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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ppharm</journal-id><journal-title-group><journal-title xml:lang="ru">Педиатрическая фармакология</journal-title><trans-title-group xml:lang="en"><trans-title>Pediatric pharmacology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-5776</issn><issn pub-type="epub">2500-3089</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/pf.v23i4.3070</article-id><article-id custom-type="elpub" pub-id-type="custom">ppharm-2877</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>В ПРАКТИКУ ПЕДИАТРА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>For Pediatricians' Practice</subject></subj-group></article-categories><title-group><article-title>Тактика регидратационной терапии детей с острой кишечной инфекцией: внедрение федеральных клинических рекомендаций в практику педиатра</article-title><trans-title-group xml:lang="en"><trans-title>Tactics of Rehydration Therapy in Children with Acute intestinal infection: implementation of Federal guidelines in Pediatric Practice</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8698-3241</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мальцева</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Maltseva</surname><given-names>Yuliya V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мальцева Юлия Вадимовна - к.м.н. наук, доцент кафедры внутренних болезней.</p><p>302026, Орел, ул. Комсомольская, д. 95, тел.: +7 (915) 502-20-98</p></bio><bio xml:lang="en"><p>MD, PhD.</p><p>95, Komsomolskaya Str., Orel, 302026, +7 (915) 502-20-98</p></bio><email xlink:type="simple">79155022098@ya.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1438-5103</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузнецова</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuznetsova</surname><given-names>Tatyana A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кузнецова Татьяна Анатольевна д.м.н.</p><p>Орел</p></bio><bio xml:lang="en"><p>MD, PhD.</p></bio><email xlink:type="simple">vradi@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Орловский государственный университет им. И.С. Тургенева</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Orel State University named after I.S. Turgenev</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>09</day><month>10</month><year>2026</year></pub-date><volume>23</volume><issue>4</issue><fpage>506</fpage><lpage>513</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мальцева Ю.В., Кузнецова Т.А., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Мальцева Ю.В., Кузнецова Т.А.</copyright-holder><copyright-holder xml:lang="en">Maltseva Y.V., Kuznetsova T.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pedpharma.ru/jour/article/view/2877">https://www.pedpharma.ru/jour/article/view/2877</self-uri><abstract><p>Ведущим методом коррекции водно-электролитного баланса у детей с эксикозом I и II степени является оральная регидратационная терапия (ОРТ). В этой связи целью исследования стала минимизация объема инфузионной терапии (ИТ) у детей с острыми кишечными инфекциями (ОКИ) в стационарных условиях.</p><sec><title>Материалы и методы</title><p>Материалы и методы. В исследование включены 899 детей с ОКИ. Основную группу (ОГ, n = 442) составили пациенты, курируемые авторами; в группу сравнения (ГС, n = 457) вошли дети, наблюдавшиеся другими врачами того же отделения. В обеих группах при эксикозе I–II степени проводилась оральная регидратация глюкозо-солевыми растворами: в ОГ — низкоосмолярным (245 мОсм/л), в ГС — гиперосмолярным (282 мОсм/л). При неэффективности ОРТ детям назначали ИТ: в ОГ — изотонический раствор стерофундина, при его отсутствии — раствор Рингер лактат или 0,9% раствор натрия хлорида; в ГС ИТ — глюкозо-солевые растворы (стерофундин Г-5, нормофундин Г-5).</p></sec><sec><title>Результаты</title><p>Результаты. Каждый третий случай ОКИ в обеих группах приходился на инвазивные кишечные инфекции: 31,0% (137/442) в ОГ и 31,9% (146/457) в ГС. В обеих группах преобладали пациенты с эксикозом I–II степени. У детей с эксикозом I степени в ОГ удалось полностью избежать назначения ИТ (100% случаев), при эксикозе II степени — в 20% случаев. В ГС каждый второй пациент с эксикозом I степени получал ИТ, с эксикозом II степени — каждый пятый. Длительность купирования эксикоза и тяжесть состояния, оцениваемые по числу дней, в группах существенно не различались.</p></sec><sec><title>Заключение</title><p>Заключение. Формирование приверженности матерей к проведению ОРТ позволило снизить частоту применения ИТ у детей с ОКИ в 3 раза.</p></sec></abstract><trans-abstract xml:lang="en"><p>The leading method for correcting water and electrolyte imbalance in children with grade I–II dehydration is oral rehydration therapy (ORT).</p><p>The aim of the study was to minimize the volume of infusion therapy (IT) in children with acute intestinal infections (AII) in hospital settings.</p><sec><title>Materials and Methods</title><p>Materials and Methods. The study included 899 children with AII. The main group (MG, n = 442) consisted of patients managed by the authors; the comparison group (CG, n = 457) included children observed by other physicians of the same department. In both groups, oral rehydration with glucose-saline solutions was performed for grade I–II dehydration: in the MG — with a hypo-osmolar solution (245 mOsm/L), in the CG — with a hyperosmolar solution (282 mOsm/L). When ORT was ineffective, IT was prescribed: in the MG — isotonic Sterofundin solution, or Ringer lactate or 0.9% sodium chloride solution if Sterofundin was unavailable; in the CG — glucose-saline solutions (Sterofundin G-5, Normofundin G-5).</p></sec><sec><title>Results</title><p>Results. Every third case of AII in both groups was attributable to invasive intestinal infections: 31.0% (137/442) in the MG and 31.9% (146/457) in the CG. Patients with grade I–II dehydration predominated in both groups. In children with grade I dehydration in the MG, IT was completely avoided (100% of cases); in grade II dehydration, IT was avoided in 20% of cases. In the CG, every second patient with grade I dehydration received IT, and every fifth patient with grade II dehydration received IT. The duration of dehydration resolution and the severity of the condition, assessed by the number of days, did not differ significantly between the groups.</p></sec><sec><title>Conclusion</title><p>Conclusion. Fostering maternal adherence to ORT made it possible to reduce the frequency of IT use in children with AII by 3 times.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>острая кишечная инфекция</kwd><kwd>дети</kwd><kwd>оральная регидратация</kwd><kwd>инфузионная терапия</kwd><kwd>педиатрия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>acute intestinal infection</kwd><kwd>children</kwd><kwd>oral rehydration</kwd><kwd>infusion therapy</kwd><kwd>pediatrics</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Отсутствует</funding-statement><funding-statement xml:lang="en">Not specified</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ротавирусный гастроэнтерит у детей: клинические рекомендации / Евро-Азиатское общество по инфекционным болезням; Ассоциация врачей-инфекционистов Санкт-Петербурга и Ленинградской области. — Минздрав России; 2023. — 45 с.</mixed-citation><mixed-citation xml:lang="en">Rotavirusnyi gastroenterit u detei: Clinical guidelines. 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