<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="editorial" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ppharm</journal-id><journal-title-group><journal-title xml:lang="ru">Педиатрическая фармакология</journal-title><trans-title-group xml:lang="en"><trans-title>Pediatric pharmacology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-5776</issn><issn pub-type="epub">2500-3089</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ppharm-212</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ВАКЦИНАЦИЯ В СОВРЕМЕННОМ МИРЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>VACCINATION</subject></subj-group></article-categories><title-group><article-title>РОТАВИРУСНЫЕ ВАКЦИНЫ ДОКУМЕНТ ПО ПОЗИЦИИ ВОЗ (ЯНВАРЬ 2013 Г.)</article-title><trans-title-group xml:lang="en"><trans-title>ROTAVIRUS VACCINES (WHO POSITION PAPER — JANUARY 2013)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Редакционная</surname><given-names>статья</given-names></name><name name-style="western" xml:lang="en"><surname>Editorial</surname><given-names>Article</given-names></name></name-alternatives><email xlink:type="simple">neonatepearl@yandex.ru</email></contrib></contrib-group><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>14</day><month>08</month><year>2013</year></pub-date><volume>10</volume><issue>4</issue><issue-title>Педиатрическая фармакология</issue-title><fpage>16</fpage><lpage>29</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Редакционная с., 2013</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="ru">Редакционная с.</copyright-holder><copyright-holder xml:lang="en">Editorial a.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pedpharma.ru/jour/article/view/212">https://www.pedpharma.ru/jour/article/view/212</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">See http://www.who.int/immunization/sage/en</mixed-citation><mixed-citation xml:lang="en">See http://www.who.int/immunization/sage/en</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Sanderson C. et al. Global review of rotavirus morbidity and mortality data by age and WHO region. Report to WHO/IVB, 2011 (www.who.int/entity/immunization/sage/meetings/2012/april/presentations_background_docs/en/ — 45k).</mixed-citation><mixed-citation xml:lang="en">Sanderson C. et al. Global review of rotavirus morbidity and mortality data by age and WHO region. Report to WHO/IVB, 2011 (www.who.int/entity/immunization/sage/meetings/2012/april/presentations_background_docs/en/ — 45k).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Detailed review paper on rotavirus vaccines (presented to the WHO Strategic Advisory Group of Experts (SAGE) on Immunization in April 2009). Geneva, World Health Organization. 2009. Available from (http://www.who.int/immunization/sage/3_Detailed_ Review_Paper_on_Rota_Vaccines_17_3_2009.pdf).</mixed-citation><mixed-citation xml:lang="en">Detailed review paper on rotavirus vaccines (presented to the WHO Strategic Advisory Group of Experts (SAGE) on Immunization in April 2009). Geneva, World Health Organization. 2009. Available from (http://www.who.int/immunization/sage/3_Detailed_ Review_Paper_on_Rota_Vaccines_17_3_2009.pdf).</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">WHO estimate for January 2012: http://www.who.int/immunization_monitoring/burden/rotavirus_estimates/en/index.html</mixed-citation><mixed-citation xml:lang="en">WHO estimate for January 2012: http://www.who.int/immunization_monitoring/burden/rotavirus_estimates/en/index.html</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Parashar D.U. et al. Global illness and deaths caused by rotavirus disease in children. Emerging Infectious Diseases, 2003, 9: 565–572.</mixed-citation><mixed-citation xml:lang="en">Parashar D.U. et al. Global illness and deaths caused by rotavirus disease in children. Emerging Infectious Diseases, 2003, 9: 565–572.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Weekly Epidemiological Record. 2008; 47: 421–425. URL: http://www.who.int/wer</mixed-citation><mixed-citation xml:lang="en">Weekly Epidemiological Record. 2008; 47: 421–425. URL: http://www.who.int/wer</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Hu L. et al. Rotavirus non-structural proteins: structure and function. Current Opinion in Virology. 2012, 2: 380–388.</mixed-citation><mixed-citation xml:lang="en">Hu L. et al. Rotavirus non-structural proteins: structure and function. Current Opinion in Virology. 2012, 2: 380–388.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Manual of rotavirus detection and characterization methods (WHO/IVB/08.17). Geneva, World Health Organization. 2009. Available from http://www.who.int/nuvi/rotavirus/WHO_IVB_08.17_eng.pdf, accessed January 2013.</mixed-citation><mixed-citation xml:lang="en">Manual of rotavirus detection and characterization methods (WHO/IVB/08.17). Geneva, World Health Organization. 2009. Available from http://www.who.int/nuvi/rotavirus/WHO_IVB_08.17_eng.pdf, accessed January 2013.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Gladstone B.P. et al. Protective effect of natural rotavirus infection in an Indian birth cohort. New England Journal of Medicine, 2011, 365: 337–346.</mixed-citation><mixed-citation xml:lang="en">Gladstone B.P. et al. Protective effect of natural rotavirus infection in an Indian birth cohort. New England Journal of Medicine, 2011, 365: 337–346.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Velazquez F.R., Matson D.O., Calva J.J. et al. Rotavirus infection in infants as protection against subsequent infections. New England Journal of Medicine, 1996, 335: 1022–1028.</mixed-citation><mixed-citation xml:lang="en">Velazquez F.R., Matson D.O., Calva J.J. et al. Rotavirus infection in infants as protection against subsequent infections. New England Journal of Medicine, 1996, 335: 1022–1028.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Oral rehydration salts. Production of the new ORS (WHO/FCH/CAH/06.1). Geneva, WHO/UNICEF. 2006. Available from http://whqlibdoc.who.int/hq/2006/WHO_FCH_CAH_06.1.pdf, accessed January 2013.</mixed-citation><mixed-citation xml:lang="en">Oral rehydration salts. Production of the new ORS (WHO/FCH/CAH/06.1). Geneva, WHO/UNICEF. 2006. Available from http://whqlibdoc.who.int/hq/2006/WHO_FCH_CAH_06.1.pdf, accessed January 2013.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Angel J. et al. Rotavirus immune responses and correlates of protection. Current Opinion in Virology. 2012. P. 419–425.</mixed-citation><mixed-citation xml:lang="en">Angel J. et al. Rotavirus immune responses and correlates of protection. Current Opinion in Virology. 2012. P. 419–425.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Clark H.F. et al. Rotavirus vaccines. In: Plotkin S., Orenstein W., Offit P., eds. Vaccines, 6 th ed. Elsevier Saunders. 2013. P. 669–687.</mixed-citation><mixed-citation xml:lang="en">Clark H.F. et al. Rotavirus vaccines. In: Plotkin S., Orenstein W., Offit P., eds. Vaccines, 6 th ed. Elsevier Saunders. 2013. P. 669–687.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Groome M.J. et al. Five-year cohort study on the burden of hospitalisation for acute diarrhoeal disease in African HIV-infected and HIV-uninfected children: potential benefits of rotavirus vaccine. Vaccine. 2012; 30 (Suppl. 1): A173–178.</mixed-citation><mixed-citation xml:lang="en">Groome M.J. et al. Five-year cohort study on the burden of hospitalisation for acute diarrhoeal disease in African HIV-infected and HIV-uninfected children: potential benefits of rotavirus vaccine. Vaccine. 2012; 30 (Suppl. 1): A173–178.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Cunliffe N.A. et al. Effect of concomitant HIV infection on presentation and outcome of rotavirus gastroenteritis in Malawian children. Lancet. 2001; 358 (9281): 550–555.</mixed-citation><mixed-citation xml:lang="en">Cunliffe N.A. et al. Effect of concomitant HIV infection on presentation and outcome of rotavirus gastroenteritis in Malawian children. Lancet. 2001; 358 (9281): 550–555.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Guidelines to assure the quality, safety and efficacy of live attenuated rotavirus vaccine Annex 3). Geneva, World Health Organization. 2007. WHO Technical report series 941.</mixed-citation><mixed-citation xml:lang="en">Guidelines to assure the quality, safety and efficacy of live attenuated rotavirus vaccine Annex 3). Geneva, World Health Organization. 2007. WHO Technical report series 941.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Available from http://www.who.int/entity/biologicals/publications/trs/areas/vaccines/rotavirus/Annex %203 %20rotavirus %20vaccines.pdf, accessed January 2013.</mixed-citation><mixed-citation xml:lang="en">Available from http://www.who.int/entity/biologicals/publications/trs/areas/vaccines/rotavirus/Annex %203 %20rotavirus %20vaccines.pdf, accessed January 2013.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">See http://www.who.int/entity/immunization_standards/vaccine_quality/Rotarix_ liquid_tube_product_insert_text_2009.pdf</mixed-citation><mixed-citation xml:lang="en">See http://www.who.int/entity/immunization_standards/vaccine_quality/Rotarix_ liquid_tube_product_insert_text_2009.pdf</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">See http://www.who.int/entity/immunization_standards/vaccine_quality/Rotarix liquid_oral_applicator_product_insert_text_2009.pdf</mixed-citation><mixed-citation xml:lang="en">See http://www.who.int/entity/immunization_standards/vaccine_quality/Rotarix liquid_oral_applicator_product_insert_text_2009.pdf</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">See http://www.who.int/entity/immunization_standards/vaccine_quality/RotaTeq_ Product_Insert.pdf and http://www.merck.com/product/usa/pi_circulars/r/rotateq/rotateq_pi.pdf</mixed-citation><mixed-citation xml:lang="en">See http://www.who.int/entity/immunization_standards/vaccine_quality/RotaTeq_ Product_Insert.pdf and http://www.merck.com/product/usa/pi_circulars/r/rotateq/rotateq_pi.pdf</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Soares-Weiser K. et al. Vaccines for preventing rotavirus diarrhoea: vaccines in use. Cochrane Database Systematic Review. 2012; 11: CD008521.</mixed-citation><mixed-citation xml:lang="en">Soares-Weiser K. et al. Vaccines for preventing rotavirus diarrhoea: vaccines in use. Cochrane Database Systematic Review. 2012; 11: CD008521.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">To aid in cause of death and burden of disease analyses, subregions are stratified (A through E) based on levels of child and adult mortality: Stratum A., very low child and very low adult mortality; Stratum B., low child and low adult mortality; Stratum C., low child and high adult mortality; Stratum D., high child and high adult mortality; Stratum E., high child and very high adult mortality. The 9 low- and middle-income subregions included in the model are:</mixed-citation><mixed-citation xml:lang="en">To aid in cause of death and burden of disease analyses, subregions are stratified (A through E) based on levels of child and adult mortality: Stratum A., very low child and very low adult mortality; Stratum B., low child and low adult mortality; Stratum C., low child and high adult mortality; Stratum D., high child and high adult mortality; Stratum E., high child and very high adult mortality. The 9 low- and middle-income subregions included in the model are:</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">African Region: D and E; Region of the Americas: B and D; South-East Asia Region: B and D, Eastern Mediterranean Region: B and D, and Western Pacific Region: B. Please consult the List of Member States by WHO region and mortality stratum available at www.who.int/entity/whr/2003/en/member_states_182–184_en.pdf,accessed January 2013.</mixed-citation><mixed-citation xml:lang="en">African Region: D and E; Region of the Americas: B and D; South-East Asia Region: B and D, Eastern Mediterranean Region: B and D, and Western Pacific Region: B. Please consult the List of Member States by WHO region and mortality stratum available at www.who.int/entity/whr/2003/en/member_states_182–184_en.pdf,accessed January 2013.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Grading of scientific evidence — Tables 1–4: Does RV1 and RV5 induce protection against rotavirus morbidity and mortality in young children both in low and high mortality settings? Available from http://www.who.int/immunization/position_papers/rotavirus_grad_rv1_rv5_protection</mixed-citation><mixed-citation xml:lang="en">Grading of scientific evidence — Tables 1–4: Does RV1 and RV5 induce protection against rotavirus morbidity and mortality in young children both in low and high mortality settings? Available from http://www.who.int/immunization/position_papers/rotavirus_grad_rv1_rv5_protection</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Patel M.M. et al. Removing the Age Restrictions for Rotavirus Vaccination: A Benefit-Risk Modeling Analysis. PLoS Medicine. 2012; 9: e1001330.</mixed-citation><mixed-citation xml:lang="en">Patel M.M. et al. Removing the Age Restrictions for Rotavirus Vaccination: A Benefit-Risk Modeling Analysis. PLoS Medicine. 2012; 9: e1001330.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Giaquinto C. et al. Summary of effectiveness and impact of rotavirus vaccination with the oral pentavalent rotavirus vaccine: a systematic review of the experience in industrialized countries. Human Vaccines. 2011; 7: 734–748.</mixed-citation><mixed-citation xml:lang="en">Giaquinto C. et al. Summary of effectiveness and impact of rotavirus vaccination with the oral pentavalent rotavirus vaccine: a systematic review of the experience in industrialized countries. Human Vaccines. 2011; 7: 734–748.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Richardson V. et al. Effect of rotavirus vaccination on death from childhood diarrhea in Mexico. New England Journal of Medicine. 2010; 362: 299–305.</mixed-citation><mixed-citation xml:lang="en">Richardson V. et al. Effect of rotavirus vaccination on death from childhood diarrhea in Mexico. New England Journal of Medicine. 2010; 362: 299–305.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">do Carmo G.M. et al. Decline in diarrhoea mortality and admissions after routine childhood rotavirus immunization in Brazil: a time-series analysis. PLoS Medicine. 2011; 8: e1001024</mixed-citation><mixed-citation xml:lang="en">do Carmo G.M. et al. Decline in diarrhoea mortality and admissions after routine childhood rotavirus immunization in Brazil: a time-series analysis. PLoS Medicine. 2011; 8: e1001024</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Wang F.T. et al. Effectiveness of an Incomplete RotaTeq® (RV5) Vaccination Regimen in Preventing Rotavirus Gastroenteritis in the United States. The Pediatric Infectious Disease Journal. 2012. [Epub ahead of print].</mixed-citation><mixed-citation xml:lang="en">Wang F.T. et al. Effectiveness of an Incomplete RotaTeq® (RV5) Vaccination Regimen in Preventing Rotavirus Gastroenteritis in the United States. The Pediatric Infectious Disease Journal. 2012. [Epub ahead of print].</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Vesikari T. et al. Safety and efficacy of pentavalent humanbovine (WC3) reassortant rotavirus vaccine in preventing rotavirus gastroenteritis and reducing associated health care resource utilization. The New England Journal of Medicine. 2006; 354: 23–33.</mixed-citation><mixed-citation xml:lang="en">Vesikari T. et al. Safety and efficacy of pentavalent humanbovine (WC3) reassortant rotavirus vaccine in preventing rotavirus gastroenteritis and reducing associated health care resource utilization. The New England Journal of Medicine. 2006; 354: 23–33.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Vesikari T. et al. Efficacy of the pentavalent rotavirus vaccine, RotaTeq®, in Finnish infants up to 3 years of age: the Finnish Extension Study. European Journal of Pediatrics. 2010; 169: 1379–1386.</mixed-citation><mixed-citation xml:lang="en">Vesikari T. et al. Efficacy of the pentavalent rotavirus vaccine, RotaTeq®, in Finnish infants up to 3 years of age: the Finnish Extension Study. European Journal of Pediatrics. 2010; 169: 1379–1386.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Linhares A.C. et al. Efficacy and safety of an oral live attenuated human rotavirus vaccine against rotavirus gastroenteritis during the first 2 years of life in Latin American infants: a randomised, double-blind, placebo-controlled phase III study. Lancet. 2008; 371: 1181–1189.</mixed-citation><mixed-citation xml:lang="en">Linhares A.C. et al. Efficacy and safety of an oral live attenuated human rotavirus vaccine against rotavirus gastroenteritis during the first 2 years of life in Latin American infants: a randomised, double-blind, placebo-controlled phase III study. Lancet. 2008; 371: 1181–1189.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Vesikari T. et al. Efficacy of human rotavirus vaccine against rotavirus gastroenteritis during the first 2 years of life in European infants: randomised, double-blind controlled study. Lancet. 2007; 24 (370): 1757–1763.</mixed-citation><mixed-citation xml:lang="en">Vesikari T. et al. Efficacy of human rotavirus vaccine against rotavirus gastroenteritis during the first 2 years of life in European infants: randomised, double-blind controlled study. Lancet. 2007; 24 (370): 1757–1763.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Phua K.B. et al. Rotavirus vaccine RIX4414 efficacy sustained during the third year of life: a randomized clinical trial in an Asian population. Vaccine. 2012; 30: 4552–4557.</mixed-citation><mixed-citation xml:lang="en">Phua K.B. et al. Rotavirus vaccine RIX4414 efficacy sustained during the third year of life: a randomized clinical trial in an Asian population. Vaccine. 2012; 30: 4552–4557.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Armah G.E. et al. Efficacy of pentavalent rotavirus vaccine against severe rotavirus gastroenteritis in infants in developing countries in sub-Saharan Africa: a randomised, double-blind, placebo-controlled trial. Lancet. 2010; 376:606–614.</mixed-citation><mixed-citation xml:lang="en">Armah G.E. et al. Efficacy of pentavalent rotavirus vaccine against severe rotavirus gastroenteritis in infants in developing countries in sub-Saharan Africa: a randomised, double-blind, placebo-controlled trial. Lancet. 2010; 376:606–614.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Madhi S.A. et al. Efficacy and immunogenicity of 2 or 3 dose rotavirus-vaccine regimen in South African children over two consecutive rotavirus-seasons: a randomized, double-blind, placebo-controlled trial. Vaccine. 2012; 30 (Suppl. 1): A44–51.</mixed-citation><mixed-citation xml:lang="en">Madhi S.A. et al. Efficacy and immunogenicity of 2 or 3 dose rotavirus-vaccine regimen in South African children over two consecutive rotavirus-seasons: a randomized, double-blind, placebo-controlled trial. Vaccine. 2012; 30 (Suppl. 1): A44–51.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Madhi S.A. et al. Effect of human rotavirus vaccine on severe diarrhoea in African infants. New England Journal of Medicine. 2010; 362: 289–298.</mixed-citation><mixed-citation xml:lang="en">Madhi S.A. et al. Effect of human rotavirus vaccine on severe diarrhoea in African infants. New England Journal of Medicine. 2010; 362: 289–298.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Grading of scientific evidence — Tables 5–6: Is giving a third dose of RV1 superior to the currently recommended 2-dose schedule? (Table 5); Is partial vaccination also efficacious against severe rotavirus diarrhoea? (Table 6). Available from http://www.who.int/immunization/position_papers/rotavirus_grad_rv1_3rd_dose</mixed-citation><mixed-citation xml:lang="en">Grading of scientific evidence — Tables 5–6: Is giving a third dose of RV1 superior to the currently recommended 2-dose schedule? (Table 5); Is partial vaccination also efficacious against severe rotavirus diarrhoea? (Table 6). Available from http://www.who.int/immunization/position_papers/rotavirus_grad_rv1_3rd_dose</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Steele A.D. et al. Safety, reactogenicity, and immunogenicity of human rotavirus vaccine RIX4414 in human immunodeficiency virus-positive infants in South Africa. Pediatric Infectious Disease Journal. 2011; 30: 125–130.</mixed-citation><mixed-citation xml:lang="en">Steele A.D. et al. Safety, reactogenicity, and immunogenicity of human rotavirus vaccine RIX4414 in human immunodeficiency virus-positive infants in South Africa. Pediatric Infectious Disease Journal. 2011; 30: 125–130.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Laserson K.F. et al. Safety of the pentavalent rotavirus vaccine (PRV), RotaTeq (®), in Kenya, including among HIV-infected and HIVexposed infants. Vaccine. 2012; 30 Suppl 1: A61–70.</mixed-citation><mixed-citation xml:lang="en">Laserson K.F. et al. Safety of the pentavalent rotavirus vaccine (PRV), RotaTeq (®), in Kenya, including among HIV-infected and HIVexposed infants. Vaccine. 2012; 30 Suppl 1: A61–70.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">See http://us.gsk.com/products/assets/us_rotarix.pdf</mixed-citation><mixed-citation xml:lang="en">See http://us.gsk.com/products/assets/us_rotarix.pdf</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">See http://www.merck.com/product/usa/pi_circulars/r/rotateq/rotateq_pi.pdf</mixed-citation><mixed-citation xml:lang="en">See http://www.merck.com/product/usa/pi_circulars/r/rotateq/rotateq_pi.pdf</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Soares-Weiser K. et al. Rotavirus vaccine schedules: a systematic review of safety and efficacy from RCTs and observational studies of childhood schedules using RV1 and RV5 vaccines. Report to WHO/Initiative for Vaccine Research, 2012. Available from http://www.who.int/immunization/sage/meetings/2012/april/Soares_K_et_al._SAGE_April_rotavirus.pdf, accessed January 2013.</mixed-citation><mixed-citation xml:lang="en">Soares-Weiser K. et al. Rotavirus vaccine schedules: a systematic review of safety and efficacy from RCTs and observational studies of childhood schedules using RV1 and RV5 vaccines. Report to WHO/Initiative for Vaccine Research, 2012. Available from http://www.who.int/immunization/sage/meetings/2012/april/Soares_K_et_al._SAGE_April_rotavirus.pdf, accessed January 2013.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Goveia M.G. et al. Efficacy of pentavalent human-bovine (WC3) reassortant rotavirus vaccine based on breastfeeding frequency. The Pediatric Infectious Disease Journal. 2008; 27: 656–658.</mixed-citation><mixed-citation xml:lang="en">Goveia M.G. et al. Efficacy of pentavalent human-bovine (WC3) reassortant rotavirus vaccine based on breastfeeding frequency. The Pediatric Infectious Disease Journal. 2008; 27: 656–658.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">McClenahan S.D. et al. Molecular and infectivity studies of porcine circovirus in vaccines. Vaccine. 2011; 29: 4745–4753.</mixed-citation><mixed-citation xml:lang="en">McClenahan S.D. et al. Molecular and infectivity studies of porcine circovirus in vaccines. Vaccine. 2011; 29: 4745–4753.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Global illness and deaths caused by rotavirus disease in children. Emerging Infectious Diseases. 2010; 30: 285–292.</mixed-citation><mixed-citation xml:lang="en">Global illness and deaths caused by rotavirus disease in children. Emerging Infectious Diseases. 2010; 30: 285–292.</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Acute intussusception in infants and young children (WHO/ V&amp;B/.02.19). Geneva, World Health Organization. 2002. Available at http://www.who.int/vaccinesdocuments/DocsPDF06/www640.pdf, accessed January 2013.</mixed-citation><mixed-citation xml:lang="en">Acute intussusception in infants and young children (WHO/ V&amp;B/.02.19). Geneva, World Health Organization. 2002. Available at http://www.who.int/vaccinesdocuments/DocsPDF06/www640.pdf, accessed January 2013.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Buttery J.P. et al. Intussusception following rotavirus vaccine administration: postmarketing surveillance in the National Immunization Program in Australia. Vaccine. 2011; 29: 3061–3066.</mixed-citation><mixed-citation xml:lang="en">Buttery J.P. et al. Intussusception following rotavirus vaccine administration: postmarketing surveillance in the National Immunization Program in Australia. Vaccine. 2011; 29: 3061–3066.</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Ruiz-Palacios G.M. et al. Safety and efficacy of an attenuated vaccine against severe rotavirus gastroenteritis. New England Journal of Medicine. 2006; 354: 11–22.</mixed-citation><mixed-citation xml:lang="en">Ruiz-Palacios G.M. et al. Safety and efficacy of an attenuated vaccine against severe rotavirus gastroenteritis. New England Journal of Medicine. 2006; 354: 11–22.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Patel M.M. et al. Intussusception risk and health benefits of rotavirus vaccination in Mexico and Brazil. New England Journal of Medicine. 2011; 364: 2283–2292.</mixed-citation><mixed-citation xml:lang="en">Patel M.M. et al. Intussusception risk and health benefits of rotavirus vaccination in Mexico and Brazil. New England Journal of Medicine. 2011; 364: 2283–2292.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Velazquez F.R. et al. Postmarketing Surveillance of Intussusception Following Mass Introduction of the monovalent human Rotavirus Vaccine in Mexico_(UGG)_(EPI PLAN). The</mixed-citation><mixed-citation xml:lang="en">Velazquez F.R. et al. Postmarketing Surveillance of Intussusception Following Mass Introduction of the monovalent human Rotavirus Vaccine in Mexico_(UGG)_(EPI PLAN). The</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Pediatric Infectious Disease Journal. 2012; 31: 736–744.</mixed-citation><mixed-citation xml:lang="en">Pediatric Infectious Disease Journal. 2012; 31: 736–744.</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Shui I.M. et al. Risk of intussusception following administration of a pentavalent rotavirus vaccine in US infants. JAMA: the Journal of the American Medical Association. 2012; 307: 598–604.</mixed-citation><mixed-citation xml:lang="en">Shui I.M. et al. Risk of intussusception following administration of a pentavalent rotavirus vaccine in US infants. JAMA: the Journal of the American Medical Association. 2012; 307: 598–604.</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Loughlin J. et al. Postmarketing evaluation of the short-term safety of the pentavalent rotavirus vaccine. The Pediatric Infectious Disease Journal. 2012; 31: 292–296.</mixed-citation><mixed-citation xml:lang="en">Loughlin J. et al. Postmarketing evaluation of the short-term safety of the pentavalent rotavirus vaccine. The Pediatric Infectious Disease Journal. 2012; 31: 292–296.</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Weekly Epidemiological Record. 2012; 6: 53–60. URL: http://www.who.int/wer</mixed-citation><mixed-citation xml:lang="en">Weekly Epidemiological Record. 2012; 6: 53–60. URL: http://www.who.int/wer</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Grade table 7: Is it safe to administer the first dose of vaccine at different ages? Available from http://www.who.int/immunization/position_papers/rotavirus_grad_safe_first_dose_ages</mixed-citation><mixed-citation xml:lang="en">Grade table 7: Is it safe to administer the first dose of vaccine at different ages? Available from http://www.who.int/immunization/position_papers/rotavirus_grad_safe_first_dose_ages</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Cherian T. et al. Rotavirus vaccines in developing countries: the potential impact, implementation challenges, and remaining questions. Vaccine. 2012; 30 (Suppl. 1): A3–6.</mixed-citation><mixed-citation xml:lang="en">Cherian T. et al. Rotavirus vaccines in developing countries: the potential impact, implementation challenges, and remaining questions. Vaccine. 2012; 30 (Suppl. 1): A3–6.</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">van Hoek A.J. et al. (2012) A cost effectiveness and capacity analysis for the introduction of universal rotavirus vaccination in Kenya: Comparison between Rotarix and RotaTeq Vaccines. PLoS ONE. 2012; 7: e47511.</mixed-citation><mixed-citation xml:lang="en">van Hoek A.J. et al. (2012) A cost effectiveness and capacity analysis for the introduction of universal rotavirus vaccination in Kenya: Comparison between Rotarix and RotaTeq Vaccines. PLoS ONE. 2012; 7: e47511.</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Postma M.J. et al. Comparative review of 3 cost-effectiveness models for rotavirus vaccines in national immunization programs; a generic approach applied to various regions in the world. BMC Medicine. 2011; 9: 84.</mixed-citation><mixed-citation xml:lang="en">Postma M.J. et al. Comparative review of 3 cost-effectiveness models for rotavirus vaccines in national immunization programs; a generic approach applied to various regions in the world. BMC Medicine. 2011; 9: 84.</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Diarrhoea: why children are still dying and what can be done. Geneva, WHO/UNICEF. 2009. Available from http://www.who.int/maternal_child_adolescent/documents/9789241598415/en/index.html, accessed January 2013.</mixed-citation><mixed-citation xml:lang="en">Diarrhoea: why children are still dying and what can be done. Geneva, WHO/UNICEF. 2009. Available from http://www.who.int/maternal_child_adolescent/documents/9789241598415/en/index.html, accessed January 2013.</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">Pneumonia and diarrhoea: tackling the deadliest diseases for the world’s poorest children. New York, UNICEF. 2012. Available from http://www.unicef.org/media/files/UNICEF_P_D_complete_0604.pdf, accessed January 2013.</mixed-citation><mixed-citation xml:lang="en">Pneumonia and diarrhoea: tackling the deadliest diseases for the world’s poorest children. New York, UNICEF. 2012. Available from http://www.unicef.org/media/files/UNICEF_P_D_complete_0604.pdf, accessed January 2013.</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Weekly Epidemiological Record. 2011; 8: 61–72. URL: http://www.who.int/wer</mixed-citation><mixed-citation xml:lang="en">Weekly Epidemiological Record. 2011; 8: 61–72. URL: http://www.who.int/wer</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
