DYNAMICS OF MATRIX METALLOPROTEINASE CONCENTRATION DURING THE TREATMENT OF CHILDREN WITH DILATED CARDIOMYOPATHY’S EARLY DEBUT
Abstract
The article shows the effectiveness of the complex treatment (angiotensin converting enzymes inhibitors, blockers, diuretics and cardiac glycosides) in children with dilated cardiomyopathy with an early debut. The dynamic observation of changes in morphological and functional cardiac parameters was carried out and we studied the content of matrix metalloproteinases in 41 patients on the background of the therapy. The statistically significant positive effect of the combined therapy on the studied parameters after 1–1,5 years of the continuous treatment has been demonstrated.
Key words: dilated cardiomyopathy, matrix metalloproteinases, treatment, children.
Key words: dilated cardiomyopathy, matrix metalloproteinases, treatment, children.
About the Authors
A.S. Gasanov
Azerbaijan Medical University, Baku
Azerbaijan
Azerbaijan
E.N. Basargina
Scientific Center of Children’s Health, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
T.V. Bershova
Scientific Center of Children’s Health, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
Review
For citations:
Gasanov A., Basargina E., Bershova T. DYNAMICS OF MATRIX METALLOPROTEINASE CONCENTRATION DURING THE TREATMENT OF CHILDREN WITH DILATED CARDIOMYOPATHY’S EARLY DEBUT. Pediatric pharmacology. 2011;8(2):40-42.
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