Loop tubulopathies: Bartter’s syndrome
Alexander A. Baranov,
Leyla S. Namazova-Baranova,
Tatyana V. Sergeeva,
Olga V. Chumakova,
Svetlana S. Paunova,
Nurali Z. Zokirov,
Olga V. Komarova,
Tea V. Margieva,
Vladimir K. Tatochenko,
Maya D. Bakradze,
Elena N. Tsygina,
Olga I. Zrobok,
Tatiana V. Vashurina,
Irina N. Lupan,
Mikhail Yu. Kagan,
Alexey N. Tsygin https://doi.org/10.15690/pf.v16i2.2004
Abstract
The authors provide a review of current clinical guidelines regarding medical care provided to children with Bartter’s syndrome — impaired renal tubular function (loop of Henle) with the development of hypokalemia, hypochloremia, metabolic alkalosis and hyperreninemic hyperaldosteronism. The specifics of disease epidemiology, etiology and pathogenesis are described. The issues of differential diagnosis and treatment based on the principles of evidence are covered.
Supporting agencies: Not specified
About the Authors
Alexander A. Baranov
Central Hospital of the Russian Academy of Sciences
Russian Federation
Moscow.
Russian Federation
Moscow.
Leyla S. Namazova-Baranova
Central Hospital of the Russian Academy of Sciences; N.I. Pirogov Russian National Research Medical University
Russian Federation
Moscow.
Russian Federation
Moscow.
Tatyana V. Sergeeva
National Medical Research Center for Children’s Health
Russian Federation
Moscow.
Russian Federation
Moscow.
Olga V. Chumakova
National Medical Research Center for Children’s Health
Russian Federation
Moscow.
Russian Federation
Moscow.
Svetlana S. Paunova
National Medical Research Center for Children’s Health
Russian Federation
Moscow.
Russian Federation
Moscow.
Nurali Z. Zokirov
Central Children’s Hospital of the Federal Medical and Biological Agency
Russian Federation
Moscow.
Russian Federation
Moscow.
Olga V. Komarova
National Medical Research Center for Children’s Health
Russian Federation
Moscow.
Russian Federation
Moscow.
Tea V. Margieva
Central Hospital of the Russian Academy of Sciences
Russian Federation
Moscow.
Russian Federation
Moscow.
Vladimir K. Tatochenko
National Medical Research Center for Children’s Health
Russian Federation
Moscow.
Russian Federation
Moscow.
Maya D. Bakradze
National Medical Research Center for Children’s Health
Russian Federation
Moscow.
Russian Federation
Moscow.
Elena N. Tsygina
National Medical Research Center for Children’s Health
Russian Federation
Moscow.
Russian Federation
Moscow.
Olga I. Zrobok
National Medical Research Center for Children’s Health
Russian Federation
Moscow.
Russian Federation
Moscow.
Tatiana V. Vashurina
National Medical Research Center for Children’s Health
Russian Federation
Moscow.
Russian Federation
Moscow.
Irina N. Lupan
South Ural State Medical University
Russian Federation
Russian Federation
Chelyabinsk.
Mikhail Yu. Kagan
Regional Children’s Hospital
Russian Federation
Russian Federation
Orenburg.
Alexey N. Tsygin
National Medical Research Center for Children’s Health
Russian Federation
Moscow.
Russian Federation
Moscow.
References
1. Detskaya nefrologiya: prakticheskoe rukovodstvo. Ed by E Lojman, AN Tsygin, AA Sarkisyan. Moscow: Litterra; 2010. 400 p. (In Russ).
2. Fremont OT, Chan JC. Understanding Bartter syndrome and Gitelman syndrome. World J Pediatr. 2012;8(1):25–30. doi: 10.1007/s12519-012-0333-9.
3. Krämer BK, Bergler T, Stoelcker B, Waldegger S. Mechanisms of disease: the kidney-specific chloride channels ClCKA and ClCKB, the Barttin subunit, and their clinical relevance. Nat Clin Pract Nephrol. 2008;4(1):38–46. doi: 10.1038/ncpneph0689.
4. Puricelli E, Bettinelli A, Borsa N, et al. Long-term follow-up of patients with Bartter syndrome type I and II. Nephrol Dial Transplant. 2010;25(9):2976–2981. doi: 10.1093/ndt/gfq119.
Review
For citations:
Baranov A.A., Namazova-Baranova L.S., Sergeeva T.V., Chumakova O.V., Paunova S.S., Zokirov N.Z., Komarova O.V., Margieva T.V., Tatochenko V.K., Bakradze M.D., Tsygina E.N., Zrobok O.I., Vashurina T.V., Lupan I.N., Kagan M.Yu., Tsygin A.N. Loop tubulopathies: Bartter’s syndrome. Pediatric pharmacology. 2019;16(2):85-90. (In Russ.) https://doi.org/10.15690/pf.v16i2.2004
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