемиологического исследования атопического дерматита у детей. Аллергология. 2006; 1: 3–9.
14. Moro G., Arslanoglu S., Stahl B. et al. A mixture of prebiotic oligosaccharides reduces the incidence of atopic dermatitis during the first six months of age. Arch Dis Child. 2006; 91: 814–819.
15. Arslanoglu S., Moro G., Schmitt J. et al. Early Dietary Intervention with a Mixture of Prebiotic Oligosaccharides Reduces the Incidence of Allergic Manifestations and Infections during the First Two Years of Life. J Nutr. 2008; 138: 1091–1095.
16. Arslanoglu S., Moro G. E., Boehm G. et al. Early neutral prebiotic oligosaccharide supplementation reduces the incidence of some allergic manifestations in the first 5 years of life. J Biol Regul Homeost Agents. 2012; 26 (3 Suppl.): 49–59.
17. Lenoir-Wijnkoop I., van Aalderen W., Boehm G. et al. Costeffectiveness model for a specific mixture of prebiotics in The Netherlands. Eur J Health Econ. 2012; 13: 101–110.
18. Greer F., Sicherer S., Burks W. Effects of Early Nutritional Interventions on the Development of Atopic Disease in Infants and Children: The Role of Maternal Dietary Restriction, Breastfeeding, Timing of Introduction of Complementary Foods, and Hydrolyzed Formulas. Pediatrics. 2008; 121: 183–91.
19. Burks W., Tang M., Sicherer S. et al. ICON: Food allergy. J Allergy Clin Immunol. 2012; 129: 906–20.
20. Koletzko S., Niggemann B., Arato A. et al. Diagnostic Approach and Management of Cow’s-Milk Protein Allergy in Infants and Children: ESPGHAN GI Committee Practical Guidelines. JPGN. 2012; 55: 221–229.
21. Rzehak P., Sausenthaler S., Koletzko S. et al. Short- and longterm effects of feeding hydrolyzed protein infant formulas on growth at _ 6 y of age: results from the German Infant Nutritional Intervention Study. J Clin Nutr. 2009; 89: 1846–56.
Review
For citations:
Ogorodova L.M., Petrovskii F.I., Deev I.A., Petrovskaya Y.A. EFFICACY AND FINANCIAL VIABILITY OF PRIMARY PREVENTION OF ATOPIC DERMATITIS: PROTEIN-HYDROLYSATE-BASED FORMULAE. Pediatric pharmacology. 2013;10(4):46-51. (In Russ.) https://doi.org/10.15690/pf.v10i4.754