ppharmПедиатрическая фармакологияPediatric pharmacology1727-57762500-3089Издательство «ПедиатрЪ»10.15690/pf.v10i1.586ppharm-250Research ArticleЛЕКЦИЯLECTUREПРИМЕНЕНИЕ ВНУТРИВЕННЫХ ИММУНОГЛОБУЛИНОВ В КЛИНИЧЕСКОЙ ПРАКТИКЕINTRAVENOUS IMMUNOGLOBULIN APPLICATION IN CLINICAL PRACTICEЛатышеваТ. В.LatyshevaT. V.

профессор, доктор наук, заведующая отделением иммунопатологии взрослых и отделением реанимации иинтенсивной терапии ФГБУ «ГНЦ Институт иммунологии» ФМБА России

tvlat@mail.ruЛатышеваЕ. А.LatyshevaE. A.Государственный научный центр «Институт иммунологии» Федерального медико-биологического агентства России, Москва, Российская ФедерацияРоссияState Scientific Center «Immunology Institute» of the Federal Medical Biological Agency of Russia, Moscow, Russian FederationRussian Federation201313022013101Педиатрическая фармакология2630Copyright © Латышева Т.В., Латышева Е.А., 20132013Латышева Т.В., Латышева Е.А.Latysheva T.V., Latysheva E.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.pedpharma.ru/jour/article/view/250

В статье представлены данные о структуре и функции иммуноглобулинов. Учитывая многообразие механизмов их действия, показания к их применению постоянно расширяются. В настоящее время иммуноглобулины применяются в качестве заместительной и иммуномодулирующей терапии разнонаправленного действия (стимуляция/супрессия). На основании данных литературы освещены механизмы действия и точки приложения иммуноглобулинов для внутривенного введения в клинической практике. Показаны преимущества отечественного препарата для внутривенного введения.

The article gives data on the structure and function of immunoglobulins. Given the multitude of mechanisms of their action, indications to their use are constantly expanding. At present, immunoglobulins are used as replacement and immunomodulatory therapy of multidirectional action (stimulation/suppression). Mechanisms of action and points of immunoglobulin intravenous application in clinical practice are covered on the basis of literary data. Advantages of the domestic drug for intravenous application are shown.

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The authors declare that there are no conflicts of interest present.