ppharmПедиатрическая фармакологияPediatric pharmacology1727-57762500-3089Издательство «ПедиатрЪ»10.15690/pf.v10i3.694ppharm-216Research ArticleНЕОТЛОЖНЫЕ СОСТОЯНИЯ У ДЕТЕЙEMERGENCY CONDITIONS IN CHILDRENОСЛОЖНЕНИЯ ПАРЕНТЕРАЛЬНОГО ПИТАНИЯ В ПЕДИАТРИИPARENTERAL FEEDING COMPLICATIONS IN PEDIATRICSТепаевР. Ф.TepaevR. F.

доктор медицинских наук, заведующий отделением реанимации и интенсивной терапии с группой реанимации и интенсивной терапии новорожденных и недоношенных детей ФГБУ «Научный центр здоровья детей» РАМН, профессор кафедры педиатрии с курсом детской ревматологии Московского государственного медицинского университета имени И.М. Сеченова

PhD, head of the resuscitation and intensive therapy department with a resuscitation and intensive therapy group for newborn and premature infants at the FSBI “Scientific Center of Children’s Health”, professor of the pediatrics department with pediatric rheumatology course at Sechenov First Moscow State Medical University

rtepaev@inbox.ruКирьяноваА. Н.KiryanovaA. N.БелоусоваА. С.BelousovaA. S.ИльичёваЕ. И.IlyichyovaE. I.ЛазареваА. В.LazarevaA. V.КрыжановскаяО. А.KryzhanovskayaO. A.Научный центр здоровья детей РАМН, Москва, Российская Федерация Первый Московский государственный медицинский университет им. И.М. Сеченова, Российская ФедерацияРоссияScientific Center of Children’s Health Moscow, Russian Federation The First Sechenov Moscow State Medical University, Russian FederationRussian FederationНаучный центр здоровья детей РАМН, Москва, Российская ФедерацияRussian FederationScientific Center of Children’s Health Moscow, Russian FederationRussian Federation201303062013103Педиатрическая фармакология2631Copyright © Тепаев Р.Ф., Кирьянова А.Н., Белоусова А.С., Ильичёва Е.И., Лазарева А.В., Крыжановская О.А., 20132013Тепаев Р.Ф., Кирьянова А.Н., Белоусова А.С., Ильичёва Е.И., Лазарева А.В., Крыжановская О.А.Tepaev R.F., Kiryanova A.N., Belousova A.S., Ilyichyova E.I., Lazareva A.V., Kryzhanovskaya O.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.pedpharma.ru/jour/article/view/216

The article is dedicated to parenteral feeding – infusion therapy aimed at introducing water, macro- and micronutrients in concordance with body needs. Different parenteral feeding types are described: complete, partial and additional. It shows that balanced parenteral feeding allows providing the child’s body with the sufficient amount of amino acids, carbohydrates, fats and energy required to maintain a baseline energy level and correct a preceding nutritive insufficiency. Protein-energy homeostasis is the basis for vital activity of the body; it determines the inflammatory response activity, immune status adequacy, disease duration and severity and disease prognosis (to a considerable degree). Long-term parenteral feeding is associated with complications of varying severity: from transitory and mild to severe, requiring operative intervention and liver transplantation. The command of modern recommendations allows a practicing doctor to successfully overcome issues associated with long-term parenteral feeding. The article presents modern data on diagnostics, prevention and treatment of parenteral feeding complications.

парентеральное питаниеосложнениядетиинфузионная терапиянутриентыparenteral feedingcomplicationschildreninfusion therapynutrientsReferencesТепаев Р. Ф., Александров А. Е., Киргизов И. В., Смирнова Т. Н., Рыбалко А. С. Парентеральное питание в педиатрии и детской хирургии. Педиатр. фармакол. 2012; 9 (1): 36–44.Tepaev R. F., Aleksandrov A. E., Kirgizov I. V., Smirnova T. N., Rybalko A. S. Parenteral feeding in pediatrics and pediatric surgery. Pediatr. farmakol. = Pediatric pharmacology. 2012; 9 (1): 36–44.Koletzko B., Agostoni C., Ball P., Carnielli V., Chaloner C., Clayton J., Colomb V. et al. ESPEN/ESPGHAN Guidelines on paediatric parenteral nutrition. Clin. Nutr. 2006; 25: 177–360.Koletzko B., Agostoni C., Ball P., Carnielli V., Chaloner C., Clayton J., Colomb V. et al. ESPEN/ESPGHAN Guidelines on paediatric parenteral nutrition. Clin. Nutr. 2006; 25: 177–360.Goldstein B., Giroir B., Randolph A. and the Members of the International Consensus Conference on Pediatric Sepsis. International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics. Pediatr. Crit. Care Med. 2005; 6: 2–8.Goldstein B., Giroir B., Randolph A. and the Members of the International Consensus Conference on Pediatric Sepsis. International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics. Pediatr. Crit. Care Med. 2005; 6: 2–8.Бережанский Б. В., Жевнерев А. А. Катетер-ассоциированные инфекции кровотока. Клин. микробиол. антимикроб. химиотер. 2006; 8 (2): 130–144.Berezhanskii B. V., Zhevnerev A. A. Catheter-related blood flow infections. Klin. mikrobiol. antimikrob. khimioter. = Clinical microbiology and antimicrobial chemotherapy. 2006; 8 (2): 130–144.Smith V. C., Hallett J. W. Subclavian vein thrombosis during prolonged catheterization for parenteral nutrition: early management and long-term follow-up. South Med. J. 1983; 76: 603–606.Smith V. C., Hallett J. W. Subclavian vein thrombosis during prolonged catheterization for parenteral nutrition: early management and long-term follow-up. South Med. J. 1983; 76: 603–606.Lumpkin M. M. Safety alert: hazards of precipitation associated with parenteral nutrition. Am. J. Hosp. Pharm. 1994; 51: 1427–1428.Lumpkin M. M. Safety alert: hazards of precipitation associated with parenteral nutrition. Am. J. Hosp. Pharm. 1994; 51: 1427–1428.URL: http://www.berlin-chemie.ru/info/texts/1-4-63.htmAvailable at: http://www.berlin-chemie.ru/info/texts/1-4-63.htmNorman K., Pichard C., Lochs H., Pirlich M. Prognostic impact of disease — related malnutrition. Clin. Nutr. 2008; 27: 5–15.Norman K., Pichard C., Lochs H., Pirlich M. Prognostic impact of disease — related malnutrition. Clin. Nutr. 2008; 27: 5–15.Elia M. Changing concepts of nutrient requirements in disease: implications for artificial nutritional support. Lancet. 1995; 345: 1279–1284.Elia M. Changing concepts of nutrient requirements in disease: implications for artificial nutritional support. Lancet. 1995; 345: 1279–1284.Dellert S. F., Farrell M. K., Specker B. L., Heubi J. E. Bone mineral content in children with short bowel syndrome after discontinuation of parental nutrition. J. Pediatr. 1998; 132: 516–519.Dellert S. F., Farrell M. K., Specker B. L., Heubi J. E. Bone mineral content in children with short bowel syndrome after discontinuation of parental nutrition. J. Pediatr. 1998; 132: 516–519.Fouin-Fortunet H., Le Quernec L., Erlinger S., Lerebours E., Colin R. Hepatic alterations during total parenteral nutrition in patients with inflammatory bowel disease: a possible consequence of lithocholate toxicity. Gastroenterology. 1982; 82: 932–937.Fouin-Fortunet H., Le Quernec L., Erlinger S., Lerebours E., Colin R. Hepatic alterations during total parenteral nutrition in patients with inflammatory bowel disease: a possible consequence of lithocholate toxicity. Gastroenterology. 1982; 82: 932–937.Moseley R. H. A molecular basis for jaundice in intrahepatic and extrahepatic cholestasis. Hepatology. 1997; 26: 1682–1684.Moseley R. H. A molecular basis for jaundice in intrahepatic and extrahepatic cholestasis. Hepatology. 1997; 26: 1682–1684.

The authors declare that there are no conflicts of interest present.