USE OF DIFFUSION-WEIGHTED MAGNETIC RESONANCE IMAGING FOR REVEALING HYPOXIC-ISCHEMIC BRAIN LESIONS IN NEONATES
https://doi.org/10.15690/pf.v11i1.900
Abstract
The article presents advantages of use of diffusion-weighted magnetic resonance imaging (DW MRI) for revealing hypoxic-ischemic brain lesions in neonates. The trial included 97 neonates with perinatal brain lesion who had been undergoing treatment at a resuscitation department or neonatal pathology department in the first month of life. The article shows high information value of diffusion-weighted images (DWI) for diagnostics of hypoxic-ischemic lesions in comparison with regular standard modes. In the event of no structural brain lesions of neonates, pronounced increase in signal characteristics revealed by DWI indicated considerable pathophysiological alterations. Subsequently, children developed structural alterations in the form of cystic encephalomalacia with expansion of cerebrospinal fluid spaces manifested with pronounced neurological deficit. DW MRI has been offered as a method of prognosticating further neurological development of children on early stages.
About the Authors
E. V. Shimchenko
Kuban State Medical University, Moscow
Krasnodar City Clinical Emergency Hospital
Russian Federation
neurologist, extramural postgraduate of the department of pediatrics with a course of neonatology at Kuban State Medical University, head of the pediatric department at Krasnodar city clinical emergency hospital
Russian Federation
neurologist, extramural postgraduate of the department of pediatrics with a course of neonatology at Kuban State Medical University, head of the pediatric department at Krasnodar city clinical emergency hospital
E. I. Kleshchenko
Kuban State Medical University, Krasnodar, Russian Federation
Children’s territorial clinical hospital, Krasnodar, Russian Federation
Russian Federation
Russian Federation
K. F. Goloseyev
Children’s territorial clinical hospital, Krasnodar, Russian Federation
Russian Federation
Russian Federation
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Review
For citations:
Shimchenko E.V., Kleshchenko E.I., Goloseyev K.F. USE OF DIFFUSION-WEIGHTED MAGNETIC RESONANCE IMAGING FOR REVEALING HYPOXIC-ISCHEMIC BRAIN LESIONS IN NEONATES. Pediatric pharmacology. 2014;11(1):69-73. https://doi.org/10.15690/pf.v11i1.900
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