EFFECT OF ALLERGEN-SPECIFIC IMMUNOTHERAPY COURSES ON COGNITIVE ACTIVITY IN CHILDREN WITH POLLINOSIS
https://doi.org/10.15690/pf.v11i2.950
Abstract
Relevance. Allergic pathology, particularly, pollinosis, may reduce cognitive functions in children. Objective: study effect of allergen-specific immunotherapy on cognitive functions in children with pollinosis and relation of cognitive functions dynamics to repeated ASIT courses. Patients and methods. We determined condition of cognitive functions in 97 children of 8‑17 years of age with pollinosis in comparison with their healthy peers using a psychophysiological computer complex “Psychomath”. Results. We revealed reduction in cognitive activity parameters in most children with pollinosis during remission. Concurrent persisting allergic rhinitis aggravated reducing in cognitive functions parameters. Conclusion. We confirmed positive effect of allergen-specific immunotherapy: cognitive functions improve significantly in children with pollinosis; the effect becomes more pronounced after repeated courses.
About the Authors
O. I. MuradovaRussian Federation
MD, research scientist at the cognitive pediatrics department of the research institute of preventive pediatrics and medical rehabilitation of the SCCH (Federal State Budgetary Institution)
L. S. Namazova-Baranova
Russian Federation
G. A. Karkashadze
Russian Federation
O. I. Maslova
Russian Federation
R. M. Torshkhoeva
Russian Federation
A. Y. Tomilova
Russian Federation
A. A. Alexeeva
Russian Federation
T. V. Turti
Russian Federation
E. A. Vishnyova
Russian Federation
T. A. Konstantinidi
Russian Federation
References
1. Torres-Borrego J., Molina-Teran A. B., Montes-Mendoza C. Prevalence and associated factors of allergic rhinitis and atopic dermatitis in children. Allergol. Immunopathol. 2008; 36(2): 90–100.
2. Il'ina N.I. Seasonal allergic rhinitis. Consilium Medicum = Consilium Medicum. 2002; 2: 4–7.
3. Namazova-Baranova L.S. Allergiya u detei: ot teorii — k praktike [Allergy in Children: from Theory to Practice]. Moscow, Union of Pediatricians of Russia, 2010-2011. pp. 539-667.
4. Karkashadze G.A., Maslova O.I., Namazova-Baranova L.S. Current issues of diagnosis and treatment of mild cognitive impairments in children. Pediatricheskaya farmakologiya = Pediatric pharmacology. 2011; 5(8): 6–12.
5. Gogberashvili T.Yu., Karkashadze G.A., Namazova-Baranova L.S. et al. Neuropsycological methods in pediatrics: possibilities and application opportunities. Pediatricheskaya farmakologiya = Pediatric pharmacology. 2011; 6(8): 83–87.
6. Tomilova A.Yu., Namazova L.S., Kuzenkova L.M. et al. Kognitivnye funktsii i kachestvo zhizni u detei s allergicheskim rinitom (posobie dlya vrachei) [Cognitive Functions and Quality of Life in Children with Allergic Rhinitis (Manual)]. Moscow, Scientific Center of Children’s Health of the Russian Academy of Medical Sciences (State Institution), 2007. pp. 25-55.
7. Namazova L.S. Patogeneticheskie osnovy differentsirovannogo lecheniya bronkhial'noi astmy u detei. Avtoref. dis. …dokt. med. nauk [Pathogenic Principles of Differentiated Treatment of Bronchial Asthma in Children. Author’s abstract]. Moscow, 2000. pp. 21–23.
8. Kozlov V.S., Derzhavina L.L., Kramnoi A.I. Vestnik otorinolaringologii = Bulletin of otolaryngology. 2006; 2: 44–48.
9. Baranov A.A., Maslova O.I., Namazova-Baranova L.S. Vestnik Rossiiskoi akademii meditsinskikh nauk = Annals of RAMS. 2012; 8: 26–33.
10. Muradova O.I., Namazova-Baranova L.S., Torshkhoeva R.M., Karkashadze G.A., Shiryaeva O.A. Pediatricheskaya farmakologiya = Pediatric pharmacology. 2012; 9(2): 89–98.
11. Hellings P. W., Fokkens W. J. Allergic rhinitis and its impact on otorhinolaryngology. Allergy. 2006; 61(6): 656–664.
12. Karpova E.P., Sokolova M.V. Vestnik otorinolaringologii = Bulletin of otolaryngology. 2007; 5: 54–56.
13. Baranov A.A., Khaitov R.M. Allergologiya i immunologiya [Allergology and Immunology]. Moscow, Soyuz pediatrov Rossii, 2010. 246 p.
14. Torshkhoeva R.M., Namazova-Baranova L.S., Muradova O.I., Tomilova A. Yu., Voznesenskaya N. I. Voprosy sovremennoi pediatrii= Current pediatrics. 2014; 13(1): 155.
15. Muradova O. I., Namazova-Baranova L. S., Torshkhoeva R. M., Karkashadze G. A. Voprosy diagnostiki v pediatrii = Pediatric Diagnostics. 2012; 4(2): 48–50.
16. Maslova O.I., Baranov A.A., Namazova-Baranova L.S., Karkashadze G.A., Mamed'yarov A.M., Lazarev M.L., Mura do va O.I., Konstantinidi T.A. Pediatricheskaya farmakologiya = Pediatric pharmacology. 2012; 9(6): 72–78.
17. Maslova O.I., Goryunova A.V., Gur'eva M.B., Balkanskaya S.V., Dneprova L.I., Golovkina I.D. Use of computer-assisted testing systems for diagnosis of cognitive disorders in schoolchildren with attention deficit hyperactivity disorder. Biomedical Engineering. 2005; 39(1): 6–11.
Review
For citations:
Muradova O.I., Namazova-Baranova L.S., Karkashadze G.A., Maslova O.I., Torshkhoeva R.M., Tomilova A.Y., Alexeeva A.A., Turti T.V., Vishnyova E.A., Konstantinidi T.A. EFFECT OF ALLERGEN-SPECIFIC IMMUNOTHERAPY COURSES ON COGNITIVE ACTIVITY IN CHILDREN WITH POLLINOSIS. Pediatric pharmacology. 2014;11(2):6-12. https://doi.org/10.15690/pf.v11i2.950