XENON ANESTHESIA IN CHILDREN: BIS-MONITORING
https://doi.org/10.15690/pf.v10i6.897
Abstract
We conducted 60 low-flow xenon anesthesias in children of 1-18 years of age. We measured the sedation level using bispectral (BIS) index and clinically on the stage of induction, xenon anesthesia maintenance and during recovery. The trial showed that, according to the clinical and BIS-monitoring data, sevoflurane inhalational induction in children of 1-5 years of age and propofol intravenous induction in children of 6-18 years of age provides children with the required sedation level. BIS index objectively reflects intensity of the sedative component of an anesthesia both in the junior and the senior age groups on the stages of xenon anesthesia maintenance and during recovery.
About the Authors
V. G. Bagaev
Research institute of urgent pediatric surgery and traumatology, Moscow
Russian Federation
MD, leading research scientist at the Department of Anesthesiology and Intensive Care of Research institute of urgent pediatric surgery and traumatology
Russian Federation
MD, leading research scientist at the Department of Anesthesiology and Intensive Care of Research institute of urgent pediatric surgery and traumatology
E. V. Devaykin
Regional Children’s Clinical Hospital № 1, Yekaterinburg, Russian Federation
Russian Federation
Russian Federation
V. G. Amcheslavskiy
Research Institute of Urgent Surgery and Traumatology, Moscow, Russian Federation
Russian Federation
Russian Federation
V. I. Lukyanov
Research Institute of Urgent Surgery and Traumatology, Moscow, Russian Federation
Russian Federation
Russian Federation
M. Y. Davydov
Research Institute of Urgent Surgery and Traumatology, Moscow, Russian Federation
Russian Federation
Russian Federation
M. V. Bykov
Research Institute of Urgent Surgery and Traumatology, Moscow, Russian Federation
Russian Federation
Russian Federation
References
1. Goto T., Suwa K., Uezono S. et al. The blood-gas partition coefficient of xenon may be lower than generally accepted. British Journal of Anaesthesia. 1998; 80: 255–256.
2. Goto T., Saito H., Shinkai M. et al. Xenon provides faster emergence from anesthesia than does nitrous oxide-sevoflurane or nitrous oxide-isoflurane. Anesthesiology. 1997; 86: 1273–1278.
3. Nakata Y., Goto T., Ishiguro Y. et al. Minimum alveolar concentration-awake of Xenon alone and in combination with isoflurane or sevoflurane. Anesthesiology. 2000; 93 (5): 1188–1193.
4. Luttropp H. H., Romner B., Perhag L. et al. Left ventricular performance and cerebral haemodynamics during xenon anaesthesia. A transoesophageal echocardiography and transcranial Doppler sonography study. Anaesthesia. 1993; 48: 1045–1049.
5. Dingley J., King R., Hughes L. et al. Exploration of xenon as a potential cardiostable sedative: a comparison with propofol after cardiac surgery. Anaesthesia. 2001; 56: 829–835.
6. Wilhelm S., Ma D., Maze M. et al. Effects of xenon on in vitro and in vivo models of neuronal injury. Anesthesiology. 2002; 96: 1485–1491.
7. Ma D., Wilhelm S., Maze M. et al. Neuroprotective and neurotoxic properties of the ‘inert’ gas, xenon. British Journal of Anaesthesia. 2002; 89: 739–746.
8. Suslov N. I., Potapov V. N., Shpisman M. N. et al. Primenenie ksenona v meditsine [Xenon in Medicine]. Tomsk, Izd-vo Tomskogo universiteta, 2009. 300 p.
9. Kozlov I. A., Voronin S. V., Stepanova O. V. Ksenonovaya anesteziya u bol'nykh vysokogo riska. V sb.: Ksenon i ksenonsberegayushchie tekhnologii v meditsine-2005 [Xenon Anesthesia in Patients at High Risk. Proc .: Xenon and Xenon-saving Technologies in Medicine-2005]. Moscow, NIKIET, 2005. pp. 68–72.
10. Dinse A., Fohr K. J., Georgieff M. et al. Xenon reduces glutamate-, AMPA, and kainate-induced membrane currents in cortical neurones. British Journal of Anaesthesia. 2005; 94: 479–485.
11. Fahlenkamp A. V., Krebber F., Rex S. et al. Bispectral index monitoring during balanced xenon or sevoflurane anaesthesia in elderly patients. British Journal of Anaesthesia. 2010; 27 (10): 906–911.
12. Likhvantsev V. V., Subbotin V. V., Petrov O. V. et al. Monitoring BIS i INEEG pri anestezii ksenonom. Sb.: Al'manakh anesteziologii i reanimatologii № 1. Materialy 2-i sessii [BIS Monitoring during Anesthesia and INEEG Xenon. Coll.: Almanac Anesthesiology and Intensive Care № 1. Proceedings of the 2nd Session]. 2001. p. 29.
13. Morita M. J., LattaW., Hambro K., Snider M. Accumulation of methane, acetone and nitrogen in the inspired gas during closed circuit anesthesia. Anesth Analg. 1985; 64: 343–347.
14. Fahlenkamp A. V., Krebber F., Rex S. et al. Bispectral index monitoring during balanced xenon or sevoflurane anaesthesia in elderly patients. Eur. J. Anaesthesiol. 2010 Oct; 27 (10): 906–911.
15. Nakata Y., Goto T., Morita S. Comparison of inhalation inductions with xenon and sevoflurane. Acta Anaesthesiol Scand. 1997; 41: 1157–1161.
Review
For citations:
Bagaev V.G., Devaykin E.V., Amcheslavskiy V.G., Lukyanov V.I., Davydov M.Y., Bykov M.V. XENON ANESTHESIA IN CHILDREN: BIS-MONITORING. Pediatric pharmacology. 2013;10(6):61-64. (In Russ.) https://doi.org/10.15690/pf.v10i6.897
Views:
811
Email this article 