VIRAL INFECTIONS IN CHILDREN SUFFERED FROM CISTIC FIBROSIS
Abstract
Results of study of antiviral immunity indicators in patients with mucoviscidosis were presented. A significant antibody deficiency against a number of antigenically unrelated viruses — acute respiratory pathogens and Мycoplasma pneumonia, significantly lower levels of specific cellular antiviral immunity, massive prolonged viremia was identified. Viruses that cause exacerbation of bronchopulmonary process in patients with mucoviscidosis often continue to be detected in blood and in remission. In patients with mucoviscidosis a perverted immune response to viral infection has been revealed.
Key words: mucoviscidosis, antiviral immunity, viremia.
Key words: mucoviscidosis, antiviral immunity, viremia.
About the Authors
N.N. Nisevich
Scientific Center of Children’s Health, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
E.V. Sereda
Scientific Center of Children’s Health, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
N.S. Selyutina
Bureau of the Forensic Department of Health in Moscow
Russian Federation
Russian Federation
O.V. Kriger
Bureau of the Forensic Department of Health in Moscow
Russian Federation
Russian Federation
I.N. Nikishtsev
Bureau of the Forensic Department of Health in Moscow
Russian Federation
Russian Federation
N.L. Agoshkova
Bureau of the Forensic Department of Health in Moscow
Russian Federation
Russian Federation
Review
For citations:
Nisevich N., Sereda E., Selyutina N., Kriger O., Nikishtsev I., Agoshkova N. VIRAL INFECTIONS IN CHILDREN SUFFERED FROM CISTIC FIBROSIS. Pediatric pharmacology. 2011;8(2):43-49.
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