MORPHOLOGICAL CHARACTERISTICS OF ERYTHROCYTES AT UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA IN CHILDREN
https://doi.org/10.15690/pf.v11i1.898
Abstract
Examination of 73 children of 8–12 years of age was conducted in order to study morphological characteristics of erythrocytes at undifferentiated connective tissue dysplasia (UCTD). Scanning electron microscopy revealed significant alterations of surface architectonics of red blood cells, characterized by reduction in the number of discocytes and increase in the number of transformed and degenerative cell forms in the group of children with UCTD without development of anemic syndrome. The most intensive morphological presentation disorders of red blood cells were registered in children with UCTD and anemic syndrome. The article shows that structural inferiority of erythrocyte membranes is a pathogenetic anemia development factor in children with connective tissue dysplasia
About the Authors
D. A. Ponomareva
Siberian State Medical University, Tomsk
Russian Federation
MD, assistant at the department of ambulatory pediatrics with a course of propedeutics of pediatric diseases of the SibSMU
Russian Federation
MD, assistant at the department of ambulatory pediatrics with a course of propedeutics of pediatric diseases of the SibSMU
T. A. Nagayeva
Siberian State Medical University, Tomsk, Russian Federation
Russian Federation
Russian Federation
I. I. Balasheva
Siberian State Medical University, Tomsk, Russian Federation
Russian Federation
Russian Federation
N. M. Shevtsova
Siberian State Medical University, Tomsk, Russian Federation
Russian Federation
Russian Federation
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Review
For citations:
Ponomareva D.A., Nagayeva T.A., Balasheva I.I., Shevtsova N.M. MORPHOLOGICAL CHARACTERISTICS OF ERYTHROCYTES AT UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA IN CHILDREN. Pediatric pharmacology. 2014;11(1):63-65. https://doi.org/10.15690/pf.v11i1.898
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