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Hormone-producing Ovarian Tumors in Children. Literature Review

https://doi.org/10.15690/pf.v21i1.2710

Abstract

Hormone-producing ovarian tumors in girls are an actual problem in modern gynecology, which is associated with certain difficulties in managing patients. Firstly, it is worth taking into account the higher anatomical mobility of tumors in girls than in adults, due to the high location of the ovaries, weakness of the ligamentous apparatus and the active lifestyle of the child, which causes a higher incidence of torsion of the volumetric mass in children. Secondly, surgical treatment of hormone-producing ovarian tumors leads to a decrease in ovarian reserve and irreversible consequences in the reproductive health of patients in the future, which is an extremely undesirable complication in childhood. Therefore, methods of fertility preservation should be discussed with girls and their parents. It is also important to note that hormone-producing ovarian tumors have a certain degree of malignancy and a tendency to recur. Thus, the relevance of this topic lies in the complexity of management of pediatric patients with this pathology due to the clinical features of the course and a higher probability of complications. Hormone-producing ovarian masses should also include follicular cysts and corpus luteum cysts, but the above structures are excluded from the discussion in this article.

About the Authors

Elena V. Sibirskaya
N.I. Pirogov Russian National Research Medical University; Center for Adolescent Reproductive Health protection in the Moscow Region; Russian Children’s Teaching Hospital — branch of N.I. Pirogov Russian National Research Medical University; A.I. Evdokimov Moscow State University of Medicine and Dentistry
Russian Federation

MD, PhD, Professor.

117, Leninskiy avenue, Moscow, 119571


Disclosure of interest:

Not declared



Irina V. Karachentsova
N.I. Pirogov Russian National Research Medical University
Russian Federation

MD, PhD.

Moscow


Disclosure of interest:

Not declared



Angelina A. Sysoeva
N.I. Pirogov Russian National Research Medical University
Russian Federation

Student.

Moscow


Disclosure of interest:

Not declared



Mariia Yu. Chernysheva
N.I. Pirogov Russian National Research Medical University
Russian Federation

Student.

Moscow


Disclosure of interest:

Not declared



Kristina A. Osmanova
N.I. Pirogov Russian National Research Medical University
Russian Federation

Student.

Moscow


Disclosure of interest:

Not declared



Evgenia G. Kotikova
N.I. Pirogov Russian National Research Medical University
Russian Federation

Student.

Moscow


Disclosure of interest:

Not declared



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Review

For citations:


Sibirskaya E.V., Karachentsova I.V., Sysoeva A.A., Chernysheva M.Yu., Osmanova K.A., Kotikova E.G. Hormone-producing Ovarian Tumors in Children. Literature Review. Pediatric pharmacology. 2024;21(1):41-49. (In Russ.) https://doi.org/10.15690/pf.v21i1.2710

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