ppharmПедиатрическая фармакологияPediatric pharmacology1727-57762500-3089Издательство «ПедиатрЪ»10.15690/pf.v22i2.2882ppharm-2598Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEWЦелиакия и расстройства пищевого поведения — двунаправленная взаимосвязь заболеванийCeliac Disease and Eating Disorders are a Bidirectional Relationship of Diseaseshttps://orcid.org/0000-0001-7308-7280ХавкинА. И.KhavkinAnatoly I.

Хавкин Анатолий Ильич, доктор медицинских наук, профессор, руководитель Московского областного центра детской гастроэнтерологии и гепатологии Научно-исследовательского клинического института детства, профессор кафедры педиатрии Медицинского института Белгородского государственного национального исследовательского университета

Адрес: 115093, Москва, ул. Большая Серпуховская, д. 62, тел.: +7 (499) 237-02-23

Anatoly I. Khavkin, MD, PhD, Professor

62, Bolshaya Serpukhovskaya Str., Moscow, 115093

gastropedclin@gmail.ruhttps://orcid.org/0000-0001-5214-8072ОдинаеваН. Д.OdinaevaNuriniso D.

Одинаева Нуриниcо Джумаевна, д.м.н., профессор

Москва

Nuriniso D. Odinaeva, MD, PhD, Professor

Moscow

nig05@mail.ruhttps://orcid.org/0000-0002-4733-3262НалетовА. В.NalyotovAndrew V.

Налетов Андрей Васильевич, д.м.н.

Донецк

Andrew V. Nalyotov, MD, PhD, Professor

Donetsk

nalyotov-a@mail.ruhttps://orcid.org/0000-0001-6395-0407КондратьеваЕ. И.KondratyevaElena I.

Кондратьева Елена Ивановна, д.м.н.

Москва

Elena I. Kondratyeva, MD, PhD, Professor

Moscow

elenafpk@mail.ruhttps://orcid.org/0000-0001-5070-9606МарченкоН. А.MarchenkoNataliya A.

Марченко Наталия Александровна

Донецк

Nataliya A. Marchenko, MD

Donetsk

nataliiasvistunova@yandex.ruhttps://orcid.org/0000-0002-2547-6377МацынинА. Н.MatsyninAlexander N.

Мацынин Александр Николаевич, д.м.н., доцент

Донецк

Alexander N. Matsynin, MD, PhD, Associate professor

Donetsk

anmatsynin@yandex.ruhttps://orcid.org/0000-0003-3364-610XЯблоковаЕ. А.YablokovaEkaterina A.

Яблокова Екатерина Александровна, к.м.н.

Москва

Ekaterina A. Yablokova, MD, PhD

Moscow

https://orcid.org/0009-0005-7887-8168ЗавражнаяК. Д.ZavrazhnayaKristina D.

Завражная Кристина Дмитриевна

Москва

Kristina D. Zavrazhnaya, MD

Moscow

kristina_zavrazhnaya@mail.ruНаучно-исследовательский клинический институт детства; Белгородский государственный национальный исследовательский университетРоссияResearch and Clinical Institute for Children; Belgorod State National Research UniversityRussian FederationНаучно-исследовательский клинический институт детстваРоссияResearch and Clinical Institute for ChildrenRussian FederationДонецкий государственный медицинский университет им. М. ГорькогоРоссияM.Gorky Donetsk National Medical UniversityRussian FederationНаучно-исследовательский клинический институт детства; Медико-генетический научный центр им. акад. Н.П. БочковаРоссияResearch and Clinical Institute for Children; Research Centre for Medical GeneticsRussian FederationНаучно-исследовательский клинический институт детства; Первый Московский государственный университет им. И.М. Сеченова (Сеченовский Университет)РоссияResearch and Clinical Institute for Children; Sechenov Moscow Medical AcademyRussian Federation202523052025222135140Copyright © Хавкин А.И., Одинаева Н.Д., Налетов А.В., Кондратьева Е.И., Марченко Н.А., Мацынин А.Н., Яблокова Е.А., Завражная К.Д., 20252025Хавкин А.И., Одинаева Н.Д., Налетов А.В., Кондратьева Е.И., Марченко Н.А., Мацынин А.Н., Яблокова Е.А., Завражная К.Д.Khavkin A.I., Odinaeva N.D., Nalyotov A.V., Kondratyeva E.I., Marchenko N.A., Matsynin A.N., Yablokova E.A., Zavrazhnaya K.D.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.pedpharma.ru/jour/article/view/2598

Целиакия и расстройства пищевого поведения являются сложными хроническими заболеваниями, которые характеризуются изменением массы тела, недостаточностью питания и гастроинтестинальными симптомами. Терапия пациентов, страдающих целиакией, проводится путем соблюдения строгой безглютеновой диеты, которая может непреднамеренно способствовать нарушению пищевого поведения. И, наоборот, расстройства пищевого поведения могут маскировать и отягощать клинические проявления целиакии, что приводит к пролонгации сроков диагностики заболевания и проблемам с лечением таких пациентов. Имеющиеся данные указывают на повышенный риск развития расстройств пищевого поведения у пациентов с целиакией и наоборот, что говорит о потенциальной двунаправленной взаимосвязи данных заболеваний. В представленном обзоре рассматриваются механизмы и клинические последствия взаимосвязи целиакии и расстройств пищевого поведения, а также предлагаются стратегии комплексного скрининга и лечения для улучшения качества жизни пациентов с обоими состояниями.

Celiac disease and eating disorders are complex chronic diseases characterized by weight changes, malnutrition, and gastrointestinal symptoms. Celiac disease patients are treated by following a strict gluten-free diet, which may inadvertently contribute to eating disorders. Conversely, eating disorders can mask and aggravate the clinical manifestations of celiac disease, which leads to a prolongation of the diagnosis of the disease and problems with the treatment of such patients. The available data indicate an increased risk of developing eating disorders in patients with celiac disease and vice versa, suggesting a potential bidirectional relationship between these diseases. This review examines the mechanisms and clinical consequences of the interaction between celiac disease and eating disorders, and suggests strategies for comprehensive screening and treatment to improve the quality of life of patients with both conditions.

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The authors declare that there are no conflicts of interest present.