PARENTERAL FEEDING COMPLICATIONS IN PEDIATRICS
https://doi.org/10.15690/pf.v10i3.694
Abstract
The article is dedicated to parenteral feeding – infusion therapy aimed at introducing water, macro- and micronutrients in concordance with body needs. Different parenteral feeding types are described: complete, partial and additional. It shows that balanced parenteral feeding allows providing the child’s body with the sufficient amount of amino acids, carbohydrates, fats and energy required to maintain a baseline energy level and correct a preceding nutritive insufficiency. Protein-energy homeostasis is the basis for vital activity of the body; it determines the inflammatory response activity, immune status adequacy, disease duration and severity and disease prognosis (to a considerable degree). Long-term parenteral feeding is associated with complications of varying severity: from transitory and mild to severe, requiring operative intervention and liver transplantation. The command of modern recommendations allows a practicing doctor to successfully overcome issues associated with long-term parenteral feeding. The article presents modern data on diagnostics, prevention and treatment of parenteral feeding complications.
About the Authors
R. F. Tepaev
Scientific Center of Children’s Health Moscow, Russian Federation
The First Sechenov Moscow State Medical University, Russian Federation
Russian Federation
PhD, head of the resuscitation and intensive therapy department with a resuscitation and intensive therapy group for newborn and premature infants at the FSBI “Scientific Center of Children’s Health”, professor of the pediatrics department with pediatric rheumatology course at Sechenov First Moscow State Medical University
Russian Federation
PhD, head of the resuscitation and intensive therapy department with a resuscitation and intensive therapy group for newborn and premature infants at the FSBI “Scientific Center of Children’s Health”, professor of the pediatrics department with pediatric rheumatology course at Sechenov First Moscow State Medical University
A. N. Kiryanova
Scientific Center of Children’s Health Moscow, Russian Federation
A. S. Belousova
Scientific Center of Children’s Health Moscow, Russian Federation
E. I. Ilyichyova
Scientific Center of Children’s Health Moscow, Russian Federation
A. V. Lazareva
Scientific Center of Children’s Health Moscow, Russian Federation
O. A. Kryzhanovskaya
Scientific Center of Children’s Health Moscow, Russian Federation
References
1. Tepaev R. F., Aleksandrov A. E., Kirgizov I. V., Smirnova T. N., Rybalko A. S. Parenteral feeding in pediatrics and pediatric surgery. Pediatr. farmakol. = Pediatric pharmacology. 2012; 9 (1): 36–44.
2. Koletzko B., Agostoni C., Ball P., Carnielli V., Chaloner C., Clayton J., Colomb V. et al. ESPEN/ESPGHAN Guidelines on paediatric parenteral nutrition. Clin. Nutr. 2006; 25: 177–360.
3. Goldstein B., Giroir B., Randolph A. and the Members of the International Consensus Conference on Pediatric Sepsis. International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics. Pediatr. Crit. Care Med. 2005; 6: 2–8.
4. Berezhanskii B. V., Zhevnerev A. A. Catheter-related blood flow infections. Klin. mikrobiol. antimikrob. khimioter. = Clinical microbiology and antimicrobial chemotherapy. 2006; 8 (2): 130–144.
5. Smith V. C., Hallett J. W. Subclavian vein thrombosis during prolonged catheterization for parenteral nutrition: early management and long-term follow-up. South Med. J. 1983; 76: 603–606.
6. Lumpkin M. M. Safety alert: hazards of precipitation associated with parenteral nutrition. Am. J. Hosp. Pharm. 1994; 51: 1427–1428.
7. Available at: http://www.berlin-chemie.ru/info/texts/1-4-63.htm
8. Norman K., Pichard C., Lochs H., Pirlich M. Prognostic impact of disease — related malnutrition. Clin. Nutr. 2008; 27: 5–15.
9. Elia M. Changing concepts of nutrient requirements in disease: implications for artificial nutritional support. Lancet. 1995; 345: 1279–1284.
10. Dellert S. F., Farrell M. K., Specker B. L., Heubi J. E. Bone mineral content in children with short bowel syndrome after discontinuation of parental nutrition. J. Pediatr. 1998; 132: 516–519.
11. Fouin-Fortunet H., Le Quernec L., Erlinger S., Lerebours E., Colin R. Hepatic alterations during total parenteral nutrition in patients with inflammatory bowel disease: a possible consequence of lithocholate toxicity. Gastroenterology. 1982; 82: 932–937.
12. Moseley R. H. A molecular basis for jaundice in intrahepatic and extrahepatic cholestasis. Hepatology. 1997; 26: 1682–1684.
Review
For citations:
Tepaev R.F., Kiryanova A.N., Belousova A.S., Ilyichyova E.I., Lazareva A.V., Kryzhanovskaya O.A. PARENTERAL FEEDING COMPLICATIONS IN PEDIATRICS. Pediatric pharmacology. 2013;10(3):26-31. https://doi.org/10.15690/pf.v10i3.694
Views:
1697
Email this article 