Attention to the issue of realizing and appreciating pain by children has been increasing within the last 20 years. Papillomavirus skin infection is a widespread dermatosis in younger children. The only treatment method is mechanical removal, which is accompanied by pain, while cosmetic defect caused by verruciform outgrowths on skin, especially in facial and hand areas, causes psychological problems leading to the child’s life quality reduction. The following study assessed efficacy of local analgesic when removing flat warts and papillomata. The obtained results indicate that the use of anesthetic plaster with 5% lidocaine reduces both pain intensity and psychological distress. Plaster therapeutic system is a highly effective analgesic for application anesthesia used to conduct course injections, venous blood sampling and vaccination. This remedy is also recommended for anaesthetization of skin when conducting dermatologic procedures. Convenience and simplicity of use allow using it not only in clinical conditions, but also domiciliary, in particular, by patients themselves.