ppharmПедиатрическая фармакологияPediatric pharmacology1727-57762500-3089Издательство «ПедиатрЪ»10.15690/pf.v22i4.2941ppharm-2677Research ArticleКЛИНИЧЕСКИЕ РЕКОМЕНДАЦИИCLINICAL RECOMMENDATIONS«Целиакия-2025»: проект клинических рекомендаций по диагностике и лечению целиакии у детей“Celiac Disease-2025”: Project of Clinical Guidelines for the Diagnosis and Treatment of Celiac Disease in Childrenhttps://orcid.org/0009-0008-7422-7925АверкинаН. А.AverkinaNataliya A.

Москва

 Moscow 

https://orcid.org/0000-0003-3987-8112БарановА. А.BaranovAleksander A.

Москва

Moscow

https://orcid.org/0000-0002-1228-443XБельмерС. В.Bel’merSergey V.

Москва

Moscow

https://orcid.org/0009-0007-9973-2293БораеваТ. Т.BoraevaTatiyana T.

Владикавказ

Vladikavkaz

https://orcid.org/0000-0002-0603-3394БоровикТ. Э.BorovikTatiyana A.

Москва

Moscow

https://orcid.org/0000-0001-9893-9291БушуеваТ. В.BushuevaTatiyana V.

Москва

Moscow

https://orcid.org/0000-0001-7398-0562ВишнёваЕ. А.VishnevaElena A.

Москва

Moscow

https://orcid.org/0000-0001-9257-0171ГореловА. В.GorelovAleksander V.

Москва

Moscow

https://orcid.org/0000-0001-6381-0367ГундобинаО. С.GundobinaOlga S.

Москва

Moscow

https://orcid.org/0000-0002-2666-4759ГуроваМ. М.GurovaMargarita M.

Санкт-Петербург; Белгород

Saint Petersburg; Belgorod

https://orcid.org/0000-0003-0668-7336ДмитриеваЮ. А.DmitrievaYuliya A.

Москва

Moscow

https://orcid.org/0000-0003-4200-4598ЗахароваИ. Н.ZakharovaIrina N.

Москва

Moscow

https://orcid.org/0000-0002-0709-1115ЗвонковаН. Г.ZvonkovaNataliya G.

Москва; Владикавказ

Moscow; Vladikavkaz

https://orcid.org/0000-0002-3896-3297ЗвягинА. А.ZvyaginAleksander A.

Воронеж

Voronezh

https://orcid.org/0000-0002-1928-749XЗокировН. З.ZokirovNurali Z.

Москва

Moscow

https://orcid.org/0000-0002-8936-3590КайтуковаЕ. В.KaytukovaElena V.

Москва

Moscow

https://orcid.org/0000-0001-7248-1614КлимовЛ. Я.KlimovLeonid Ya.

Ставрополь

Stavropol

https://orcid.org/0000-0001-6000-5418КомароваЕ. В.KomarovaElena V.

Москва

Moscow

https://orcid.org/0000-0003-2743-1460КорниенкоЕ. А.KornienkoElena A.

Санкт-Петербург

Saint Petersburg

https://orcid.org/0000-0001-6137-6528КондратьеваЕ. И.KondratievaElena I.

Москва

Moscow; Khimki 

https://orcid.org/0000-0002-0731-7153КурьяниноваВ. А.KuryaninovaViktoria A.

Ставрополь

Stavropol

https://orcid.org/0000-0002-3133-8018КуцевС. И.KutsevSergey I.

Москва

Moscow

https://orcid.org/0000-0002-8305-7592ЛохматовМ. М.LokhmatovMaxim M.

Москва

Moscow

https://orcid.org/0000-0002-3043-8674ЛошковаЕ. В.LoshkovaElena V.

Москва; Томск

Moscow; Tomsk

https://orcid.org/0000-0002-4733-3262НалетовА. В.NalyotovAndrew V.

Донецк

Donetsk

https://orcid.org/0000-0002-2209-7531Намазова-БарановаЛ. С.Namazova-BaranovaLeyla S.

Москва

Moscow

https://orcid.org/0000-0002-0992-1709НовиковаВ. П.NovikovaValeriya P.

Санкт-Петербург

Saint Petersburg

https://orcid.org/0000-0001-5214-8072ОдинаеваН. Д.OdinaevaNiso D.

Москва

Khimki

https://orcid.org/0000-0002-6164-0074ПлатоноваМ. М.PlatonovaMariya M.

Москва

Moscow

https://orcid.org/0000-0003-4905-2373ПотаповА. С.PotapovAleksander S.

Москва

Moscow

https://orcid.org/0000-0002-3537-7372РевноваМ. О.RevnovaMariya O.

Санкт-Петербург

Saint Petersburg

https://orcid.org/0000-0001-6395-0407РомановскаяИ. Э.RomanovskayaIrena E.

Санкт-Петербург

Saint Petersburg

https://orcid.org/0000-0002-3993-1246РославцеваЕ. А.RoslavtsevaElena A.

Владикавказ

Vladikavkaz

https://orcid.org/0000-0002-3678-7939СелимзяноваЛ. Р.SelimzyanovaLiliya R.

Москва

Moscow

https://orcid.org/0000-0002-6140-504XСичинаваИ. В.SichinavaIrina V.

Москва

Moscow

https://orcid.org/0000-0002-6521-0936СкворцоваВ. А.SkvortsovaVera A.

Москва

Moscow

https://orcid.org/0000-0002-3697-4283СурковА. Н.SurkovAndrey N.

Москва

Moscow

https://orcid.org/0000-0001-6667-9472ТепаевР. Ф.TepaevRustem F.

Москва

Moscow

https://orcid.org/0000-0001-8586-7946ФисенкоА. П.FisenkoAndrey P.

Москва

Moscow

https://orcid.org/0000-0001-7308-7280ХавкинА. И.KhavkinAnatoly I.

Хавкин Анатолий Ильич, доктор медицинских наук, профессор, руководитель Московского областного центра гастроэнтерологии и гепатологии им. А.В. Мазурина, главный научный сотрудник; профессор кафедры педиатрии Медицинского института; председатель Российского общества детских гастроэнтерологов, гепатологов и нутрициологов, полный член ESPGHAN

 115093, Москва, ул. Большая Серпуховская, д. 62, тел.: +7 (903) 796-59-07 

Khimki; Belgorod

khavkin@nikid.ruhttps://orcid.org/0000-0003-3364-610XЯблоковаЕ. А.YablokovaEkaterina A.

Москва

Moscow; Khimki

https://orcid.org/0000-0001-5792-2012ЯнкинаГ. Н.YankinaGalina N.

Томск

Tomsk

ЭфендиеваК. Е.EfendievaKamilla E.

Москва

Moscow

Центральный научно-исследовательский институт организации и информатизации здравоохраненияРоссияRussian Research Institute of HealthRussian FederationНИИ педиатрии и охраны здоровья детей НКЦ №2 ФГБНУ «РНЦХ им. акад. Б.В. Петровского» ; Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет)РоссияPediatrics and Child Health Research Institute in Petrovsky National Research Centre of Surgery ; I.M. Sechenov First Moscow State Medical University (Sechenov University)Russian FederationРоссийский национальный исследовательский медицинский университет им. Н.И. Пирогова (Пироговский Университет)РоссияPirogov Russian National Research Medical UniversityRussian FederationСеверо-Осетинская государственная медицинская академияРоссияNorth Ossetian State Medical AcademyRussian FederationПервый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет) ; Национальный медицинский исследовательский центр здоровья детейРоссияI.M. Sechenov First Moscow State Medical University (Sechenov University) ; National Medical Research Center of Children’s HealthRussian FederationНациональный медицинский исследовательский центр здоровья детей ; Медико-генетический научный центр им. акад. Н.П. БочковаРоссияNational Medical Research Center of Children’s Health ; Research Centre of Medical GeneticsRussian FederationНИИ педиатрии и охраны здоровья детей НКЦ №2 ФГБНУ «РНЦХ им. акад. Б.В. Петровского» ; Российский национальный исследовательский медицинский университет им. Н.И. Пирогова (Пироговский Университет)РоссияPediatrics and Child Health Research Institute in Petrovsky National Research Centre of Surgery ; Pirogov Russian National Research Medical UniversityRussian FederationПервый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет) ; Центральный научно-исследовательский институт эпидемиологииРоссияI.M. Sechenov First Moscow State Medical University (Sechenov University) ; Central Research Institute of EpidemiologyRussian FederationНИИ педиатрии и охраны здоровья детей НКЦ №2 ФГБНУ «РНЦХ им. акад. Б.В. Петровского»РоссияPediatrics and Child Health Research Institute in Petrovsky National Research Centre of SurgeryRussian FederationСанкт-Петербургский государственный педиатрический медицинский университет ; Белгородский государственный национальный исследовательский университетРоссияSaint Petersburg State Pediatric Medical University ; Belgorod State National Research UniversityRussian FederationРоссийская медицинская академия непрерывного профессионального образования ; Детская городская клиническая больница им З.А. БашляевойРоссияRussian Medical Academy of Continuous Professional Education ; Z.A. Bashlyaeva Children’s City Clinical HospitalRussian FederationРоссийская медицинская академия непрерывного профессионального образованияРоссияRussian Medical Academy of Continuous Professional EducationRussian FederationПервый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет) ; Северо-Осетинская государственная медицинская академияРоссияI.M. Sechenov First Moscow State Medical University (Sechenov University) ; North Ossetian State Medical AcademyRussian FederationВоронежский государственный медицинский университет им. Н.Н. БурденкоРоссияN.N. Burdenko Voronezh State Medical UniversityRussian FederationФедеральный научно-клинический центр специализированных видов медицинской помощи и медицинских технологийРоссияFederal Scientific and Clinical Center for Specialized Types of Medical Care and Medical TechnologiesRussian FederationСтавропольский государственный медицинский университетРоссияStavropol State Medical UniversityRussian FederationСанкт-Петербургский государственный педиатрический медицинский университетРоссияSaint Petersburg State Pediatric Medical UniversityRussian FederationМедико-генетический научный центр им. акад. Н.П. Бочкова ; Научно-исследовательский клинический институт детстваРоссияResearch Centre of Medical Genetics ; Research Clinical Institute of Childhood, Ministry of HealthRussian FederationМедико-генетический научный центр им. акад. Н.П. БочковаРоссияResearch Centre of Medical GeneticsRussian FederationМедико-генетический научный центр им. акад. Н.П. Бочкова ; Сибирский государственный медицинский университетРоссияResearch Centre of Medical Genetics ; Siberian State Medical UniversityRussian FederationДонецкий государственный медицинский университет им. М. ГорькогоРоссияM. Gorkiy Donetsk State Medical UniversityRussian FederationНаучно-исследовательский клинический институт детстваРоссияResearch Clinical Institute of Childhood, Ministry of HealthRussian FederationНИИ педиатрии и охраны здоровья детей НКЦ №2 ФГБНУ «РНЦХ им. акад. Б.В. Петровского» ; Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет) ; Российский национальный исследовательский медицинский университет им. Н.И. Пирогова (Пироговский Университет)РоссияPediatrics and Child Health Research Institute in Petrovsky National Research Centre of Surgery ; I.M. Sechenov First Moscow State Medical University (Sechenov University) ; Pirogov Russian National Research Medical UniversityRussian FederationНациональная ассоциация «Жизнь без глютена»РоссияNational Association “Gluten-Free Life”Russian FederationНИИ педиатрии и охраны здоровья детей НКЦ №2 ФГБНУ «РНЦХ им. акад. Б.В. Петровского» ; Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет) ; Российский национальный исследовательский медицинский университет им. Н.И. Пирогова (Пироговский Университет)РоссияPediatrics and Child Health Research Institute in Petrovsky National Research Centre of Surgery ; I.M. Sechenov First Moscow State Medical University (Sechenov University) ; Pirogov Russian National Research Medical UniversityRussian FederationПервый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет)РоссияI.M. Sechenov First Moscow State Medical University (Sechenov University)Russian FederationНациональный медицинский исследовательский центр здоровья детейРоссияNational Medical Research Center of Children’s HealthRussian FederationНаучно-исследовательский клинический институт детства ; Белгородский государственный национальный исследовательский университетРоссияResearch Clinical Institute of Childhood, Ministry of Health ; Belgorod State National Research UniversityRussian FederationПервый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет) ; Научно-исследовательский клинический институт детстваРоссияI.M. Sechenov First Moscow State Medical University (Sechenov University) ; Research Clinical Institute of Childhood, Ministry of HealthRussian FederationСибирский государственный медицинский университетРоссияSiberian State Medical UniversityRussian Federation202506102025224495522Copyright © Аверкина Н.А., Баранов А.А., Бельмер С.В., Бораева Т.Т., Боровик Т.Э., Бушуева Т.В., Вишнёва Е.А., Горелов А.В., Гундобина О.С., Гурова М.М., Дмитриева Ю.А., Захарова И.Н., Звонкова Н.Г., Звягин А.А., Зокиров Н.З., Кайтукова Е.В., Климов Л.Я., Комарова Е.В., Корниенко Е.А., Кондратьева Е.И., Курьянинова В.А., Куцев С.И., Лохматов М.М., Лошкова Е.В., Налетов А.В., Намазова-Баранова Л.С., Новикова В.П., Одинаева Н.Д., Платонова М.М., Потапов А.С., Ревнова М.О., Романовская И.Э., Рославцева Е.А., Селимзянова Л.Р., Сичинава И.В., Скворцова В.А., Сурков А.Н., Тепаев Р.Ф., Фисенко А.П., Хавкин А.И., Яблокова Е.А., Янкина Г.Н., Эфендиева К.Е., 20252025Аверкина Н.А., Баранов А.А., Бельмер С.В., Бораева Т.Т., Боровик Т.Э., Бушуева Т.В., Вишнёва Е.А., Горелов А.В., Гундобина О.С., Гурова М.М., Дмитриева Ю.А., Захарова И.Н., Звонкова Н.Г., Звягин А.А., Зокиров Н.З., Кайтукова Е.В., Климов Л.Я., Комарова Е.В., Корниенко Е.А., Кондратьева Е.И., Курьянинова В.А., Куцев С.И., Лохматов М.М., Лошкова Е.В., Налетов А.В., Намазова-Баранова Л.С., Новикова В.П., Одинаева Н.Д., Платонова М.М., Потапов А.С., Ревнова М.О., Романовская И.Э., Рославцева Е.А., Селимзянова Л.Р., Сичинава И.В., Скворцова В.А., Сурков А.Н., Тепаев Р.Ф., Фисенко А.П., Хавкин А.И., Яблокова Е.А., Янкина Г.Н., Эфендиева К.Е.Averkina N.A., Baranov A.A., Bel’mer S.V., Boraeva T.T., Borovik T.A., Bushueva T.V., Vishneva E.A., Gorelov A.V., Gundobina O.S., Gurova M.M., Dmitrieva Y.A., Zakharova I.N., Zvonkova N.G., Zvyagin A.A., Zokirov N.Z., Kaytukova E.V., Klimov L.Y., Komarova E.V., Kornienko E.A., Kondratieva E.I., Kuryaninova V.A., Kutsev S.I., Lokhmatov M.M., Loshkova E.V., Nalyotov A.V., Namazova-Baranova L.S., Novikova V.P., Odinaeva N.D., Platonova M.M., Potapov A.S., Revnova M.O., Romanovskaya I.E., Roslavtseva E.A., Selimzyanova L.R., Sichinava I.V., Skvortsova V.A., Surkov A.N., Tepaev R.F., Fisenko A.P., Khavkin A.I., Yablokova E.A., Yankina G.N., Efendieva K.E.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.pedpharma.ru/jour/article/view/2677

Авторами представлены современные данные об этиологии, патогенезе, особенностях клинических проявлений целиакии у детей различного возраста, ассоциированных заболеваниях, методах лабораторно-инструментальной и морфологической диагностики, диетотерапии и дополнительных методах лечения, вакцинации, катамнестическом наблюдении детей с целиакией на основе разработанного проекта клинических рекомендаций «Целиакия. Дети».

The authors present current data on the etiology, pathogenesis, clinical manifestations of celiac disease in children of different ages, associated diseases, laboratory and instrumental diagnostics, diet therapy, additional treatment methods, vaccination, and follow-up of children with celiac disease based on the developed clinical guidelines “Celiac Disease. Children”.

целиакияглютенэзофагогастродуоденоскопиятканевая трансглутаминазабезглютеновая диетаклинические рекомендациидетиceliac diseaseglutenesophagogastroduodenoscopytissue transglutaminasegluten-free dietclinical guidelineschildrenОтсутствует.Not specified.ReferencesHusby S, Koletzko S, Korponay-Szabo IR, et al. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition Guidelines for the Diagnosis of Coeliac Disease. J Pediatr Gastroenterol Nutr. 2012;54(1):136–160. doi: https://doi.org/10.1097/MPG.0b013e31821a23d0Husby S, Koletzko S, Korponay-Szabo IR, et al. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition Guidelines for the Diagnosis of Coeliac Disease. J Pediatr Gastroenterol Nutr. 2012;54(1):136–160. doi: https://doi.org/10.1097/MPG.0b013e31821a23d0Husby S, Koletzko S, Korponay-Szabó I, et al. European Society Paediatric Gastroenterology, Hepatology and Nutrition Guidelines for Diagnosing Coeliac Disease 2020. 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The authors declare that there are no conflicts of interest present.