ppharmПедиатрическая фармакологияPediatric pharmacology1727-57762500-3089Издательство «ПедиатрЪ»10.15690/pf.v21i3.2757ppharm-2463Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEWКогнитивные, эмоциональные и поведенческие нарушения у детей с респираторными аллергическими заболеваниями: причины и пути решенияCognitive, Emotional, and Behavioral Disorders in Children with Respiratory Allergic Diseases: Causes and Solutionshttps://orcid.org/0000-0002-3167-082XУстиноваН. В.UstinovaNatalia V.

Устинова Наталия Вячеславовна - доктор медицинских наук, заведующая отделом социальной педиатрии и организации мультидисциплинарного сопровождения.

119333, Москва, ул. Фотиевой, д. 10, стр. 1, тел.: +7 (499) 137-01-97

MD, PhD.

10, Fotievoi Str., building 1, Moscow, 119333

dr.natustinova@gmail.comhttps://orcid.org/0000-0002-8540-3858КаркашадзеГ. А.KarkashadzeGeorge A.

Каркашадзе Георгий Арчилович - к.м.н.

Москва

MD, PhD.

Moscow

karkaga@mail.ruhttps://orcid.org/0000-0002-2209-7531Намазова-БарановаЛ. С.Namazova-BaranovaLeyla S.

Намазова-Баранова Лейла Сеймуровна - д.м.н., профессор, академик РАН.

Москва

MD, PhD, Professor, Academician of the RAS.

Moscow

leyla.s.namazova@gmail.comНИИ педиатрии и охраны здоровья детей НКЦ №2 ФГБНУ «РНЦХ им. акад. Б.В. Петровского»; НПЦ психического здоровья детей и подростков им. Г.Е. СухаревойРоссияResearch Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of Surgery; G.E. Sukhareva Scientific-practical Children’s and Adolescents Mental Health Center, Scientific-practical Children’s and Adolescents Mental Health CenterRussian FederationНИИ педиатрии и охраны здоровья детей НКЦ №2 ФГБНУ «РНЦХ им. акад. Б.В. Петровского»РоссияResearch Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of SurgeryRussian FederationНИИ педиатрии и охраны здоровья детей НКЦ №2 ФГБНУ «РНЦХ им. акад. Б.В. Петровского»; РНИМУ им. Н.И. ПироговаРоссияResearch Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of Surgery; Pirogov Russian National Research Medical UniversityRussian Federation202403072024213226239Copyright © Устинова Н.В., Каркашадзе Г.А., Намазова-Баранова Л.С., 20242024Устинова Н.В., Каркашадзе Г.А., Намазова-Баранова Л.С.Ustinova N.V., Karkashadze G.A., Namazova-Baranova L.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.pedpharma.ru/jour/article/view/2463

Публикация посвящена обзору накопившихся данных о связи респираторной аллергопатологии с нейропсихическими расстройствами в детском возрасте. Актуальность проблемы обусловлена взаимовлиянием сочетающихся у ребенка аллергических и нейропсихических состояний на течение этих заболеваний. Согласно исследованиям, отчетливо проявляется связь респираторных аллергических заболеваний с нарушениями нейроразвития, в частности с синдромом дефицита внимания и гиперактивности и расстройствами аутистического спектра, появились и первые публикации о связи с речевыми и другими нетяжелыми когнитивными нарушениями. Одновременно активно изучается формирование при респираторной аллергопатологии депрессий, суицидального поведения, тревожных расстройств. Предполагается, что тесная взаимосвязь нервной и иммунной регуляций обеспечивает высокую сопряженность аллергических и нейропсихических патологических состояний, хотя причинно-следственные связи пока точно не установлены. В связи с этим становится актуальным внедрение в клиническую практику мониторинга когнитивного статуса, нейропсихического развития и возможных симптомов тревоги, депрессии и суицидальных мыслей при терапии детей с респираторными аллергическими заболеваниями. Вовремя выявленные нарушения позволят на раннем этапе оказывать специализированные вмешательства с целью достижения благоприятного результата лечения в долгосрочной перспективе.

The publication is devoted to the review of accumulated data on the relationship of respiratory allergopathology with neuropsychiatric disorders in childhood. The immediacy of the problem is due to the mutual influence of allergic and neuropsychiatric conditions combined in a child on the course of these diseases. According to research, the connection of respiratory allergic diseases with disorders of neurodevelopment, in particular with attention deficit and hyperactivity disorder and autism spectrum disorders, is clearly manifested, and the first publications on the connection with speech and other mild cognitive impairments have appeared. At the same time, the formation of depression, suicidal behavior, and anxiety disorders in respiratory allergopathology is being actively studied. It is assumed that the close relationship between nervous and immune regulation provides a high correlation of allergic and neuropsychiatric pathological conditions, although cause-and-effect relationships have not yet been precisely established. In this regard, it becomes relevant to introduce into clinical practice monitoring of cognitive status, neuropsychic development and possible symptoms of anxiety, depression and suicidal thoughts in the treatment of children with respiratory allergic diseases. Timely detection of violations will make it possible to provide specialized interventions at an early stage in order to achieve a favorable treatment result in the long term.

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The authors declare that there are no conflicts of interest present.