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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ppharm</journal-id><journal-title-group><journal-title xml:lang="ru">Педиатрическая фармакология</journal-title><trans-title-group xml:lang="en"><trans-title>Pediatric pharmacology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-5776</issn><issn pub-type="epub">2500-3089</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/pf.v18i1.2286</article-id><article-id custom-type="elpub" pub-id-type="custom">ppharm-2023</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ РЕКОМЕНДАЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL RECOMMENDATIONS</subject></subj-group></article-categories><title-group><article-title>Современные принципы ведения детей с пищевой аллергией</article-title><trans-title-group xml:lang="en"><trans-title>Modern Principles of Managing Children with Food Allergies</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3987-8112</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баранов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Baranov</surname><given-names>Alexander A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Баранов Александр Александрович - доктор медицинских наук, профессор, академик Российской академии наук; eLibrary SPIN: 3570-1806.</p><p>119333, Москва, ул. Фотиевой, д. 10, телефон: 8 (499) 400-47-33</p></bio><bio xml:lang="en"><p>MD, PhD, Professor, Academician of the RAS; eLibrary SPIN: 3570-1806</p><p>10 Fotievoy street, 119333, Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2209-7531</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Намазова-Баранова</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Namazova-Baranova</surname><given-names>Leyla S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Намазова-Баранова Лейла Сеймуровна - доктор медицинских наук, профессор, академик Российской академии наук; eLibrary SPIN: 1312-2147.</p><p>119333, Москва, ул. Фотиевой, д. 10; телефон: 8 (499) 400-47-33</p></bio><bio xml:lang="en"><p>Leyla S. Namazova-Baranova, MD, PhD, Professor, Academician of the RAS; eLibrary SPIN: 1312-2147.</p><p>10 Fotievoy street, 119333, Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3064-8871</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хаитов</surname><given-names>Р. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Khaitov</surname><given-names>Rakhim M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хаитов Рахим Мусаевич - доктор медицинских наук, профессор, академик Российской академии наук; AuthorID: 108140.</p><p>115522, Москва, Каширское шоссе, д. 24; телефон: 8 (499) 311-67-78</p></bio><bio xml:lang="en"><p>MD, PhD, Professor, Academician of tho RAS; AuthorID: 108140</p><p>24 Kashirskoe highway, 115522, Moscow</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3556-969X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ильина</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Il'ina</surname><given-names>Natalia I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ильина Наталья Ивановна - доктор медицинских наук, профессор; eLibrary SPIN: 5535-1246</p><p>115522, Москва, Каширское шоссе, д. 24; телефон: 8 (499) 617-08-00</p></bio><bio xml:lang="en"><p>MD, PhD, Professor; eLibrary SPIN: 5535-1246</p><p>24 Kashirskoe highway, 115522, Moscow</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3250-0694</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Курбачева</surname><given-names>О. 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П.</given-names></name><name name-style="western" xml:lang="en"><surname>Kovtun</surname><given-names>Olga P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ковтун Ольга Петровна - доктор медицинских наук, профессор, член-корреспондент Российской академии наук; eLibrary SPIN: 9919-9048.</p><p>620028, Екатеринбург, ул. Репина, д. 3; телефон: 8 (343) 214 86 52</p></bio><bio xml:lang="en"><p>MD, PhD, Professor, Corresponding Member of the RAS; eLibrary SPIN: 9919-9048.</p><p>3 Repina street, 620028, Ekaterinburg</p></bio><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7571-5460</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Новик</surname><given-names>Г. 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Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Selimzyanova</surname><given-names>Lilia R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Селимзянова Лилия Робертовна - кандидат медицинских наук; eLibrary SPIN: 5508-1689.</p><p>119333, Москва, ул. Фотиевой, д. 10; телефон: 8 (499) 400-47-33</p></bio><bio xml:lang="en"><p>MD, PhD; eLibrary SPIN: 5508-1689</p><p>119333, Москва, ул. Фотиевой, д. 10; телефон: 8 (499) 400-47-33</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3598-9600</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чемакина</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Chemakina</surname><given-names>Daria S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чемакина Дарья Сергеевна - кандидат медицинских наук; eLibrary SPIN: 9275-6539.</p><p>119333, Москва, ул. Фотиевой, д. 10; телефон: 8 (499) 400-47-33</p></bio><bio xml:lang="en"><p>MD, PhD; eLibrary SPIN: 9275-6539.</p><p>10 Fotievoy street, 119333, Moscow</p></bio><xref ref-type="aff" rid="aff-9"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8023-2543</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеева</surname><given-names>А. 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Фотиевой, д. 10</p></bio><bio xml:lang="en"><p>MD, PhD; eLibrary SPIN: 4626-2800</p><p>10 Fotievoy street, 119333, Moscow</p></bio><xref ref-type="aff" rid="aff-10"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0317-2425</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Эфендиева</surname><given-names>К. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Efendieva</surname><given-names>Kamilla E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Эфендиева Камилла Евгеньевна - кандидат медицинских наук; eLibrary SPIN: 5773-3901.</p><p>119333, Москва, ул. Фотиевой, д. 10; телефон: 8 (499) 400-47-33</p></bio><bio xml:lang="en"><p>MD, PhD; eLibrary SPIN: 5773-3901.</p><p>10 Fotievoy street, 119333, Moscow</p></bio><xref ref-type="aff" rid="aff-8"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3696-3293</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Добрынина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Dobrynina</surname><given-names>Elena A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Добрынина Елена Андреевна; eLibrary SPIN: 1598-5263.</p><p>119333, Москва, ул. Фотиевой, д. 10; телефон: 8 (499) 400-47-33</p></bio><bio xml:lang="en"><p>eLibrary SPIN: 1598-5263</p><p>10 Fotievoy street, 119333, Moscow</p></bio><xref ref-type="aff" rid="aff-11"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4680-2925</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Привалова</surname><given-names>Т. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Privalova</surname><given-names>Tatyana E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Привалова Татьяна Евгеньевна, кандидат медицинских наук; eLibrary SPIN: 7879-4299.</p><p>119333, Москва, ул. Фотиевой, д. 10; телефон: 8 (499) 400-47-33</p></bio><bio xml:lang="en"><p>MD, PhD; eLibrary SPIN: 7879-4299</p><p>10 Fotievoy street, 119333, Moscow</p></bio><xref ref-type="aff" rid="aff-8"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5263-6743</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сновская</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Snovskaya</surname><given-names>Marina A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сновская Марина Андреевнат - кандидат медицинских наук; eLibrary SPIN: 9899-109.</p><p>119991, Москва, Ломоносовский пр-т, д. 2, стр. 1</p></bio><bio xml:lang="en"><p>MD, PhD; eLibrary SPIN: 9899-109</p><p>119991, Москва, Ломоносовский пр-т, д. 2, стр. 1</p></bio><xref ref-type="aff" rid="aff-7"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">НИИ педиатрии и охраны здоровья детей ЦКБ РАН Министерства науки и высшего образования РФ; Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет), Москва, Российская Федерация<country>Россия</country></aff><aff xml:lang="en">Research Institute of Pediatrics and Children's Health in Central Clinical Hospital of the Russian Academy of Sciences; Sechenov First Moscow State Medical University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">НИИ педиатрии и охраны здоровья детей ЦКБ РАН Министерства науки и высшего образования РФ; Российский национальный исследовательский медицинский университет им. Н.И. Пирогова; Белгородский государственный национальный исследовательский университет<country>Россия</country></aff><aff xml:lang="en">Research Institute of Pediatrics and Children's Health in Central Clinical Hospital of the Russian Academy of Sciences; Pirogov Russian National Research Medical University; Belgorod National Research University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">Государственный научный центр Институт иммунологии<country>Россия</country></aff><aff xml:lang="en">State Scientific Center Institute of Immunology<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru">Российский национальный исследовательский медицинский университет им. Н.И. Пирогова; Государственный научный центр Институт иммунологии<country>Россия</country></aff><aff xml:lang="en">Pirogov Russian National Research Medical University; State Scientific Center Institute of Immunology<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru">Уральский государственный медицинский университет<country>Россия</country></aff><aff xml:lang="en">Ural State Medical University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru">Санкт-Петербургский государственный педиатрический медицинский университет<country>Россия</country></aff><aff xml:lang="en">Saint Petersburg State Pediatric Medical University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-7"><aff xml:lang="ru">Национальный медицинский исследовательский центр здоровья детей<country>Россия</country></aff><aff xml:lang="en">National Medical Research Center of Children's Health<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-8"><aff xml:lang="ru">НИИ педиатрии и охраны здоровья детей ЦКБ РАН Министерства науки и высшего образования РФ; Российский национальный исследовательский медицинский университет им. Н.И. Пирогова<country>Россия</country></aff><aff xml:lang="en">Research Institute of Pediatrics and Children's Health in Central Clinical Hospital of the Russian Academy of Sciences; Pirogov Russian National Research Medical University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-9"><aff xml:lang="ru">НИИ педиатрии и охраны здоровья детей ЦКБ РАН Министерства науки и высшего образования РФ<country>Россия</country></aff><aff xml:lang="en">Research Institute of Pediatrics and Children's Health in Central Clinical Hospital of the Russian Academy of Sciences<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-10"><aff xml:lang="ru">НИИ педиатрии и охраны здоровья детей ЦКБ РАН Министерства науки и высшего образования РФ; Российский национальный исследовательский медицинский университет им. Н.И. Пирогова<country>Россия</country></aff><aff xml:lang="en">Research Institute of Pediatrics and Children's Health in Central Clinical Hospital of the Russian Academy of Sciences<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-11"><aff xml:lang="ru">Союз педиатров России<country>Россия</country></aff><aff xml:lang="en">The Union of pediatricians of Russia<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>30</day><month>07</month><year>2021</year></pub-date><volume>18</volume><issue>3</issue><fpage>245</fpage><lpage>263</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Баранов А.А., Намазова-Баранова Л.С., Хаитов Р.М., Ильина Н.И., Курбачева О.М., Ковтун О.П., Новик Г.А., Макарова С.Г., Вишнёва Е.А., Селимзянова Л.Р., Чемакина Д.С., Алексеева А.А., Левина Ю.Г., Эфендиева К.Е., Добрынина Е.А., Привалова Т.Е., Сновская М.А., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Баранов А.А., Намазова-Баранова Л.С., Хаитов Р.М., Ильина Н.И., Курбачева О.М., Ковтун О.П., Новик Г.А., Макарова С.Г., Вишнёва Е.А., Селимзянова Л.Р., Чемакина Д.С., Алексеева А.А., Левина Ю.Г., Эфендиева К.Е., Добрынина Е.А., Привалова Т.Е., Сновская М.А.</copyright-holder><copyright-holder xml:lang="en">Baranov A.A., Namazova-Baranova L.S., Khaitov R.M., Il'ina N.I., Kurbacheva O.M., Kovtun O.P., Novik G.A., Makarova S.G., Vishneva E.A., Selimzyanova L.R., Chemakina D.S., Alexeeva A.A., Levina Y.G., Efendieva K.E., Dobrynina E.A., Privalova T.E., Snovskaya M.A.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pedpharma.ru/jour/article/view/2023">https://www.pedpharma.ru/jour/article/view/2023</self-uri><abstract><p>В статье представлены современные сведения об эпидемиологии, этиологии и клинических проявлениях аллергических реакций на продукты питания у детей. Освещены основанные на доказательной медицине подходы к диагностике, в том числе дифференциальной, лечению и профилактике пищевой аллергии у детей. Подробно изложены тактика и алгоритмы ведения пациентов. Рекомендации разработаны на основании всех доступных на сегодняшний день данных по пищевой аллергии. Материал основан на методическом руководстве по ведению пациентов с пищевой аллергией, ранее разработанном экспертами-специалистами Союза педиатров России в 2021 г.</p></abstract><trans-abstract xml:lang="en"><p>The article presents modern data on the epidemiology, etiology and clinical manifestations of food allergies in children. Evidence-based approaches to diagnosis, including differential, treatment, and prevention of food allergies in children are shown. Patient management tactics and algorithms are presented in detail. The guidelines are based on all available up-to-date data on food allergies. The material is based on the methodological guideline for the management of patients with food allergies previously developed by expert specialists of the Union of Pediatricians of Russia in 2021.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>пищевая аллергия</kwd><kwd>IgE-опосредованные реакции</kwd><kwd>не-IgE-опосредованные реакции</kwd><kwd>сенсибилизация</kwd><kwd>пищевые аллергены</kwd><kwd>белок коровьего молока</kwd></kwd-group><kwd-group xml:lang="en"><kwd>food allergy</kwd><kwd>IgE-directed response</kwd><kwd>non-IgE-directed response</kwd><kwd>sensitization</kwd><kwd>food allergens</kwd><kwd>cow milk protein</kwd></kwd-group><funding-group xml:lang="ru"><funding-statement>Не указан</funding-statement></funding-group><funding-group xml:lang="en"><funding-statement>Not specified</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Намазова-Баранова Л. 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