Reticulocyte Indices in Diagnosis and Control of Effectiveness of Treatment of Iron Deficiency Conditions in Children
https://doi.org/10.15690/pf.v12i6.1494
Abstract
High prevalence of iron-deficiency conditions (IDC) in children dictates the need in searching for sensitive, accurate and simple methods of identifying such diseases on early stages of development. New methods of laboratory screening diagnosis are especially needed. The article presents an analysis of new methods of IDC laboratory diagnosis — hematological and biochemical. It presents a discussion of role of a new parameter — mean reticulocyte hemoglobin content (CHr) — for IDC diagnosis and treatment effectiveness control. The article presents data on CHr sensitivity and specificity as compared with the other hematological parameters frequently used for IDC diagnosis.
About the Authors
I. N. Zakharova
Russian Medical Academy of Postgraduate Education, Moscow, Russian Federation
Russian Federation
Russian Federation
I. S. Tarasova
Dmitriy Rogachev Federal Research and Clinical Center for Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation
Russian Federation
Russian Federation
V. M. Chernov
Dmitriy Rogachev Federal Research and Clinical Center for Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation
Russian Federation
Russian Federation
E. B. Machneva
Russian Medical Academy of Postgraduate Education, Moscow, Russian Federation
Russian Federation
Russian Federation
T. M. Vasilyeva
City Pediatric Hospital No. 133, Moscow, Russian Federation
Russian Federation
Russian Federation
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Review
For citations:
Zakharova I.N., Tarasova I.S., Chernov V.M., Machneva E.B., Vasilyeva T.M. Reticulocyte Indices in Diagnosis and Control of Effectiveness of Treatment of Iron Deficiency Conditions in Children. Pediatric pharmacology. 2015;12(6):692-696. https://doi.org/10.15690/pf.v12i6.1494
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