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Modern Recommendations for Treating Anaphylactic Shock in Children

https://doi.org/10.15690/pf.v12i4.1425

Abstract

Anaphylaxis is an immediate hypersensitivity reaction. It is characterized by the rapid development of life-threatening conditions caused by circulatory and respiratory disorders, in some cases with lesions of the skin and mucous membranes, and is associated with serious complications, including death. A steady increase in the incidence of various forms of anaphylaxis has been noted in recent decades. Experience shows that many specialists tend to make mistakes after facing severe forms of anaphylaxis (and especially the most severe its manifestation — anaphylactic shock),. These mistakes can not only affect the patient’s quality of life, but also in some cases lead to serious and even fatal consequences. The article deals with the epidemiology and pathogenesis, describes the clinical picture of anaphylaxis/anaphylactic shock, and gives an algorithm for the treatment of the disease. The algorithm is based on European Academy of Allergy and Clinical Immunology recommendations published in 2014.

About the Authors

R. F. Tepaev
Scientific Center of Children’s Health, Moscow, Russian Federation I.M. Sechenov first Moscow State Medical University of Russian Health Ministry, Moscow, Russian Federation
Russian Federation


L. R. Selimzyanova
Scientific Center of Children’s Health, Moscow, Russian Federation I.M. Sechenov first Moscow State Medical University of Russian Health Ministry, Moscow, Russian Federation
Russian Federation


L. S. Namazova-Baranova
Scientific Center of Children’s Health, Moscow, Russian Federation I.M. Sechenov first Moscow State Medical University of Russian Health Ministry, Moscow, Russian Federation Pirogov Russian National Research Medical University, Moscow, Russian Federation
Russian Federation


E. A. Vishnyova
Scientific Center of Children’s Health, Moscow, Russian Federation
Russian Federation


References

1. Ross M. P., Ferguson M., Street D., Klontz K., Schroeder T., Luccioli S. Analysis of food-allergic and anaphylactic events in the National Electronic Injury Surveillance System. J Allergy Clin Immunol. 2008; 121: 166–171.

2. Campbell R. L., Hagan J. B., Manivannan V., Decker W. W., Kanthala A. R., Bellolio M. F., Smith V. D., Li J. T. Evaluation of National Institute of Allergy and Infection Disease/Food Allergy & Anaphylaxis Network criteria for the diagnosis of anaphylaxis in emergency department patients. J Allergy Clin Immunol. 2012; 129: 748–752.

3. Klein J. S., Yocum M. W. Under-reporting of anaphylaxis in a community emergency room. J Allergy Clin Immunol. 1995; 95: 637–638.

4. Clark S., Long A. A., Gaeta T. J., Camargo C. A. Multicenter study of emergency department visits for insect sting allergies. J Allergy Clin Immunol. 2005; 116: 643–649.

5. Mehl A., Wahn U., Niggemann B. Anaphylactic reactions in children — a questionnaire-based survey in Germany. Allergy. 2005; 60: 1440–1445.

6. Campbell R. L., Luke A., Weaver A. L. Prescriptions for self-injectable epinephrine and follow-up referral in emergency department patients presenting with anaphylaxis. Ann Allergy Asthma Immunol. 2008; 101: 631–636.

7. Muraro A., Roberts G., Worm M., Bilo M. B., Brockow K., Fernandez-Rivas M., Santos A. F., Zolkipli Z. Q., Bellou A., Beyer K., Bindslev-Jensen C., Cardona V., Clark A. T., Demoly P., Dubois A. E. J., Dunn Galvin A., Eigenmann P., Halken S., Harada L., Lack G., Jutel M., Niggemann B., Ruеff F., Timmermans F., Vlieg-Boerstra B. J., Werfel T., Dhami S., Panesar S., Akdis C. A., Sheikh A. EAACI Food Allergy and Anaphylaxis Guidelines Group. Anaphylaxis: guidelines from the European Academy of Allergy and Clinical Immunology. Allergy. 2014; 69: 1026–1045.

8. Panesar S. S., Javad S., de Silva D., Nwaru B. I., Hickstein L., Mura ro A., Roberts G., Worm M., Bilo M. B., Cardona V., Dubois A. E., Dunn Galvin A., Eigenmann P., Fernandez-Rivas M., Halken S., Lack G., Niggemann B., Santos A. F., Vlieg-Boerstra B. J., Zolkipli Z. Q., Sheikh A. EAACI Food Allergy and Anaphylaxis Group. The epidemiology of anaphylaxis in Europe: a systematic review. Allergy. 2013 Nov; 68 (11): 1353–1361.

9. Bohlke K., Davis R. L., De Stefano F., Marcy S. M., Braun M. M., Thompson R. S. Epidemiology of anaphylaxis among children and adolescents enrolled in a health maintenance organization. J Allergy Clin Immunol. 2004 Mar; 113 (3): 536–42.

10. Decker W. W., Campbell R. L., Manivannan V., Luke A. S., Sauver J. L., Weaver A., Bellolio M. F., Bergstralh E. J., Stead L. G., Li J. T. The etiology and incidence of anaphylaxis in Rochester, Minnesota: a report from the Rochester Epidemiology Project. J Allergy Clin Immunol. 2008 Dec; 122 (6): 1161–5.

11. Turner P. J., Gowland H. M., Ierodiakonou D., Garcez T., Pumphrey R. J. Boyle Increase in anaphylaxis-related hospitalizations but no increase in fatalities: An analysis of United Kingdom national anaphylaxis data, 1992–2012. J Allergy Clin Immunol. 2015 Apr; 135 (4): 956–963.

12. Kleinman M. E., Chameides L., Schexnayder S. M., Samson R. A., Hazinski M. F., Atkins D. L., Berg M. D., de Caen A. R., Fink E. L., Freid E. B., Hickey R. W., Marino B. S., Nadkarni V. M., Proctor L. T., Qureshi F. A., Sartorelli K., Topjian A., van der Jagt E. W., Zaritsky A. L. Part 14: pediatric advanced life support: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2010 Nov 2; 122 (18 Suppl. 3): S876–908. Doi: 10.1161/Circulationaha.110.971101.

13. Аллергия у детей: от теории — к практике. Под ред. Л. С. Намазовой-Барановой Сер. «Современная педиатрия: от теории — к практике». М.: Союз педиатров России. 2011. 668 с.

14. Аллергология и иммунология. Клинические рекомендации для педиатров. Под ред. А. А. Баранова, Р. М. Хаитова. М.: Союз педиатров России. 2011. 256 с.

15. Балаболкин И. И., Булгакова В. А. (ред.) Клиническая аллергология детского возраста с неотложными состояниями: руководство для врачей. М.: Медицинское информационное агентство. 2011. 264 с.

16. Kemp S. F., Lockey R. F. Anaphylaxis: a review of causes and mechanisms. J Allergy Clin Immunol. 2002 Sep; 110 (3): 341–348.

17. Simons F. E. Anaphylaxis. J Allergy Clin Immunol. 2008 Feb; 121 (2 Suppl.): S402–407.

18. de Silva I. L., Mehr S. S., Tey D., Tang M. L. K. Paediatric ana phylaxis: a 5 year retrospective review. Allergy. 2008; 63: 1071–1076.

19. Pumphrey R. S. H. Lessons for management of anaphylaxis from a study of fatal reactions. Clin Exp Allergy. 2000; 30: 1144–1150.

20. Worm M., Edenharter G., Rueff F., Scherer K., Pfohler C., Mahler V., Treudler R., Lang R., Nemat K., Koehli A., Niggemann B., Hompes S. Symptom profile and risk factors of anaphylaxis in Central Europe. Allergy. 2012; 67: 691–698.

21. Simons F. E. R., Ardusso L. R., Bilo M. B., Dimov V., Ebisawa M., El-Gamal Y. M., Ledford D. K., Lockey R. F., Ring J., Sanchez- Borges M., Senna G. E., Sheikh A., Thong B. Y. World Allergy Organization Guidelines for the assessment and management of anaphylaxis. Curr Opin Allergy Clin Immunol. 2012; 12: 389–399.

22. Pumphrey R. S. H. Lessons for management of anaphylaxis from a study of fatal reactions. Clin Exp Allergy. 2000; 30: 1144–1150.

23. Sampson H. A., Munoz-Furlong A., Campbell R. L., Adkinson N. F. Jr., Bock S. A., Branum A. et al. Second symposium on the definition and management of anaphylaxis: summary report — Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network Symposium. J Allergy Clin Immunol. 2006; 117: 391–397.

24. Ellis B. C., Brown S. G. Parenteral antihistamines cause hypotension in anaphylaxis. Emerg Med Australas. 2013; 25: 92–93.


Review

For citations:


Tepaev R.F., Selimzyanova L.R., Namazova-Baranova L.S., Vishnyova E.A. Modern Recommendations for Treating Anaphylactic Shock in Children. Pediatric pharmacology. 2015;12(4):435-440. (In Russ.) https://doi.org/10.15690/pf.v12i4.1425

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