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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ppharm</journal-id><journal-title-group><journal-title xml:lang="ru">Педиатрическая фармакология</journal-title><trans-title-group xml:lang="en"><trans-title>Pediatric pharmacology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-5776</issn><issn pub-type="epub">2500-3089</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/pf.v11i6.1222</article-id><article-id custom-type="elpub" pub-id-type="custom">ppharm-42</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НЕОТЛОЖНЫЕ СОСТОЯНИЯ У ДЕТЕЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EMERGENCY CONDITIONS IN CHILDREN</subject></subj-group></article-categories><title-group><article-title>СИНДРОМ БОЛИ У ДЕТЕЙ: ДИАГНОСТИКА И ЛЕЧЕНИЕ</article-title><trans-title-group xml:lang="en"><trans-title>PAIN SYNDROME IN CHILDREN: DIAGNOSTICS AND TREATMENT (WITH COMMENTARY BY R.F. TEPAEV)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тепаев</surname><given-names>Р. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Tepaev</surname><given-names>R. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, заведующий отделением реанимации и интенсивной терапии ФГБНУ «Научный центр здоровья детей», профессор кафедры педиатрии с курсом детской ревматологии Первого Московского государственного медицинского университета им. И.М. Сеченова Адрес: 119991, Москва, Ломоносовский проспект, д. 2, стр. 1, тел.: +7 (499) 783-27-91</p></bio><email xlink:type="simple">tepaev@nczd.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Обедин</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Obedin</surname><given-names>A. N.</given-names></name></name-alternatives><email xlink:type="simple">tepaev@nczd.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Научный центр здоровья детей, Москва, Российская Федерация&#13;
Первый Московский государственный медицинский университет им. И.М. Сеченова, Российская Федерация<country>Россия</country></aff><aff xml:lang="en">Scientific Center of Children's Health, Moscow, Russian Federation&#13;
Sechenov First Moscow State Medical University, Moscow, Russian Federation<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Ставропольский государственный медицинский университет, Российская Федерация<country>Россия</country></aff><aff xml:lang="en">Stavropol State Medical University, Stavropol, Russian Federation<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>19</day><month>11</month><year>2014</year></pub-date><volume>11</volume><issue>6</issue><issue-title>Педиатрическая фармакология</issue-title><fpage>86</fpage><lpage>91</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тепаев Р.Ф., Обедин А.Н., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Тепаев Р.Ф., Обедин А.Н.</copyright-holder><copyright-holder xml:lang="en">Tepaev R.F., Obedin A.N.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pedpharma.ru/jour/article/view/42">https://www.pedpharma.ru/jour/article/view/42</self-uri><abstract><p>Боль ― один из самых распространенных симптомов, который ассоциируется с широким кругом заболеваний. Умение правильно оценить и купировать боль является одним из ключевых навыков детского врача. В работе представлены современные данные по физиологии боли, изложена гуморальная теория развития болевого синдрома, клинические проявления нейропатической и ноцицептивной боли. Рассматриваются основные положения по диагностике и измерению боли как одного из основополагающих принципов ведения болевого синдрома. 1 марта 2012 г. Всемирная организация здравоохранения опубликовала новое руководство по лечению персистирующего болевого синдрома у детей. В работе освещены рекомендации по переходу от трехступенчатой к двуступенчатой «обезболивающей лестнице», предусматривающей использование ненаркотических, наркотических, адъювантных анальгетиков и их комбинации. </p><p> </p></abstract><trans-abstract xml:lang="en"><p>Pain is one of the most common symptoms associated with a wide range of diseases. Ability to assess correctly and terminate pain is one of the key skills of a pediatrician. The article presents the modern data on pain physiology, humoral theory of pain syndrome development and clinical manifestations of neuropathic and nociceptive pain. The article presents the main issues of diagnosis and measurement of pain as one of the fundamental principles of pain syndrome management. On March 1, 2012, the World Health Organization published the new guidelines on the treatment of persistent pain syndrome in children. The article also provides recommendations on transition from the three-step “anesthetizing ladder” to the two-step one, which consists in the use of nonnarcotic, narcotic, adjuvant analgesics and combinations thereof.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>боль</kwd><kwd>дети</kwd><kwd>ноцицептивная боль</kwd><kwd>нейропатическая боль</kwd><kwd>наркотические анальгетики</kwd><kwd>ненаркотические анальгетики</kwd><kwd>адъювантные анальгетики</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pain</kwd><kwd>children</kwd><kwd>nociceptive pain</kwd><kwd>neuropathic pain</kwd><kwd>narcotic analgesics</kwd><kwd>nonnarcotic analgesics</kwd><kwd>adjuvant analgesics</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Оценка и ведение болевого синдрома у детей. 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