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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ppharm</journal-id><journal-title-group><journal-title xml:lang="ru">Педиатрическая фармакология</journal-title><trans-title-group xml:lang="en"><trans-title>Pediatric pharmacology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-5776</issn><issn pub-type="epub">2500-3089</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/pf.v12i4.1419</article-id><article-id custom-type="elpub" pub-id-type="custom">ppharm-507</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ФАРМАКОЭКОНОМИКА В ПЕДИАТРИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PHARMACOECONOMICS IN PEDIATRICS</subject></subj-group></article-categories><title-group><article-title>Особенности применения и экономическая эффективность полуэлементных смесей для энтерального питания детей в критических состояниях</article-title><trans-title-group xml:lang="en"><trans-title>Half-elemental Nutrition Mixtures for Enteral Nutrition of Children in Critical Conditions: Features of Usage and Economic Efficiency</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Берестенникова</surname><given-names>Л. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Berestennikova</surname><given-names>L. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>научный советник Департамента клинического питания Nestle Health Science Адрес: 115054, Москва, Павелецкая площадь, д. 2, стр. 1, тел.: +7 (961) 996-77-34</p></bio><email xlink:type="simple">berestennikovaln@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Департамент клинического питания Nestle Health Science, Москва, Российская Федерация</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Nestle Health Science Clinical Nutrition Department, Moscow, Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>02</day><month>11</month><year>2015</year></pub-date><volume>12</volume><issue>4</issue><fpage>392</fpage><lpage>397</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Берестенникова Л.Н., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Берестенникова Л.Н.</copyright-holder><copyright-holder xml:lang="en">Berestennikova L.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pedpharma.ru/jour/article/view/507">https://www.pedpharma.ru/jour/article/view/507</self-uri><abstract><p>Энтеральное (зондовое) питание в сравнении с парентеральным показало свое превосходство у пациентов с сохраненной функцией желудочно-кишечного тракта, находящихся в реанимации или отделении интенсивной терапии, которые не могут или не должны по медицинским показаниям принимать пищу. Больным в критическом состоянии, нуждающимся в нутритивной поддержке, международные руководства рекомендуют энтеральный путь введения смесей, при этом оптимальным периодом начала нутритивной поддержки указывают первые сутки. Известно, что и расходы на энтеральное питание значительно ниже таковых у больных из отделений интенсивной терапии, находящихся на внутрисосудистом обеспечении. Использование специализированных продуктов диетического питания — полуэлементных смесей с высокой энергетической плотностью — наиболее физиологично для детей от 1 года и взрослых в критических состояниях, пребывающих в отделениях реанимации и интенсивной терапии.</p></abstract><trans-abstract xml:lang="en"><p>Enteral (tube) nutrition has demonstrated its superiority in comparison with parenteral nutrition for patients with a preserved function of gastrointestinal tract who are in intensive care units, or ICU, and who cannot eat or are not allowed to eat by medical indications. International guidelines recommend enteral injections of mixtures for patients in critical conditions in need of nutritial support. The first twenty-four hour is considered the optimal period for starting nutritional support. It is known that costs of the enteral nutrition are much lower than costs of intravascular supply for patients who are in the ICU. The usage of special-purpose dietary products — half-elemental mixtures with high energy density — is the most physiological for children in ICU from 1 year and for adults in critical conditions.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>острая кишечная недостаточность</kwd><kwd>мальабсорбция</kwd><kwd>раннее энтеральное питание</kwd><kwd>отделение интенсивной терапии.</kwd></kwd-group><kwd-group xml:lang="en"><kwd>acute intestinal failure</kwd><kwd>malabsorption</kwd><kwd>early enteral nutrition</kwd><kwd>intensive care unit</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Marik P. E., Zaloga G. P. Meta-analysis of parenteral nutrition versus enteral nutrition in patients with acute pancreatitis. BMJ. 2004; 328: 1407.</mixed-citation><mixed-citation xml:lang="en">Marik P. E., Zaloga G. P. 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