ppharmПедиатрическая фармакологияPediatric pharmacology1727-57762500-3089Издательство «ПедиатрЪ»10.15690/pf.v11i5.1164ppharm-51Research ArticleЛЕКЦИЯLECTUREПИЩЕВАЯ АЛЛЕРГИЯ. РЕКОМЕНДАЦИИ ПО ВВЕДЕНИЮ ПРИКОРМА ПАЦИЕНТАМ С ПИЩЕВОЙ АЛЛЕРГИЕЙ И ДЕТЯМ ИЗ ГРУППЫ РИСКА: ЧТО И КОГДА?Food allergies. Recommendations on supplementary feeding introduction in patients with food allergies and risk group children: what and when?МакароваС. Г.MakarovaS.G.vishneva@nczd.ruВишнёваЕ. А.VishnevaE.A.

кандидат медицинских наук, заведующая отделом стандартизации и клинической фармакологии ФГБНУ «НЦЗД», врач аллерголог-иммунолог отделения восстановительного лечения детей с аллергическими болезнями и заболеваниями органов дыхания НИИ профилактической педиатрии и восстановительного лечения ФГБНУ «НЦЗД» Адрес: 119991, Ломоносовский проспект, д. 2, стр. 1, тел.: +7 (499) 134-03-92

vishneva@nczd.ruНамазова-БарановаЛ. С.Namazova-BaranovaL.S.namazova@nczd.ruАлексееваА. А.AlekseevaA.A.vishneva@nczd.ruТуртиТ. В.TurtiT.V.vishneva@nczd.ruСновскаяМ. А.SnovskayaM.A.

CONFLICT OF INTEREST

The authors have indicated they have no financial relationships relevant to this article to disclose.

vishneva@nczd.ruНаучный центр здоровья детей, Москва, Российская Федерация Первый Московский государственный медицинский университет им. И.М. Сеченова, Российская ФедерацияРоссияScientific Center of Children’s Health, Moscow, Russian Federation Sechenov First Moscow State Medical University, Russian FederationRussian FederationНаучный центр здоровья детей, Москва, Российская Федерация Первый Московский государственный медицинский университет им. И.М. Сеченова, Российская Федерация Российский национальный исследовательский медицинский университет им. Н.И. Пирогова, Москва, Российская ФедерацияРоссияScientific Center of Children’s Health, Moscow, Russian Federation Sechenov First Moscow State Medical University, Russian Federation Pirogov Russian National Medical Research University, Moscow, Russian FederationRussian FederationНаучный центр здоровья детей, Москва, Российская Федерация Российский национальный исследовательский медицинский университет им. Н.И. Пирогова, Москва, Российская ФедерацияРоссияScientific Center of Children’s Health, Moscow, Russian Federation Pirogov Russian National Medical Research University, Moscow, Russian FederationRussian FederationНаучный центр здоровья детей, Москва, Российская ФедерацияРоссияScientific Center of Children’s Health, Moscow, Russian FederationRussian Federation201401102014115Педиатрическая фармакология4551Copyright © Макарова С.Г., Вишнёва Е.А., Намазова-Баранова Л.С., Алексеева А.А., Турти Т.В., Сновская М.А., 20142014Макарова С.Г., Вишнёва Е.А., Намазова-Баранова Л.С., Алексеева А.А., Турти Т.В., Сновская М.А.Makarova S., Vishneva E., Namazova-Baranova L., Alekseeva A., Turti T., Snovskaya M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.pedpharma.ru/jour/article/view/51

Статья посвящена пищевой аллергии. На сегодняшний день в условиях роста распространенности и отсутствия четких прогностических критериев заболевания точная оценка социально-экономического бремени этой проблемы и его влияния на бюджет здравоохранения пока отсутствует. Авторами представлена основанная на патогенетических механизмах развития современная классификация преимущественных клинических проявлений. Рассматриваются терапевтические подходы и предложены рекомендации по расширению рациона как пациентам с проявлениями пищевой аллергии, так и детям из группы риска. Дано понятие перекрестной сенсибилизации, освещена проблема возникновения неиммунных реакций при приеме пищевых продуктов.

Ключевые слова: пищевая аллергия, толерантность, пищевые аллергены, белок коровьего молока, лечебные смеси, паналлергены, перекрестная сенсибилизация, дети из группы риска, элиминационная диета, прикорм, рацион, окно толерантности.

The article is dedicated to food allergies. There still is no accurate estimate of the socioeconomic burden of food allergies and its impact upon the healthcare budget despite increasing prevalence thereof and lack of clear prognostic criteria. The authors present a modern classification of predominant clinical manifestations based on pathogenetic mechanisms of development. They describe therapeutic approaches, propose recommendations on diet broadening for both patients with food allergy manifestations and risk group children, define cross-sensitization and discuss a problem of non-immune reactions to foods.

Keywords: food allergy, tolerance, food allergens, cow milk protein, therapeutic formulae, panallergens, cross-sensitization, risk group children, elimination diet, supplementary feeding, diet, tolerance window.

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The authors declare that there are no conflicts of interest present.