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NEW APPROACHES TO TREATMENT OF CHRONIC GINGIVITIS IN CHILDREN

Abstract

The article analyzes efficiency of local immunomodulator manufactured by «npo petrovax farm» for children suffering from chronic gingivitis and multiple caries with congenital and inherited somatic diseases. It evaluated the clinical effect of the medication, the biochemical and immunological parameters of saliva composition of patients who underwent the immunomodulatory therapy. Clinical manifestations of gingivitis disappeared, with the remission during 6 months of the observation. The article shows anti inflammatory, anti oxidant, membrane stabilizing action of the medication. It shows the normalization of cariesogenic products of anaerobic lactate and pyruvate glycolysis, increase of secretory iga (Siga) and lysozyme in the saliva.
Key words: children, gingivitis, immunomodulatory therapy.

About the Authors

E.A. Yur'eva
Moscow scientific institute for pediatrics and children's surgery Russian Medical Technologies
Russian Federation


A.S. Ivanova
State scientific center of Russian Federation. Immunology Institute of Federal Medical Biological Agency
Russian Federation


E.E. Yatskevich
Moscow scientific institute for pediatrics and children's surgery Russian Medical Technologies
Russian Federation


G.G. Osokina
Moscow scientific institute for pediatrics and children's surgery Russian Medical Technologies
Russian Federation


Review

For citations:


Yur'eva E., Ivanova A., Yatskevich E., Osokina G. NEW APPROACHES TO TREATMENT OF CHRONIC GINGIVITIS IN CHILDREN. Pediatric pharmacology. 2007;4(5):82-86.

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ISSN 1727-5776 (Print)
ISSN 2500-3089 (Online)