ppharmПедиатрическая фармакологияPediatric pharmacology1727-57762500-3089Издательство «ПедиатрЪ»10.15690/pf.v10i1.584ppharm-260Research ArticleВАКЦИНАЦИЯ В СОВРЕМЕННОМ МИРЕVACCINATIONРАСШИРЕНИЕ ВОЗМОЖНОСТЕЙ ВАКЦИНОПРОФИЛАКТИКИ ПАПИЛЛОМАВИРУСНОЙ (ВПЧ)-ИНФЕКЦИИ: ЗАЩИТА ОТ ЦЕЛОГО СПЕКТРА ВПЧ-АССОЦИИРОВАННЫХ ЗАБОЛЕВАНИЙ ЛИЦ РАЗЛИЧНОГО ВОЗРАСТА И ПОЛАENHANCING VACCINAL PREVENTION OF THE HUMAN PAPILLOMA VIRAL (HPV) INFECTION: PROTECTING PEOPLE OF DIFFERENT AGE AND SEX FROM A RANGE OF HPV-ASSOCIATED DISEASESГалицкаяМ. Г.GalitskayaM. G.

кандидат медицинских наук, заведующая отделением вакцинопрофилактики детей с отклонениями в состоянии здоровья ФГБУ «НЦЗД» РАМН

MD, head of the vaccinal prevention department for children with medical issues at the FSBI RAMS “SCCH”

galitskaya@nczd.ruГайворонскаяА. Г.GayvoronskayaA. G.Научный центр здоровья детей РАМН, Москва, Российская ФедерацияScientific Center of Children’s Health, Moscow, Russian Federation201313022013101Педиатрическая фармакология1317Copyright © Галицкая М.Г., Гайворонская А.Г., 20132013Галицкая М.Г., Гайворонская А.Г.Galitskaya M.G., Gayvoronskaya A.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.pedpharma.ru/jour/article/view/260

ВПЧ — самая распространенная инфекция, передаваемая половым путем. ВПЧ поражает мужчин и женщин независимо от возраста и приводит к развитию различных заболеваний аногенитальной области. Проведенные международные клинические исследования подтвердили широкий спектр защиты четырехвалентной вакцины против ВПЧ и позволили рекомендовать ее для профилактики не только рака шейки матки, но и рака вульвы, влагалища, анального канала и аногенитальных кондилом у лиц обоих полов. 42 страны уже внедрили национальные программы ВПЧ-вакцинации в соответствии с рекомендациями ВОЗ. Снижение заболеваемости раком аногенитальной области в этих странах ожидается через 10–15 лет. Однако уже сейчас в ряде стран отмечается снижение или даже полное исчезновение аногенитальных кондилом среди населения, что связано с коротким инкубационным периодом данного заболевания и является первым маркером эффективности вакцинации в популяции.

HPV is the most widespread sexually transmitted infection. HPV affects men and women regardless of age and leads to the development of various anogenital area diseases. International studies proved a wide clinical range of the tetravalent HPV vaccine protection and allowed recommending it for the prevention of not only cervical cancer, but also of vulvar, vaginal and anal cancer and anogenital condylomae in patients of both sexes. 42 countries have already introduced national HPV-vaccination programs in compliance with WHO recommendations. Anogenital area cancer morbidity reduction in these countries is expected in 10-15 years. However, a reduction or even complete disappearance of anogenital condylomae among the population has already been noted in a range of countries because the incubation period of this disease is short; this is the first marker of vaccination efficacy in a population.

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The authors declare that there are no conflicts of interest present.