CLINICAL AND GENETIC PARALLELS ALONG CELIAC DISEASE AMONG TOMSK CHILDREN
Abstract
The article is devoted to the analysis of the genetic predisposition to celiac disease. The authors studied the associations of the HLA genes and modifier genes of the immune response (interleukine 1, inter leukine 1 receptor antagonist, inter leukine 4, α-subunits of interleukine 4 receptor, receptor to D vitamin) along with predisposition to the disease, as well as the variants of its run and accompanied autoimmune diseases (autoimmune thyroiditis, insular diabetes type 1).
Key words: celiac disease, genetic predisposition, genetic analysis.
Key words: celiac disease, genetic predisposition, genetic analysis.
About the Authors
E.I. Kondrat’eva
Siberian State Medical University, Tomsk
Russian Federation
Russian Federation
V.P. Puzyrev
Research Institute of Medical Genetics, Tomsk Scientific Center, Siberian Department of the Russian Academy of Medical Sciences, Tomsk
Russian Federation
Russian Federation
L.P. Nazarenko
Research Institute of Medical Genetics, Tomsk Scientific Center, Siberian Department of the Russian Academy of Medical Sciences, Tomsk
Russian Federation
Russian Federation
A.A. Rudko
Research Institute of Medical Genetics, Tomsk Scientific Center, Siberian Department of the Russian Academy of Medical Sciences, Tomsk
Russian Federation
Russian Federation
G.N. Yankina
Siberian State Medical University, Tomsk
Russian Federation
Russian Federation
E.V. Loshkova
Siberian State Medical University, Tomsk
Russian Federation
Russian Federation
Review
For citations:
Kondrat’eva E., Puzyrev V., Nazarenko L., Rudko A., Yankina G., Loshkova E. CLINICAL AND GENETIC PARALLELS ALONG CELIAC DISEASE AMONG TOMSK CHILDREN. Pediatric pharmacology. 2007;4(5):25-31.
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