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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ppharm</journal-id><journal-title-group><journal-title xml:lang="ru">Педиатрическая фармакология</journal-title><trans-title-group xml:lang="en"><trans-title>Pediatric pharmacology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-5776</issn><issn pub-type="epub">2500-3089</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/pf.v21i5.2819</article-id><article-id custom-type="elpub" pub-id-type="custom">ppharm-2527</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Современные подходы к достижению контроля над распространенными нарушениями здоровья у младенцев: эффективность высокогидролизованных и аминокислотных формул</article-title><trans-title-group xml:lang="en"><trans-title>Modern Approaches to Achieving Control over Common Health Disorders in Infants: the Effectiveness of Extensively Hydrolyzed and Amino Acid Formulas</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7398-0562</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вишнева</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Vishneva</surname><given-names>Elena A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Вишнева Елена Александровна, доктор медицинских наук, профессор РАН, заместитель руководителя по науке, врач аллерголог-иммунолог НИИ педиатрии и охраны здоровья детей НКЦ №2 ФГБНУ «РНЦХ им. акад. Б.В. Петровского» Минобрнауки России, профессор кафедры факультетской педиатрии Института материнства и детства ФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России</p><p>119333, Москва, ул. Фотиевой, д. 10, стр. 1</p></bio><bio xml:lang="en"><p>Elena A. Vishneva, MD, PhD, Professor of the RAS</p><p>10, Fotievoy Str., building 1, Moscow, 119333</p><p> </p></bio><email xlink:type="simple">vishneva.e@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3598-9600</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чемакина</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Chemakina</surname><given-names>Darya S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чемакина Дарья Сергеевна, к.м.н.</p><p>Москва, Тюмень</p></bio><bio xml:lang="en"><p>Darya S. Chemakina, MD, PhD</p><p>Moscow, Tyumen</p></bio><email xlink:type="simple">daria06ch@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2460-7718</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Левина</surname><given-names>Ю. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Levina</surname><given-names>Yulia G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Левина Юлия Григорьевна, к.м.н. </p><p>Москва</p></bio><bio xml:lang="en"><p>Yulia G. Levina, MD, PhD</p><p>Moscow</p></bio><email xlink:type="simple">julia.levina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0317-2425</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Эфендиева</surname><given-names>К. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Efendieva</surname><given-names>Kamilla E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Эфендиева Камилла Евгеньевна, к.м.н. </p><p>Москва</p></bio><bio xml:lang="en"><p>Kamilla E. Efendieva, MD, PhD</p><p>Moscow</p></bio><email xlink:type="simple">kamillaef@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3781-8661</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Калугина</surname><given-names>В. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kalugina</surname><given-names>Vera G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Калугина Вера Геннадьевна, к.м.н. </p><p>Москва</p></bio><bio xml:lang="en"><p>Vera G. Kalugina, MD, PhD</p><p>Moscow</p></bio><email xlink:type="simple">v-starikova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5665-7835</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеева</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekseeva</surname><given-names>Anna A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алексеева Анна Александровна, к.м.н. </p><p>Москва</p></bio><bio xml:lang="en"><p>Anna A. Alekseeva, MD, PhD</p><p>Moscow</p></bio><email xlink:type="simple">aleksaa06@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3678-7939</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Селимзянова</surname><given-names>Л. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Selimzyanova</surname><given-names>Liliya R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Селимзянова Лилия Робертовна, к.м.н. </p><p>Москва</p></bio><bio xml:lang="en"><p>Liliya R. Selimzyanova, MD, PhD</p><p>Moscow</p></bio><email xlink:type="simple">lilysir@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8936-3590</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кайтукова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kaitukova</surname><given-names>Elena V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кайтукова Елена Владимировна, к.м.н. </p><p>Москва</p></bio><bio xml:lang="en"><p>Elena V. Kaitukova, MD, PhD</p><p>Moscow</p></bio><email xlink:type="simple">dr.gastro@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2482-9289</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баранник</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Barannik</surname><given-names>Vladimir A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Баранник Владимир Алексеевич, к.м.н. </p><p>Москва</p></bio><bio xml:lang="en"><p>Vladimir A. Barannik, MD, PhD</p><p>Moscow</p></bio><email xlink:type="simple">vladimirbarannik@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>НИИ педиатрии и охраны здоровья детей НКЦ №2 ФГБНУ «РНЦХ им. акад. Б.В. Петровского»;&#13;
РНИМУ им. Н.И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of Surgery;&#13;
Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>НИИ педиатрии и охраны здоровья детей НКЦ №2 ФГБНУ «РНЦХ им. акад. Б.В. Петровского»;&#13;
ТюмГМУ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of Surgery;&#13;
Tyumen State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>НИИ педиатрии и охраны здоровья детей НКЦ №2 ФГБНУ «РНЦХ им. акад. Б.В. Петровского»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of Surgery</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>20</day><month>11</month><year>2024</year></pub-date><volume>21</volume><issue>5</issue><fpage>440</fpage><lpage>448</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Вишнева Е.А., Чемакина Д.С., Левина Ю.Г., Эфендиева К.Е., Калугина В.Г., Алексеева А.А., Селимзянова Л.Р., Кайтукова Е.В., Баранник В.А., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Вишнева Е.А., Чемакина Д.С., Левина Ю.Г., Эфендиева К.Е., Калугина В.Г., Алексеева А.А., Селимзянова Л.Р., Кайтукова Е.В., Баранник В.А.</copyright-holder><copyright-holder xml:lang="en">Vishneva E.A., Chemakina D.S., Levina Y.G., Efendieva K.E., Kalugina V.G., Alekseeva A.A., Selimzyanova L.R., Kaitukova E.V., Barannik V.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pedpharma.ru/jour/article/view/2527">https://www.pedpharma.ru/jour/article/view/2527</self-uri><abstract><p>Правильное питание матери и младенца — важнейшее условие развития и здоровья ребенка. Именно первые 1000 дней жизни ребенка критичны для нейроонтогенеза, формирования дальнейших способностей приобретать и совершенствовать различные навыки, успешно обучаться. «Золотым стандартом» питания для всех новорожденных, включая детей с функциональными нарушениями пищеварения и пищевой аллергией, является грудное молоко. Поддержка и продвижение приверженности грудному вскармливанию в первые 6 мес жизни ребенка — важнейшие задачи для всех медицинских работников, оказывающих медицинскую помощь детям. Наиболее распространенными патологическими состояниями среди детей первого года жизни являются функциональные нарушения пищеварения и проявления пищевой аллергии, при которых диетотерапия — основной вид лечения. В ситуациях, когда грудное молоко недоступно такому младенцу, важно осуществить правильный выбор смеси. Современные формулы для искусственного вскармливания новорожденных и грудных детей благодаря особенностям состава обладают целым рядом полезных свойств, максимально приближающих их к грудному молоку, специально разработанных с целью обеспечить полноценное питание и одновременно выполнить терапевтические задачи.</p></abstract><trans-abstract xml:lang="en"><p>Proper nutrition of the mother and baby is the most important condition for the development and health of the child. It is the first 1000 days of a child’s life that are critical for neuroontogenesis, the formation of further abilities to acquire and improve various skills, and to learn successfully. It is the first 1000 days of a child’s life that are critical for neuroontogenesis, the formation of further abilities to acquire and improve various skills, and to learn successfully. Breast milk is the “gold standard” of nutrition for all newborns, including children with functional digestive disorders and food allergies. Supporting and promoting adherence to breastfeeding in the first 6 months of a child’s life are the most important tasks for all medical professionals providing medical care to children. The most common pathological conditions among children of the first year of life are functional digestive disorders and manifestations of food allergies, in which diet therapy is the main type of treatment. In situations where breast milk is not available to such an infant, it is important to make the right choice of formula. Modern formulas for artificial feeding of newborns and infants have a number of useful properties due to the features of the composition, which bring them as close as possible to breast milk, specially designed to provide adequate nutrition and simultaneously perform therapeutic tasks.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>младенцы</kwd><kwd>функциональные  расстройства  пищеварения</kwd><kwd>пищевая  аллергия</kwd><kwd>аллергия к белкам коровьего молока</kwd><kwd>высокогидролизованная смесь</kwd><kwd>аминокислотная смесь</kwd></kwd-group><kwd-group xml:lang="en"><kwd>children</kwd><kwd>infants</kwd><kwd>functional digestive disorders</kwd><kwd>food allergy</kwd><kwd>cow’s milk protein allergy</kwd><kwd>extensively hydrolyzed formula</kwd><kwd>amino acid formula</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Отсутствует.</funding-statement><funding-statement xml:lang="en">Not specified.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Беляева И.А., Намазова-Баранова Л.С., Бомбардирова Е.П. и др. Введение прикорма: «окно возможностей» формирования кишечной микробиоты и модулирования иммунных реакций // Вопросы современной педиатрии. — 2023. — Т. 22. — № 6. — С. 506–512. — doi: https://doi.org/10.15690/vsp.v22i6.2663</mixed-citation><mixed-citation xml:lang="en">Belyaeva IA, Namazova-Baranova LS, Bombardirova EP, et al. Supplemental Feeding Implementation: Window of Opportunities for the Intestinal Microbiota Development and Immune Responses Modulation. Voprosy sovremennoi pediatrii — Current Pediatrics. 2023;22(6):506–512. (In Russ). doi: https://doi.org/10.15690/vsp.v22i6.2663</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Likhar A, Patil MS. Importance of Maternal Nutrition in the First 1,000 Days of Life and Its Effects on Child Development: A Narrative Review. Cureus. 2022;14(10):e30083. doi: https://doi.org/10.7759/cureus.30083</mixed-citation><mixed-citation xml:lang="en">Likhar A, Patil MS. Importance of Maternal Nutrition in the First 1,000 Days of Life and Its Effects on Child Development: A Narrative Review. Cureus. 2022;14(10):e30083. doi: https://doi.org/10.7759/cureus.30083</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">UNICEF. First 1000 Days the critical Window to ensure that children survive and thrive. Published online 2017. Available online: unicef.org›southafrica/media/551/file. Accessed on August 30, 2024.</mixed-citation><mixed-citation xml:lang="en">UNICEF. First 1000 Days the critical Window to ensure that children survive and thrive. Published online 2017. Available online: unicef.org›southafrica/media/551/file. Accessed on August 30, 2024.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Беляева И.А., Бомбардирова Е.П., Намазова-Баранова Л.С. и др. Дизонтогении микробиоты кишечника у детей первых месяцев жизни как фактор формирования атопии // Педиатрическая фармакология. — 2019. — Т. 16. — № 2. — С. 91–96. — doi: https://doi.org/10.15690/pf.v16i2.2005</mixed-citation><mixed-citation xml:lang="en">Belyaeva IA, Bombardirova EP, Namazova-Baranova LS, et al. Gut microbiota dysontogeniya in infants as a factor in the development of atopy. Pediatricheskaya farmakologiya — Pediatric pharmacology. 2019;16(2):91–96. (In Russ). doi: https://doi.org/10.15690/pf.v16i2.2005</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Юрьев В.К., Моисеева К.Е., Алексеева А.В. Основные причины отказов от грудного вскармливания // Социальные аспекты здоровья населения [сетевое издание]. — 2019. — Т. 65. — № 2. — doi: https://doi.org/10.21045/2071-5021-2019-65-2-5</mixed-citation><mixed-citation xml:lang="en">Yurev VK, Moiseeva KE, Alekseeva AV. Main reasons for refusing breastfeeding. Social’nye aspekty zdorov’a naselenia = Social aspects of population health [serial online]. 2019;65(2). (In Russ). doi: https://doi.org/10.21045/2071-5021-2019-65-2-5</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Копанев Ю.А., Соколов А.Л. Алгоритмы, принципы и оптимальные сроки введения адаптированных и специализированных смесей для вскармливания детей грудного возраста // Лечащий Врач. — 2021. — № 2. — С. 49–52. — doi: https://doi.org/10.26295/OS.2021.75.40.010</mixed-citation><mixed-citation xml:lang="en">Kopanev YuA, Sokolov AL. Algorithms, principles and optimal timing of the introduction of adapted and specialized formulas for feeding infants. Lechaschy Vrach. 2021;(2):49–52. (In Russ). doi: https://doi.org/10.26295/OS.2021.75.40.010</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Vandenplas Y, Hauser B, Salvatore S. Functional Gastrointestinal Disorders in Infancy: Impact on the Health of the Infant and Family. Pediatr Gastroenterol Hepatol Nutr. 2019;22(3):207–216. doi: https://doi.org/10.5223/pghn.2019.22.3.207</mixed-citation><mixed-citation xml:lang="en">Vandenplas Y, Hauser B, Salvatore S. Functional Gastrointestinal Disorders in Infancy: Impact on the Health of the Infant and Family. Pediatr Gastroenterol Hepatol Nutr. 2019;22(3):207–216. doi: https://doi.org/10.5223/pghn.2019.22.3.207</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Heine RG, Al Refaee F, Bachina P, et al. Lactose intolerance and gastrointestinal cow’s milk allergy in infants and children — common misconceptions revisited. World Allergy Organ J. 2017;10(1):41. doi: https://doi.org/10.1186/s40413-017-0173-0</mixed-citation><mixed-citation xml:lang="en">Heine RG, Al Refaee F, Bachina P, et al. Lactose intolerance and gastrointestinal cow’s milk allergy in infants and children — common misconceptions revisited. World Allergy Organ J. 2017;10(1):41. doi: https://doi.org/10.1186/s40413-017-0173-0</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Чубарова А.И. Возможности и ограничения расширения показаний для применения смесей на основе высоко гидролизованного белка для детей в возрасте до года // Вопросы детской диетологии. — 2023. — Т. 21. — № 6. — С. 44–57. — doi: https://doi.org/10.20953/1727-5784-2023-6-44-57</mixed-citation><mixed-citation xml:lang="en">Chubarova AI. Opportunities and limitations of expanding indications for extensively hydrolyzed protein formulas for infants. Voprosy detskoi dietologii = Pediatric Nutrition. 2023;21(6):44–57. (In Russ). doi: https://doi.org/10.20953/1727-5784-2023-6-44-57</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Макарова Е.Г., Нетребенко О.К., Украинцев С.Е. Олигосахариды грудного молока: история открытия, структура и защитные функции // Педиатрия. Журнал им. Г.Н. Сперанского. — 2018. — Т. 97. — № 4. — С. 152–160. — doi: https://doi.org/10.24110/0031-403X-2018-97-4-152-160</mixed-citation><mixed-citation xml:lang="en">Makarova EG, Netrebenko OK, Ukraintsev SE. Breast milk oligosaccharides: the history of discovery, structure and protective functions. Pediatria. Journal n.a. G.N. Speransky. 2018;97(4):152–160. (In Russ). doi: https://doi.org/10.24110/0031-403X-2018-97-4-152-160</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Мухаметова Е.М. Олигосахариды грудного молока: участие в иммунных реакциях и потенциальная роль в профилактике аллергических заболеваний // Доктор.Ру. — 2023. — Т. 22. — № 3. — С. 81–88. — doi: https://doi.org/10.31550/1727-2378-2023-22-3-81-88</mixed-citation><mixed-citation xml:lang="en">Mukhametova EM. Breast milk oligosaccharides: their role in immune reactions and potential role in allergy prevention. Doctor.Ru. 2023;22(3):81–88. (In Russ). doi: https://doi.org/10.31550/1727-2378-2023-22-3-81-88</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Bode L. Human milk oligosaccharides: every baby needs a sugar mama. Glycobiology. 2012;22(9):1147–1162. doi: https://doi.org/10.1093/glycob/cws074</mixed-citation><mixed-citation xml:lang="en">Bode L. Human milk oligosaccharides: every baby needs a sugar mama. Glycobiology. 2012;22(9):1147–1162. doi: https://doi.org/10.1093/glycob/cws074</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Soyyılmaz B, Mikš MH, Röhrig CH, et al. The Mean of Milk: A Review of Human Milk Oligosaccharide Concentrations throughout Lactation. Nutrients. 2021;13(8):2737. doi: https://doi.org/10.3390/nu13082737</mixed-citation><mixed-citation xml:lang="en">Soyyılmaz B, Mikš MH, Röhrig CH, et al. The Mean of Milk: A Review of Human Milk Oligosaccharide Concentrations throughout Lactation. Nutrients. 2021;13(8):2737. doi: https://doi.org/10.3390/nu13082737</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Abrahams SW, Labbok MH. Breastfeeding and otitis media: A review of recent evidence. Curr Allergy Asthma Rep. 2011;11(6):508– 512. doi: https://doi.org/10.1007/s11882-011-0218-3</mixed-citation><mixed-citation xml:lang="en">Abrahams SW, Labbok MH. Breastfeeding and otitis media: A review of recent evidence. Curr Allergy Asthma Rep. 2011;11(6):508– 512. doi: https://doi.org/10.1007/s11882-011-0218-3</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Rousseaux A, Brosseau C, Le Gall S, et al. Human Milk Oligosaccharides: Their Effects on the Host and Their Potential as Therapeutic Agents. Front Immunol. 2021;12:680911. doi: https://doi.org/10.3389/fimmu.2021.680911</mixed-citation><mixed-citation xml:lang="en">Rousseaux A, Brosseau C, Le Gall S, et al. Human Milk Oligosaccharides: Their Effects on the Host and Their Potential as Therapeutic Agents. Front Immunol. 2021;12:680911. doi: https://doi.org/10.3389/fimmu.2021.680911</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Goehring KC, Marriage BJ, Oliver JS, et al. Similar to Those Who Are Breastfed, Infants Fed a Formula Containing 2-Fucosyllactose Have Lower Inflammatory Cytokines in a Randomized Controlled Trial. J Nutr. 2016;146(12):2559–2566. doi: https://doi.org/10.3945/jn.116.236919</mixed-citation><mixed-citation xml:lang="en">Goehring KC, Marriage BJ, Oliver JS, et al. Similar to Those Who Are Breastfed, Infants Fed a Formula Containing 2-Fucosyllactose Have Lower Inflammatory Cytokines in a Randomized Controlled Trial. J Nutr. 2016;146(12):2559–2566. doi: https://doi.org/10.3945/jn.116.236919</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Alliet P, Vandenplas Y, Roggero P, et al. Safety and efficacy of a probiotic-containing infant formula supplemented with 2-fucosyllactose: a double-blind randomized controlled trial. Nutr J. 2022;21(1):11. doi: https://doi.org/10.1186/s12937-022-00764-2</mixed-citation><mixed-citation xml:lang="en">Alliet P, Vandenplas Y, Roggero P, et al. Safety and efficacy of a probiotic-containing infant formula supplemented with 2-fucosyllactose: a double-blind randomized controlled trial. Nutr J. 2022;21(1):11. doi: https://doi.org/10.1186/s12937-022-00764-2</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Reverri EJ, Devitt AA, Kajzer JA, et al. Review of the Clinical Experiences of Feeding Infants Formula Containing the Human Milk Oligosaccharide 2-Fucosyllactose. Nutrients. 2018;10(10):1346. doi: https://doi.org/10.3390/nu10101346</mixed-citation><mixed-citation xml:lang="en">Reverri EJ, Devitt AA, Kajzer JA, et al. Review of the Clinical Experiences of Feeding Infants Formula Containing the Human Milk Oligosaccharide 2-Fucosyllactose. Nutrients. 2018;10(10):1346. doi: https://doi.org/10.3390/nu10101346</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Boulangé CL, Pedersen HK, Martin FP, et al. An Extensively Hydrolyzed Formula Supplemented with Two Human Milk Oligosaccharides Modifies the Fecal Microbiome and Metabolome in Infants with Cow’s Milk Protein Allergy. Int J Mol Sci. 2023;24(14):11422. doi: https://doi.org/10.3390/ijms241411422</mixed-citation><mixed-citation xml:lang="en">Boulangé CL, Pedersen HK, Martin FP, et al. An Extensively Hydrolyzed Formula Supplemented with Two Human Milk Oligosaccharides Modifies the Fecal Microbiome and Metabolome in Infants with Cow’s Milk Protein Allergy. Int J Mol Sci. 2023;24(14):11422. doi: https://doi.org/10.3390/ijms241411422</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Czerkies LM, Finn KL, Kineman BD, et al. Use of a Partially Hydrolyzed 100% Whey-Based Infant Formula with Lactobacillus Reuteri in Infants with Caregiver-Perceived Intolerance. J Pediatr Health Nutr. 2019;1(1):19–26. doi: https://doi.org/10.14302/issn.2691-5014.jphn-19-3067</mixed-citation><mixed-citation xml:lang="en">Czerkies LM, Finn KL, Kineman BD, et al. Use of a Partially Hydrolyzed 100% Whey-Based Infant Formula with Lactobacillus Reuteri in Infants with Caregiver-Perceived Intolerance. J Pediatr Health Nutr. 2019;1(1):19–26. doi: https://doi.org/10.14302/issn.2691-5014.jphn-19-3067</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Щербак В.А., Щербак Н.М. Лактазная недостаточность у детей // Педиатрическая фармакология. — 2011. — Т. 8. — № 3. — С. 90–93.</mixed-citation><mixed-citation xml:lang="en">Sherbak VA, Sherbak NM. Lactase deficiency in children. Pediatricheskaya farmakologiya — Pediatric pharmacology. 2011;8(3):90–93. (In Russ).</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Ипатова М.Г., Дубровская М.И., Корнева Т.И. и др. Лактазная недостаточность у детей раннего возраста и особенности питания при патологии. Разбор клинических случаев // Вопросы современной педиатрии. — 2012. — Т. 11. — № 1. — С. 119– 123. — doi: https://doi.org/10.15690/vsp.v11i1.142</mixed-citation><mixed-citation xml:lang="en">Ipatova МG, Dubrovskaya МI, Korneva ТI, et al. Infantile lactase deficiency and dietary habits. Cliunical cases. Voprosy sovremennoi pediatrii — Current Pediatrics. 2012;11(1):119–123. (In Russ). doi: https://doi.org/10.15690/vsp.v11i1.142</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Wauters L, Brown T, Venter C, et al. Cow’s Milk Allergy Prescribing Is Influenced by Regional and National Guidance. J Pediatr Gastroenterol Nutr. 2016;62(5):765–770. doi: https://doi.org/10.1097/MPG.0000000000001052</mixed-citation><mixed-citation xml:lang="en">Wauters L, Brown T, Venter C, et al. Cow’s Milk Allergy Prescribing Is Influenced by Regional and National Guidance. J Pediatr Gastroenterol Nutr. 2016;62(5):765–770. doi: https://doi.org/10.1097/MPG.0000000000001052</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Vandenplas Y, Plaskie K, Hauser B. Safety and adequacy of a semi-elemental formula for children with gastro-intestinal disease. Amino Acids. 2010;38(3):909–914. doi: https://doi.org/10.1007/s00726-009-0298-8</mixed-citation><mixed-citation xml:lang="en">Vandenplas Y, Plaskie K, Hauser B. Safety and adequacy of a semi-elemental formula for children with gastro-intestinal disease. Amino Acids. 2010;38(3):909–914. doi: https://doi.org/10.1007/s00726-009-0298-8</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Cekola P, Henrikson A, Reichert H, et al. Prospective surveillance of an amino-acid based infant formula in infants with cow’s milk protein allergy, in a routine clinical practice setting. Allergy. 2020;75(Suppl 109):120–274. doi: https://doi.org/10.1111/all.14506</mixed-citation><mixed-citation xml:lang="en">Cekola P, Henrikson A, Reichert H, et al. Prospective surveillance of an amino-acid based infant formula in infants with cow’s milk protein allergy, in a routine clinical practice setting. Allergy. 2020;75(Suppl 109):120–274. doi: https://doi.org/10.1111/all.14506</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Steutel NF, Zeevenhooven J, Scarpato E, et al. Prevalence of Functional Gastrointestinal Disorders in European Infants and Toddlers. J Pediatr. 2020;221:107–114. doi: https://doi.org/10.1016/j.jpeds.2020.02.076</mixed-citation><mixed-citation xml:lang="en">Steutel NF, Zeevenhooven J, Scarpato E, et al. Prevalence of Functional Gastrointestinal Disorders in European Infants and Toddlers. J Pediatr. 2020;221:107–114. doi: https://doi.org/10.1016/j.jpeds.2020.02.076</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Украинцев С.Е., Лукушкина Е.Ф., Лазарева Т.С. и др. Олигосахариды грудного молока и пребиотики в питании грудных детей // Педиатрия. Журнал им. Г.Н. Сперанского. — 2007. — Т. 86. — № 6. — С. 75–80.</mixed-citation><mixed-citation xml:lang="en">Ukraintsev SE, Lukushkina EF, Lazareva TS, et al. Breast milk oligosaccharides and prebiotics in feeding of infants. Pediatria. Journal n.a. G.N. Speransky. 2007;86(6):75–80. (In Russ).</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Wiciński M, Sawicka E, Gębalski J, et al. Human Milk Oligosaccharides: Health Benefits, Potential Applications in Infant Formulas, and Pharmacology. Nutrients. 2020;12(1):266. doi: https://doi.org/10.3390/nu12010266</mixed-citation><mixed-citation xml:lang="en">Wiciński M, Sawicka E, Gębalski J, et al. Human Milk Oligosaccharides: Health Benefits, Potential Applications in Infant Formulas, and Pharmacology. Nutrients. 2020;12(1):266. doi: https://doi.org/10.3390/nu12010266</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Dinleyici M, Barbieur J, Dinleyici EC, Vandenplas Y. Functional effects of human milk oligosaccharides (HMOs). Gut Microbes. 2023;15(1):2186115. doi: https://doi.org/10.1080/19490976.2023.2186115</mixed-citation><mixed-citation xml:lang="en">Dinleyici M, Barbieur J, Dinleyici EC, Vandenplas Y. Functional effects of human milk oligosaccharides (HMOs). Gut Microbes. 2023;15(1):2186115. doi: https://doi.org/10.1080/19490976.2023.2186115</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Ben XM, Li J, Feng ZT, et al. Low level of galacto-oligosaccharide in infant formula stimulates growth of intestinal Bifidobacteria and Lactobacilli. World J Gastroenterol. 2008;14(42):6564–6568. doi: https://doi.org/10.3748/wjg.14.6564</mixed-citation><mixed-citation xml:lang="en">Ben XM, Li J, Feng ZT, et al. Low level of galacto-oligosaccharide in infant formula stimulates growth of intestinal Bifidobacteria and Lactobacilli. World J Gastroenterol. 2008;14(42):6564–6568. doi: https://doi.org/10.3748/wjg.14.6564</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Санникова Н.Е., Бородулина Т.В., Тиунова Е.Ю. и др. Роль функциональных компонентов адаптированных молочных смесей в коррекции нарушений пищеварительного тракта у детей, рожденных путем кесарева сечения // Лечащий Врач. — 2016. — № 11. — С. 1–4.</mixed-citation><mixed-citation xml:lang="en">Sannikova NE, Borodulina TV, Tiunova EYu, et al. Role of functional components of adapted milk mixtures in correction of gastrointestinal disorders in children born through cesarean section. Lechaschy Vrach. 2016;(11):1–4. (In Russ).</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Lemale J, Decline JL, Dive-Pouletty C, et al. Managing Cow’s Milk Protein Allergy with an Extensively Hydrolyzed Formula: Results from a Prospective, Non-Interventional Study in France (EVA Study). Nutrients. 2022;14(6):1203. doi: https://doi.org/10.3390/nu14061203</mixed-citation><mixed-citation xml:lang="en">Lemale J, Decline JL, Dive-Pouletty C, et al. Managing Cow’s Milk Protein Allergy with an Extensively Hydrolyzed Formula: Results from a Prospective, Non-Interventional Study in France (EVA Study). Nutrients. 2022;14(6):1203. doi: https://doi.org/10.3390/nu14061203</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Schoemaker AA, Sprikkelman AB, Grimshaw KE, et al. Incidence and natural history of challenge-proven cow’s milk allergy in European children — EuroPrevall birth cohort. Allergy. 2015;70(8):963–972. doi: https://doi.org/10.1111/all.12630</mixed-citation><mixed-citation xml:lang="en">Schoemaker AA, Sprikkelman AB, Grimshaw KE, et al. Incidence and natural history of challenge-proven cow’s milk allergy in European children — EuroPrevall birth cohort. Allergy. 2015;70(8):963–972. doi: https://doi.org/10.1111/all.12630</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Gupta RS, Springston EE, Warrier MR, et al. The prevalence, severity, and distribution of childhood food allergy in the United States. Pediatrics. 2011;128(1):e9–e17. doi: https://doi.org/10.1542/peds.2011-0204</mixed-citation><mixed-citation xml:lang="en">Gupta RS, Springston EE, Warrier MR, et al. The prevalence, severity, and distribution of childhood food allergy in the United States. Pediatrics. 2011;128(1):e9–e17. doi: https://doi.org/10.1542/peds.2011-0204</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Embleton ND, Jennifer Moltu S, Lapillonne A, et al. Enteral Nutrition in Preterm Infants (2022): A Position Paper From the ESPGHAN Committee on Nutrition and Invited Experts. J Pediatr Gastroenterol Nutr. 2023;76(2):248–268. doi: https://doi.org/10.1097/MPG.0000000000003642</mixed-citation><mixed-citation xml:lang="en">Embleton ND, Jennifer Moltu S, Lapillonne A, et al. Enteral Nutrition in Preterm Infants (2022): A Position Paper From the ESPGHAN Committee on Nutrition and Invited Experts. J Pediatr Gastroenterol Nutr. 2023;76(2):248–268. doi: https://doi.org/10.1097/MPG.0000000000003642</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Филатова Т.А., Лаврова Т.Е. Многообразие клинических проявлений аллергии к белкам коровьего молока у детей раннего возраста и современные возможности диетотерапии // Российский вестник перинатологии и педиатрии. — 2011. — № 3. — С. 88–92.</mixed-citation><mixed-citation xml:lang="en">Filatova TA, Lavrova TE. A diversity of the clinical manifestations of cow’s milk protein allergy in infants and the current possibilities of diet therapy. Rossiyskiy Vestnik Perinatologii i Pediatrii = Russian Bulletin of Perinatology and Pediatrics. 2011;(3):88–92. (In Russ).</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Баранов А.А., Намазова-Баранова Л.С., Хаитов Р.М. и др. Современные принципы ведение детей с пищевой аллергией // Педиатрическая фармакология. — 2021. — Т. 18. — № 3. — С. 245–263. — doi: https://doi.org/10.15690/pf.v18i1.2286</mixed-citation><mixed-citation xml:lang="en">Baranov AA, Namazova-Baranova LS, Khaitov RM, et al. Modern Principles of Managing Children with Food Allergies. Pediatricheskaya farmakologiya — Pediatric pharmacology. 2021;18(3):245–263. (In Russ). doi: https://doi.org/10.15690/pf.v18i3.2286</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Cuomo B, Indirli GC, Bianchi A, et al. Specific IgE and skin prick tests to diagnose allergy to fresh and baked cow’s milk according to age: a systematic review. Ital J Pediatr. 2017;43(1):93. doi: https://doi.org/10.1186/s13052-017-0410-8</mixed-citation><mixed-citation xml:lang="en">Cuomo B, Indirli GC, Bianchi A, et al. Specific IgE and skin prick tests to diagnose allergy to fresh and baked cow’s milk according to age: a systematic review. Ital J Pediatr. 2017;43(1):93. doi: https://doi.org/10.1186/s13052-017-0410-8</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Приходченко Н.Г., Шуматова Т.А., Катенкова Э.Ю., Коваленко Д.В. Клинические фенотипы пищевой аллергии к коровьему молоку у детей в зависимости от молекулярного профиля сенсибилизации // Аллергология и иммунология в педиатрии. — 2023. — № 2. — С. 13–18. — doi: https://doi.org/10.53529/2500-1175-2022-2-13-18</mixed-citation><mixed-citation xml:lang="en">Prihodchenko NG, Shumatova TA, Katenkova EYu, Kovalenko DV. Clinical phenotypes of cow’s milk food allergy in children depending on the molecular profile of sensitization. Allergology and Immunology in Pediatrics. 2022;(2):13–18. (In Russ). doi: https://doi.org/10.53529/2500-1175-2022-2-13-18</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Намазова-Баранова Л.С., Боровик Т.Э., Макарова С.Г. Аллергия на белок коровьего молока: тактика ведения больных на разных этапах диетотерапии // Педиатрия. Журнал им. Г.Н. Сперанского. — 2013. — Т. 92. — № 6. — С. 68–77.</mixed-citation><mixed-citation xml:lang="en">Namazova-Baranova LS, Borovik TE, Makarova SG. Allergiya na belok korov’ego moloka: taktika vedeniya bol’nykh na raznykh etapakh dietoterapii. Pediatria. Journal n.a. G.N. Speransky. 2013;92(6):68–77. (In Russ).</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Намазова-Баранова Л.С., Вишнева Е.А., Чемакина Д.С. и др. Современные методы диетотерапии аллергии к белкам коровьего молока у детей раннего возраста // Педиатрическая фармакология. — 2021. — Т. 18. — № 3. — С. 233–238. — doi: https://doi.org/10.15690/pf.v18i3.2283</mixed-citation><mixed-citation xml:lang="en">NamazovaBaranova LS, Vishneva EA, Chemakina DS, et al. Current Methods of Dietotherapy of Cow’s Milk Protein Allergy in Infants. Pediatricheskaya farmakologiya — Pediatric pharmacology. 2021;18(3):233–238. (In Russ). doi: https://doi.org/10.15690/pf.v18i3.2283</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Fewtrell M, Bronsky J, Campoy C, et al. Complementary Feeding: A Position Paper by the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) Committee on Nutrition. J Pediatr Gastroenterol Nutr. 2017;64(1):119–132. doi: https://doi.org/10.1097/MPG.0000000000001454</mixed-citation><mixed-citation xml:lang="en">Fewtrell M, Bronsky J, Campoy C, et al. Complementary Feeding: A Position Paper by the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) Committee on Nutrition. J Pediatr Gastroenterol Nutr. 2017;64(1):119–132. doi: https://doi.org/10.1097/MPG.0000000000001454</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Macchiaverni P, Rekima A, van den Elsen L, et al. Allergen shedding in human milk: Could it be key for immune system education and allergy prevention? J Allergy Clin Immunol. 2021;148(3):679– 688. doi: https://doi.org/10.1016/j.jaci.2021.07.012</mixed-citation><mixed-citation xml:lang="en">Macchiaverni P, Rekima A, van den Elsen L, et al. Allergen shedding in human milk: Could it be key for immune system education and allergy prevention? J Allergy Clin Immunol. 2021;148(3):679– 688. doi: https://doi.org/10.1016/j.jaci.2021.07.012</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Kramer MS, Kakuma R. Maternal dietary antigen avoidance during pregnancy or lactation, or both, for preventing or treating atopic disease in the child. Cochrane Database Syst Rev. 2012;2012(9):CD000133. doi: https://doi.org/10.1002/14651858.CD000133.pub3</mixed-citation><mixed-citation xml:lang="en">Kramer MS, Kakuma R. Maternal dietary antigen avoidance during pregnancy or lactation, or both, for preventing or treating atopic disease in the child. Cochrane Database Syst Rev. 2012;2012(9):CD000133. doi: https://doi.org/10.1002/14651858.CD000133.pub3</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Vandenplas Y, Brough H.A, Fiocchi A, et al. Current Guidelines and Future Strategies for the Management of Cow’s Milk Allergy. J Asthma Allergy. 2021;14:1243–1256. doi: https://doi.org/10.2147/JAA.S276992</mixed-citation><mixed-citation xml:lang="en">Vandenplas Y, Brough H.A, Fiocchi A, et al. Current Guidelines and Future Strategies for the Management of Cow’s Milk Allergy. J Asthma Allergy. 2021;14:1243–1256. doi: https://doi.org/10.2147/JAA.S276992</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Toca MC, Morais MB, Vázquez-Frias R, et al. Consensus on the diagnosis and treatment of cow’s milk protein allergy of the Latin American Society for Pediatric Gastroenterology, Hepatology and Nutrition. Rev Gastroenterol México Engl Ed. 2022;87(2):235–250. doi: https://doi.org/10.1016/j.rgmxen.2022.01.002</mixed-citation><mixed-citation xml:lang="en">Toca MC, Morais MB, Vázquez-Frias R, et al. Consensus on the diagnosis and treatment of cow’s milk protein allergy of the Latin American Society for Pediatric Gastroenterology, Hepatology and Nutrition. Rev Gastroenterol México Engl Ed. 2022;87(2):235–250. doi: https://doi.org/10.1016/j.rgmxen.2022.01.002</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Намазова-Баранова Л.С., Макарова С.Г., Новик Г.А., Вишнева Е.А. Диагностика и выбор лечебной смеси при аллергии к белкам коровьего молока. Обзор клинических рекомендаций // Доктор.Ру. — 2017. — № 4. — С. 61–68.</mixed-citation><mixed-citation xml:lang="en">NamazovaBaranova LS, Makarova SG, Novik GA, Vishneva EA. Cow’s Milk Protein Allergy: Diagnosis and Choice of Formula. Review of Clinical Guidelines. Doctor.Ru. 2017;(4):61–68. (In Russ).</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Rapp M, Martin-Paschoud C, Nutten S, et al. Characterization of an extensively hydrolyzed whey infant formula with a low bitterness. Clin Transl Allergy. 2013;3(Suppl 3):P132. doi: https://doi.org/10.1186/2045-7022-3-S3-P132</mixed-citation><mixed-citation xml:lang="en">Rapp M, Martin-Paschoud C, Nutten S, et al. Characterization of an extensively hydrolyzed whey infant formula with a low bitterness. Clin Transl Allergy. 2013;3(Suppl 3):P132. doi: https://doi.org/10.1186/2045-7022-3-S3-P132</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Nutten S, Maynard F, Järvi A, et al. Peptide size profile and residual immunogenic milk protein or peptide content in extensively hydrolyzed infant formulas. Allergy. 2020;75(6):1446–1449. doi: https://doi.org/10.1111/all.14098</mixed-citation><mixed-citation xml:lang="en">Nutten S, Maynard F, Järvi A, et al. Peptide size profile and residual immunogenic milk protein or peptide content in extensively hydrolyzed infant formulas. Allergy. 2020;75(6):1446–1449. doi: https://doi.org/10.1111/all.14098</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Баранов А.А., Намазова-Баранова Л.С., Алексеева А.А. и др. Применение у детей смесей на основе частично гидролизованного белка: методические рекомендации для педиатров. — М.: ПедиатрЪ; 2023. — 88 с.</mixed-citation><mixed-citation xml:lang="en">Baranov AA, Namazova-Baranova LS, Alekseeva AA, et al. Primenenie u detei smesei na osnove chastichno gidrolizovannogo belka: Guidelines for pediatricians. Moscow: Pediatr; 2023. 88 p. (In Russ).</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Nowak-Wegrzyn A, Czerkies L, Reyes K, et al. Confirmed Hypoallergenicity of a Novel Whey-Based Extensively Hydrolyzed Infant Formula Containing Two Human Milk Oligosaccharides. Nutrients. 2019;11(7):1447. doi: https://doi.org/10.3390/nu11071447</mixed-citation><mixed-citation xml:lang="en">Nowak-Wegrzyn A, Czerkies L, Reyes K, et al. Confirmed Hypoallergenicity of a Novel Whey-Based Extensively Hydrolyzed Infant Formula Containing Two Human Milk Oligosaccharides. Nutrients. 2019;11(7):1447. doi: https://doi.org/10.3390/nu11071447</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Jeffreys S. Human Milk Oligosaccharides: New Ways to Shape the Gut Microbiome in Cow’s Milk Protein Allergy. EMJ Allergy Immunol. 2019;4.1:48–54. doi: https://doi.org/10.33590/emjallergyimmunol/10311328</mixed-citation><mixed-citation xml:lang="en">Jeffreys S. Human Milk Oligosaccharides: New Ways to Shape the Gut Microbiome in Cow’s Milk Protein Allergy. EMJ Allergy Immunol. 2019;4.1:48–54. doi: https://doi.org/10.33590/emjallergyimmunol/10311328</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Vandenplas Y, Żołnowska M, Berni Canani R, et al. Effects of an Extensively Hydrolyzed Formula Supplemented with Two Human Milk Oligosaccharides on Growth, Tolerability, Safety and Infection Risk in Infants with Cow’s Milk Protein Allergy: A Randomized, Multi-Center Trial. Nutrients. 2022;14(3):530. doi: https://doi.org/10.3390/nu14030530</mixed-citation><mixed-citation xml:lang="en">Vandenplas Y, Żołnowska M, Berni Canani R, et al. Effects of an Extensively Hydrolyzed Formula Supplemented with Two Human Milk Oligosaccharides on Growth, Tolerability, Safety and Infection Risk in Infants with Cow’s Milk Protein Allergy: A Randomized, Multi-Center Trial. Nutrients. 2022;14(3):530. doi: https://doi.org/10.3390/nu14030530</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Berger B, Porta N, Foata F, et al. Linking Human Milk Oligosaccharides, Infant Fecal Community Types, and Later Risk To Require Antibiotics. Pettigrew MM, ed. mBio. 2020;11(2):e03196- 19. doi: https://doi.org/10.1128/mBio.03196-19</mixed-citation><mixed-citation xml:lang="en">Berger B, Porta N, Foata F, et al. Linking Human Milk Oligosaccharides, Infant Fecal Community Types, and Later Risk To Require Antibiotics. Pettigrew MM, ed. mBio. 2020;11(2):e03196- 19. doi: https://doi.org/10.1128/mBio.03196-19</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Vandenplas Y, Broekaert I, Domellöf M, et al. An ESPGHAN Position Paper on the Diagnosis, Management, and Prevention of Cow’s Milk Allergy. J Pediatr Gastroenterol Nutr. 2024;78(2):386– 413. doi: https://doi.org/10.1097/MPG.0000000000003897</mixed-citation><mixed-citation xml:lang="en">Vandenplas Y, Broekaert I, Domellöf M, et al. An ESPGHAN Position Paper on the Diagnosis, Management, and Prevention of Cow’s Milk Allergy. J Pediatr Gastroenterol Nutr. 2024;78(2):386– 413. doi: https://doi.org/10.1097/MPG.0000000000003897</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Cohen JT, Bellinger DC, Connor WE, Shaywitz BA. A quantitative analysis of prenatal intake of n-3 polyunsaturated fatty acids and cognitive development. Am J Prev Med. 2005;29(4):366–374. doi: https://doi.org/10.1016/j.amepre.2005.06.008</mixed-citation><mixed-citation xml:lang="en">Cohen JT, Bellinger DC, Connor WE, Shaywitz BA. A quantitative analysis of prenatal intake of n-3 polyunsaturated fatty acids and cognitive development. Am J Prev Med. 2005;29(4):366–374. doi: https://doi.org/10.1016/j.amepre.2005.06.008</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Hodgkinson A, Wall C, Wang W, et al. Nucleotides: an updated review of their concentration in breast milk. Nutr Res. 2022;99:13– 24. doi: https://doi.org/10.1016/j.nutres.2021.09.004</mixed-citation><mixed-citation xml:lang="en">Hodgkinson A, Wall C, Wang W, et al. Nucleotides: an updated review of their concentration in breast milk. Nutr Res. 2022;99:13– 24. doi: https://doi.org/10.1016/j.nutres.2021.09.004</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Walker-Smith JA, Digeon B, Phillips AD. Evaluation of a casein and a whey hydrolysate for treatment of cow’s-milk-sensitive enteropathy. Eur J Pediatr. 1989;149(1):68–71. doi: https://doi.org/10.1007/BF02024340</mixed-citation><mixed-citation xml:lang="en">Walker-Smith JA, Digeon B, Phillips AD. Evaluation of a casein and a whey hydrolysate for treatment of cow’s-milk-sensitive enteropathy. Eur J Pediatr. 1989;149(1):68–71. doi: https://doi.org/10.1007/BF02024340</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Walker-Smith JA. Cow milk-sensitive enteropathy: Predisposing factors and treatment. J Pediatr. 1992;121(5 Pt 2):S111–S115. doi: https://doi.org/10.1016/s0022-3476(05)81418-0</mixed-citation><mixed-citation xml:lang="en">Walker-Smith JA. Cow milk-sensitive enteropathy: Predisposing factors and treatment. J Pediatr. 1992;121(5 Pt 2):S111–S115. doi: https://doi.org/10.1016/s0022-3476(05)81418-0</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Методическое руководство по применению аминокислотных смесей / под ред. Л.С. Намазовой-Барановой; Союз педиатров России. — 2-е изд. — М.: ПедиатрЪ; 2021. — 104 с.</mixed-citation><mixed-citation xml:lang="en">Metodicheskoe rukovodstvo po primeneniyu aminokislotnykh smesei. Namazova-Baranova LS, ed.; Union of Pediatricians of Russia. 2nd edn. Moscow: Pediatr; 2021. 104 p. (In Russ).</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">Latcham F, Merino F, Lang A, et al. A consistent pattern of minor immunodeficiency and subtle enteropathy in children with multiple food allergy. J Pediatr. 2003;143(1):39–47. doi: https://doi.org/10.1016/S0022-3476(03)00193-8</mixed-citation><mixed-citation xml:lang="en">Latcham F, Merino F, Lang A, et al. A consistent pattern of minor immunodeficiency and subtle enteropathy in children with multiple food allergy. J Pediatr. 2003;143(1):39–47. doi: https://doi.org/10.1016/S0022-3476(03)00193-8</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Vanderhoof J, Moore N, De Boissieu D. Evaluation of an Amino Acid-Based Formula in Infants Not Responding to Extensively Hydrolyzed Protein Formula. J Pediatr Gastroenterol Nutr. 2016;63(5):531– 533. doi: https://doi.org/10.1097/MPG.0000000000001374</mixed-citation><mixed-citation xml:lang="en">Vanderhoof J, Moore N, De Boissieu D. Evaluation of an Amino AcidBased Formula in Infants Not Responding to Extensively Hydrolyzed Protein Formula. J Pediatr Gastroenterol Nutr. 2016;63(5):531– 533. doi: https://doi.org/10.1097/MPG.0000000000001374</mixed-citation></citation-alternatives></ref><ref id="cit63"><label>63</label><citation-alternatives><mixed-citation xml:lang="ru">Corkins M, Czerkies LA, Storm HM, et al. Assessment of Growth of Infants Fed an Amino Acid-Based Formula. Clin Med Insights Pediatr. 2016;10:3–9. doi: https://doi.org/10.4137/CMPed.S33071</mixed-citation><mixed-citation xml:lang="en">Corkins M, Czerkies LA, Storm HM, et al. Assessment of Growth of Infants Fed an Amino Acid-Based Formula. Clin Med Insights Pediatr. 2016;10:3–9. doi: https://doi.org/10.4137/CMPed.S33071</mixed-citation></citation-alternatives></ref><ref id="cit64"><label>64</label><citation-alternatives><mixed-citation xml:lang="ru">Gold MS, Quinn PJ, Campbell DE, et al. Effects of an Amino Acid-Based Formula Supplemented with Two Human Milk Oligosaccharides on Growth, Tolerability, Safety, and Gut Microbiome in Infants with Cow’s Milk Protein Allergy. Nutrients. 2022;14(11):2297. doi: https://doi.org/10.3390/nu14112297</mixed-citation><mixed-citation xml:lang="en">Gold MS, Quinn PJ, Campbell DE, et al. Effects of an Amino AcidBased Formula Supplemented with Two Human Milk Oligosaccharides on Growth, Tolerability, Safety, and Gut Microbiome in Infants with Cow’s Milk Protein Allergy. Nutrients. 2022;14(11):2297. doi: https://doi.org/10.3390/nu14112297</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
