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Extrapulmonary Conditions, Concomitant of Bronchopulmonary Dysplasia, in Babies of the First 3 Years of Life: Results of a Retrospective Cross-Sectional Study

https://doi.org/10.15690/pf.v13i5.1637

Abstract

Background: There are few data on co-occurring with bronchopulmonary dysplasia diseases but there is no single point of view on their mutual effect.

Objective: Our aim was to learn the structure and frequency of extrapulmonary disease, concomitant of bronchopulmonary dysplasia, in children aged up to 3 years.

Methods. A retrospective analysis of histories of 93 children with bronchopulmonary dysplasia with an analysis of the consequences of perinatal pathology structure was carried out.

Results. On average, each patient with bronchopulmonary dysplasia accounted for 5 comorbidities. The most common (89; 96%) were perinatal lesions of the nervous system and their consequences. In children with bronchopulmonary dysplasia at the age of 3 years there was a relatively low incidence of hydrocephalus and, on the contrary, high — of infantile cerebral palsy. Violations of the organs of vision were found in 58 (62%) children, malnutrition and other violations of physical development — in 58 (62%) and 27 (29%), respectively, and the cardiovascular system pathology — in 59 (63%).

Conclusion. The most commonly, extrapulmonary pathology, co-occuring with bronchopulmonary dysplasia, includes neurological deficit with psychomotor retardation, violations of organs of vision, pathology of the cardiovascular system, malnutrition/delay in physical development.

About the Authors

K. A. Kazakova
Scientific Center of Children’s Health
Russian Federation


L. S. Namazova-Baranova
Scientific Center of Children’s Health I.M. Sechenov First Moscow State Medical University Pirogov Russian National Research Medical University
Russian Federation


Ju. S. Akoev
Scientific Center of Children’s Health
Russian Federation


I. V. Davydova
Scientific Center of Children’s Health I.M. Sechenov First Moscow State Medical University
Russian Federation


A. V. Migali
Scientific Center of Children’s Health Pirogov Russian National Research Medical University
Russian Federation


V. M. Studenikin
Scientific Center of Children’s Health Pirogov Russian National Research Medical University
Russian Federation


S. P. Lazareva
Scientific Center of Children’s Health
Russian Federation


References

1. Давыдова И.В., Намазова-Баранова Л.С., Яцык Г.В., и др. Профилактические стратегии на этапах формирования и течения бронхолегочной дисплазии // Педиатрическая фармакология. — 2014. — Т. 11. — № 2 — С. 34–40. [Davydova IV, Namazova- Baranova LS, Yatsyk GV, et al. Preventive strategies in the stages of formation and course of bronchopulmonary dysplasia. Pediatric pharmacology. 2014;11(2):34–40. (In Russ).] doi: 10.15690/pf.v11i2.955.

2. Баранов А.А., Намазова-Баранова Л.С., Давыдова И.В. Совре менные подходы к профилактике, диагностике и лечению бронхолегочной дисплазии. — М.: ПедиатрЪ; 2013. — 176 с. [Baranov AA, Namazova-Baranova LS, Davydova IV. Sovremennye podkhody k profilaktike, diagnostike i lecheniyu bronkholegochnoi displazii. Moscow: Pediatr; 2013. 176 p. (In Russ).]

3. Давыдова И.В. Формирование, течение и исходы бронхоле гочной дисплазии у детей: автореф. дис. … док. мед. наук. — М.; 2010. — 48 с. [Davydova IV. Formirovanie, techenie i iskhody bronkholegochnoi displazii u detei. [dissertation abstract] Moscow; 2010. 48 p. (In Russ).]

4. Овсянников Д.Ю., Комлева Н.А., Оболадзе Т.Б., и др. Современные алгоритмы диагностики бронхолегочной дисплазии // Вопросы диагностики в педиатрии. — 2011. — Т. 3. — № 1 — С. 12–20. [Ovsyannikov DYu, Komleva NA, Oboladze TB, et al. Modern algorithms for diagnostics of bronchopulmonary dysplasia. Pediatric diagnostics. 2011;3(1):12–20. (In Russ).]

5. Wu SY, Gupta S, Chung-Ming CM, Yeh TF. Bronchopulmonary dysplasia. In: Irusen E.M., editor. Lung diseases — selected state of the art reviews. Rijeka (Croatia): InTech Publ; 2012. p. 463–484.

6. Федеральные клинические рекомендации по ведению детей с бронхолегочной дисплазией. — М.: СПР/РАСПМ; 2014. — 31 с. [Federal’nye klinicheskie rekomendatsii po vedeniyu detei s bronkholegochnoi displaziei. Moscow: SPR/RASPM; 2014. 31 p. (In Russ).]

7. Wilson TT, Waters L, Patterson CC, et al. Neurodevelopmental and respiratory follow-up results at 7 years for children from the United Kingdom and Ireland enrolled in a randomized trial of early and late postnatal corticosteroid treatment, systemic and inhaled (the Open Study of Early Corticosteroid Treatment). Pediatrics. 2006;117(6):2196–2205. doi: 10.1542/peds.2005-2194.

8. Сергеева О.В. Стратификация риска развития бронхолегочной дисплазии у недоношенных новорожденных // Бюллетень медицинских интернет-конференций. — 2012. — Т. 2. — № 11 — С. 909–911. [Sergeeva OV. Stratifikatsiya riska razvitiya bronkholegochnoi displazii u nedonoshennykh novorozhdennykh. Byulleten’ meditsinskikh internet-konferentsii. 2012;2(11): 909–911. (In Russ).]

9. Мерзлова Н.Б., Курносов Ю.В., Винокуров Л.Н., Батурин В.И. Катамнез детей, рожденных с очень низкой и экстремально низкой массой тела // Фундаментальные исследования. — 2003. — № 3–1 — С. 121–125. [Merzlova NB, Kurnosov YV, Vinokurov LN,

10. Baturin VI. Catamnesis of child which were born with very low baby weight and extremely low baby weight. Fundamental’nye issledovaniya. 2003;(3–1):121–125. (In Russ).]

11. Овсянников Д.Ю., Кузьменко Л.Г., Дегтярева Л.А., Зайцева Э.Г. Течение бронхолегочной дисплазии у детей грудного и раннего возраста // Педиатрия. Журнал им. Г.Н. Сперанского. — 2007. — Т. 86. — № 4 — С. 35–42. [Ovsyannikov DYu, Kuzmenko LG, Degtyareva EA, Zaitseva EG. Bronchopulmonary dysplasia in infants. Pediatriia. 2007;86(4):35–42. (In Russ).]

12. Бойцова Е.В., Богданова А.В., Овсянников Д.Ю. Последствия бронхолегочной дисплазии для респираторного здоровья детей, подростков и молодых взрослых // Вопросы диагностики в педиатрии. — 2013. — Т. 5. — № 1 — С. 5–11. [Boytsova EV, Bogdanova AV, Ovsyannikov DYu. The consequences of bronchopulmonary dysplasia for respiratory health of children, adolescents and young adults. Pediatric diagnostics. 2013;5(1):5–11. (In Russ).]

13. Schmidt B, Roberts RS, Davis PG, et al. Prediction of late death or disability at age 5 years using a count of 3 neonatal morbidities in very low birth weight infants. J Pediatr. 2015;167(5):982–986. doi:10.1016/j.jpeds.2015.07.067.

14. Fenton T, Kim JH. A systematic review and meta-analysis to revise the Fenton growth chart for preterm infants. BMC Pediatr. 2013;13(1):59. doi: 10.1186/1471-2431-13-59.

15. WHO Multicentre Growth Reference Study Group. WHO Child Growth Standarts based on length/height, weight and age. Acta Paediatr. 2006;95(Suppl 450):76–85. doi: 10.1111/j.1651-2227.2006.tb02378.x.

16. Шамансуров Ш.Ш., Студеникин В.М. Неврология раннего детства. — Ташкент: ИПТД; 2010. — 616 с. [Shamansurov ShSh, Studenikin VM. Nevrologiya rannego detstva. Tashkent: IPTD; 2010. 616 p. (In Russ).]

17. Бениова С.Н., Руденко Н.В., Шегеда М.Г., и др. Сравнительный анализ развития детей, рожденных с очень низкой и экстремально низкой массой тела, на первом году жизни в Приморском крае // Современные проблемы науки и образования. — 2013. — № 5 — С. 356. [Beniova SN, Rudenko NV, Shegeda MG, et al. Comparative analysis of the development of infants with very low birth weight and extremely low birth weight performed during the first year of life in Primorsky region. Sovremennye problemy nauki i obrazovaniya. 2013;(5):356. (In Russ).]

18. Ермолина Ю.В., Намазова-Баранова Л.С., Мамедьяров А.М., и др. Роль диффузионной тензорной магнитно-резонансной томографии и трактографии в диагностике структурных повреждений головного мозга у детей с церебральными параличами // Вопросы современной педиатрии. — 2016. — Т. 15. — № 2 — С. 141–147. [Ermolina YV, Namazova-Baranova LS, Mamedyarov AM, et al. The role of diffusion-tensor magnetic resonance imaging and tractography in the diagnosis of structural brain disorders in children with cerebral palsy. Current pediatrics. 2016;15(2):141–147. (In Russ).] doi: 10.15690/vsp.v15i2.1531.

19. Jobe AH. The new bronchopulmonary dysplasia. Curr Opin Pediatr. 2011;23(2):167–172. doi: 10.1097/mop.0b013e3283423e6b.

20. Бабцева А.Ф., Заболотских Т.В., Романцова Е.Б., и др. Наблюдение глубоко недоношенных детей на амбулаторном этапе. Учебное пособие для студентов лечебного и педиатрического факультетов, ординаторов, аспирантов, интернов, педиатров. — Благовещенск; 2011. — 35 с. [Babtseva AF, Zabolotskikh TV, Romantsova EB, et al. Nablyudenie gluboko nedonoshennykh detei na ambulatornom etape. Uchebnoe posobie dlya studentov lechebnogo i pediatricheskogo fakul’tetov, ordinatorov, aspirantov, internov, pediatrov. Blagoveshchensk; 2011. 35 p. (In Russ).]

21. Kajantie E, Strang-Karisson S, Hovi P, et al. Adults born at very low birth weight exercise less than their peers born at term. J Pediatr. 2010;157(4):610–616. doi: 10.1016/j.jpeds.2010.04.002.

22. Hilgendorff A, O’Reilly MA. Bronchopulmonary dysplasia early changes leading to long- term consequences. Front Med (Lausanne). 2015;2:2. doi: 10.3389/fmed.2015.00002.

23. Tokuhiro Y, Yoshida T, Nakabayashi Y, et al. Reduced oxygen protocol decreases the incidence of threshold retinopathy of prematurity in infants of < 33 weeks gestation. Pediatr Int. 2009; 51(6):804–806. doi: 10.1111/j.1442-200x.2009.02856.x.


Review

For citations:


Kazakova K.A., Namazova-Baranova L.S., Akoev J.S., Davydova I.V., Migali A.V., Studenikin V.M., Lazareva S.P. Extrapulmonary Conditions, Concomitant of Bronchopulmonary Dysplasia, in Babies of the First 3 Years of Life: Results of a Retrospective Cross-Sectional Study. Pediatric pharmacology. 2016;13(5):431-435. (In Russ.) https://doi.org/10.15690/pf.v13i5.1637

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