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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ppharm</journal-id><journal-title-group><journal-title xml:lang="ru">Педиатрическая фармакология</journal-title><trans-title-group xml:lang="en"><trans-title>Pediatric pharmacology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-5776</issn><issn pub-type="epub">2500-3089</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/pf.v22i4.2938</article-id><article-id custom-type="elpub" pub-id-type="custom">ppharm-2676</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ РЕКОМЕНДАЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL RECOMMENDATIONS</subject></subj-group></article-categories><title-group><article-title>Современные рекомендации по ведению пациентов с бронхиальной астмой</article-title><trans-title-group xml:lang="en"><trans-title>Asthma Management Current Guidelines</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5999-2150</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Авдеев</surname><given-names>C. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Avdeev</surname><given-names>Sergey N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва </p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Айсанов</surname><given-names>З. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Aysanov</surname><given-names>Zaurbek R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5671-3478</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Архипов</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Arkhipov</surname><given-names>Vladimir V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7691-4584</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Астафьева</surname><given-names>Н. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Astaphieva</surname><given-names>Nataliya G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Саратов</p></bio><bio xml:lang="en"><p>Saratov</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3987-8112</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баранов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Baranov</surname><given-names>Aleksander A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6050-724X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белевский</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Belevskiy</surname><given-names>Andrey S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8317-2718</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бухтияров</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bukhtiyarov</surname><given-names>Igor V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильева</surname><given-names>О. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasilyeva</surname><given-names>Olga S.</given-names></name></name-alternatives><bio xml:lang="ru"><p> </p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7398-0562</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вишнева</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Vishneva</surname><given-names>Elena A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-7"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0547-3686</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Геппе</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Geppe</surname><given-names>Nataliya A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-8"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8982-5292</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Демко</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Demko</surname><given-names>Irina V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Красноярск</p></bio><bio xml:lang="en"><p>Krasnoyarsk</p></bio><xref ref-type="aff" rid="aff-9"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8574-6869</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Емельянов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Emel’yanov</surname><given-names>Aleksander V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Saint Petersburg</p></bio><xref ref-type="aff" rid="aff-10"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0877-6554</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Игнатова</surname><given-names>Г. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Ignatova</surname><given-names>Galina L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Челябинск</p></bio><bio xml:lang="en"><p>Chelyabinsk</p></bio><xref ref-type="aff" rid="aff-11"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3556-969X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ильина</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Il’ina</surname><given-names>Nataliya I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-12"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Княжеская</surname><given-names>Н. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Knyazheskaya</surname><given-names>Nadezhda P.</given-names></name></name-alternatives><bio xml:lang="ru"><p> </p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3250-0694</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Курбачева</surname><given-names>О. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kurbacheva</surname><given-names>Oksana M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-13"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2460-7718</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Левина</surname><given-names>Ю. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Levina</surname><given-names>Yulia G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-7"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1620-7159</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лещенко</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Leshchenko</surname><given-names>Igor V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Екатеринбург</p></bio><bio xml:lang="en"><p>Yekaterinburg </p></bio><xref ref-type="aff" rid="aff-14"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2686-8284</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Малахов</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Malakhov</surname><given-names>Aleksander B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-8"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мещерякова</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Meshcheryakova</surname><given-names>Nataliya N.</given-names></name></name-alternatives><bio xml:lang="ru"><p> </p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-15"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2209-7531</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Намазова-Баранова</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Namazova-Baranova</surname><given-names>Leyla S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-7"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3162-2510</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ненашева</surname><given-names>Н. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Nenasheva</surname><given-names>Nataliya M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7571-5460</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Новик</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Novik</surname><given-names>Gennadiy A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Saint Petersburg</p></bio><xref ref-type="aff" rid="aff-16"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4164-4094</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Павлова</surname><given-names>К. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Pavlova</surname><given-names>Kseniya S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-12"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5039-8473</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пампура</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Pampura</surname><given-names>Aleksander N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3678-7939</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Селимзянова</surname><given-names>Л. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Selimzyanova</surname><given-names>Liliya R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Селимзянова Лилия Робертовна, кандидат медицинских наук, заведующая отделом стандартизации и изучения основ доказательной медицины НИИ педиатрии и охраны здоровья детей; врач-пульмонолог </p><p>119333, Москва, ул. Фотиевой, д. 10, тел.: +7 (499) 400-47-33 </p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">lilysir@mail.ru</email><xref ref-type="aff" rid="aff-17"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2291-6453</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стрижаков</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Strizhakov</surname><given-names>Leonid A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-8"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5083-6637</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фомина</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Fomina</surname><given-names>Dariya S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-18"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2397-5172</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хаитов</surname><given-names>М. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Haitov</surname><given-names>Musa R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-19"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6808-5528</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чучалин</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Chuchalin</surname><given-names>Aleksander G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6098-7028</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шишиморов</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Shishimorov</surname><given-names>Ivan N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Волгоград</p></bio><bio xml:lang="en"><p>Volgograd</p></bio><xref ref-type="aff" rid="aff-20"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0871-7551</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шпагина</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shpagina</surname><given-names>Lubov A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Новосибирск</p></bio><bio xml:lang="en"><p>Novosibirsk</p></bio><xref ref-type="aff" rid="aff-21"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0317-2425</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Эфендиева</surname><given-names>К. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Efendieva</surname><given-names>Kamilla E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-7"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский институт пульмонологии ; Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Pulmonology ; Sechenov First Moscow State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Российский национальный исследовательский медицинский университет им. Н.И. Пирогова (Пироговский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Российская медицинская академия непрерывного профессионального образования</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Continuing Professional Education</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Саратовский государственный медицинский университет им. В.И. Разумовского</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Razumovskiy Saratov State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет) ; НИИ педиатрии и охраны здоровья детей НКЦ №2 ФГБНУ «РНЦХ им. акад. Б.В. Петровского»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sechenov First Moscow State Medical University ; Research Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of Surgery</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>Научно-исследовательский институт медицины труда им. акад. Н.Ф. Измерова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Izmerov Research Institute of Occupational Health</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-7"><aff xml:lang="ru"><institution>Российский национальный исследовательский медицинский университет им. Н.И. Пирогова (Пироговский Университет) ; НИИ педиатрии и охраны здоровья детей НКЦ №2 ФГБНУ «РНЦХ им. акад. Б.В. Петровского»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University ; Research Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of Surgery</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-8"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sechenov First Moscow State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-9"><aff xml:lang="ru"><institution>Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-10"><aff xml:lang="ru"><institution>Северо-Западный государственный медицинский университет им. И.И. Мечникова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.I. Mechnikov North-Western State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-11"><aff xml:lang="ru"><institution>Южно-Уральский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>South Ural State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-12"><aff xml:lang="ru"><institution>Государственный научный центр «Институт иммунологии»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Government Research Centre “Institute of Immunology”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-13"><aff xml:lang="ru"><institution>Государственный научный центр «Институт иммунологии» ;  Московский государственный медико-стоматологический университет им. А.И. Евдокимова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Government Research Centre “Institute of Immunology” ; A.I. Evdokimov Moscow State University of Medicine and Dentistry</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-14"><aff xml:lang="ru"><institution>Уральский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ural State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-15"><aff xml:lang="ru"><institution>Научно-исследовательский институт пульмонологии</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Pulmonology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-16"><aff xml:lang="ru"><institution>Санкт-Петербургский государственный педиатрический медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint Petersburg State Pediatric Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-17"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет) ;  Российский национальный исследовательский медицинский университет им. Н.И. Пирогова (Пироговский Университет) ; НИИ педиатрии и охраны здоровья детей НКЦ №2 ФГБНУ «РНЦХ им. акад. Б.В. Петровского»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sechenov First Moscow State Medical University ; Pirogov Russian National Research Medical University ; Research Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of Surgery</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-18"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет) ; Городская клиническая больница № 52</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sechenov First Moscow State Medical University ; City Clinical Hospital No. 52</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-19"><aff xml:lang="ru"><institution>Российский национальный исследовательский медицинский университет им. Н.И. Пирогова (Пироговский Университет) ; Государственный научный центр «Институт иммунологии»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University ; Government Research Centre “Institute of Immunology”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-20"><aff xml:lang="ru"><institution>Волгоградский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Volgograd State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-21"><aff xml:lang="ru"><institution>Новосибирский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>06</day><month>10</month><year>2025</year></pub-date><volume>22</volume><issue>4</issue><fpage>432</fpage><lpage>494</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Авдеев C.Н., Айсанов З.Р., Архипов В.В., Астафьева Н.Г., Баранов А.А., Белевский А.С., Бухтияров И.В., Васильева О.С., Вишнева Е.А., Геппе Н.А., Демко И.В., Емельянов А.В., Игнатова Г.Л., Ильина Н.И., Княжеская Н.П., Курбачева О.М., Левина Ю.Г., Лещенко И.В., Малахов А.Б., Мещерякова Н.Н., Намазова-Баранова Л.С., Ненашева Н.М., Новик Г.А., Павлова К.С., Пампура А.Н., Селимзянова Л.Р., Стрижаков Л.А., Фомина Д.С., Хаитов М.Р., Чучалин А.Г., Шишиморов И.Н., Шпагина Л.А., Эфендиева К.Е., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Авдеев C.Н., Айсанов З.Р., Архипов В.В., Астафьева Н.Г., Баранов А.А., Белевский А.С., Бухтияров И.В., Васильева О.С., Вишнева Е.А., Геппе Н.А., Демко И.В., Емельянов А.В., Игнатова Г.Л., Ильина Н.И., Княжеская Н.П., Курбачева О.М., Левина Ю.Г., Лещенко И.В., Малахов А.Б., Мещерякова Н.Н., Намазова-Баранова Л.С., Ненашева Н.М., Новик Г.А., Павлова К.С., Пампура А.Н., Селимзянова Л.Р., Стрижаков Л.А., Фомина Д.С., Хаитов М.Р., Чучалин А.Г., Шишиморов И.Н., Шпагина Л.А., Эфендиева К.Е.</copyright-holder><copyright-holder xml:lang="en">Avdeev S.N., Aysanov Z.R., Arkhipov V.V., Astaphieva N.G., Baranov A.A., Belevskiy A.S., Bukhtiyarov I.V., Vasilyeva O.S., Vishneva E.A., Geppe N.A., Demko I.V., Emel’yanov A.V., Ignatova G.L., Il’ina N.I., Knyazheskaya N.P., Kurbacheva O.M., Levina Y.G., Leshchenko I.V., Malakhov A.B., Meshcheryakova N.N., Namazova-Baranova L.S., Nenasheva N.M., Novik G.A., Pavlova K.S., Pampura A.N., Selimzyanova L.R., Strizhakov L.A., Fomina D.S., Haitov M.R., Chuchalin A.G., Shishimorov I.N., Shpagina L.A., Efendieva K.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pedpharma.ru/jour/article/view/2676">https://www.pedpharma.ru/jour/article/view/2676</self-uri><abstract><p>Клинические рекомендации по бронхиальной астме представляют собой изложение систематизированного подхода к диагностике и лечению этого хронического воспалительного заболевания дыхательных путей для достижения контроля над ним. В статье подробно описаны современные методы диагностики, включая анамнез, физикальное обследование, функциональные пробы легких и определение уровня воспаления. Особое внимание уделяется индивидуализации терапии с учетом степени тяжести и контроля над заболеванием, а также наличия сопутствующих состояний. Авторами подчеркивается важность использования ингаляционных глюкокортикоидов как основы долгосрочного контроля и назначения бронхолитиков быстрого действия для симптоматического облегчения. Также рассматриваются нефармакологические меры: избегание контакта с аллергенами, изменение образа жизни, обучение пациентов правильному использованию ингаляторов и самостоятельному контролю за симптомами. Важной частью являются стратегия «поддерживающей терапии» и план действий при обострениях, что способствует своевременному реагированию и снижению риска тяжелых состояний. Авторы подчеркивают необходимость регулярного мониторинга эффективности лечения и коррекции терапии в зависимости от динамики заболевания. Данные клинические рекомендации направлены на повышение качества медицинской помощи пациентам с бронхиальной астмой, снижение частоты обострений болезни и улучшение качества жизни больных за счет внедрения современных доказательных методов диагностики и терапии.</p></abstract><trans-abstract xml:lang="en"><p>The clinical guidelines for asthma provide a systematic approach to the diagnosis and treatment of this chronic inflammatory disease of the respiratory tract. The article provides a detailed description of current diagnostic methods, including history taking, physical examination, pulmonary function tests, and inflammation measurements. The focus is on individualizing therapy based on the severity and control of the disease, as well as the presence of comorbidities. The authors emphasize the importance of using inhaled corticosteroids as the foundation for long-term control and the use of fast-acting bronchodilators for symptomatic relief. The guidelines also cover non-pharmacological measures, such as avoiding allergens, lifestyle changes, and teaching patients how to properly use inhalers and monitor their symptoms. An important aspect of the guidelines is the “supportive therapy” strategy and the plan of action for exacerbations, which helps to respond promptly and reduce the risk of severe conditions. The guidelines emphasize the need for regular monitoring of treatment effectiveness and the adjustment of therapy based on the progression of the disease. The goal of these clinical guidelines is to improve the quality of care for patients with asthma, reduce the frequency of exacerbations, and enhance their quality of life through the implementation of evidencebased diagnostic and treatment methods.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>бронхиальная астма</kwd><kwd>клинические рекомендации</kwd><kwd>терапия</kwd><kwd>диагностика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>children</kwd><kwd>asthma</kwd><kwd>clinical guidelines</kwd><kwd>management</kwd><kwd>diagnostics</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Не указано.</funding-statement><funding-statement xml:lang="en">Not  specified.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ray A, Camiolo M, Fitzpatrick A, et al. Are We Meeting the Promise of Endotypes and Precision Medicine in Asthma? 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