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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ppharm</journal-id><journal-title-group><journal-title xml:lang="ru">Педиатрическая фармакология</journal-title><trans-title-group xml:lang="en"><trans-title>Pediatric pharmacology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-5776</issn><issn pub-type="epub">2500-3089</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/pf.v12i2/1276</article-id><article-id custom-type="elpub" pub-id-type="custom">ppharm-2</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>СОСТОЯНИЕ ФУНКЦИИ ВНЕШНЕГО ДЫХАНИЯ И ДЫХАТЕЛЬНОЙ МУСКУЛАТУРЫ У ДЕТЕЙ С ОЖИРЕНИЕМ</article-title><trans-title-group xml:lang="en"><trans-title>LUNG FUNCTION AND RESPIRATORY MUSCLE STRENGTH IN OBESE IN CHILDREN</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фурман</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Furman</surname><given-names>E. G.</given-names></name></name-alternatives><email xlink:type="simple">furman1@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ярулина</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Yarulina</surname><given-names>A. M.</given-names></name></name-alternatives><email xlink:type="simple">furman1@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Софронова</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sofronova</surname><given-names>L. V.</given-names></name></name-alternatives><email xlink:type="simple">furman1@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Пермский государственный медицинский университет имени академика Е.А. Вагнера, Российская Федерация</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Perm State Medical University named after Academician E.A. Wagner, Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Городская детская клиническая поликлиника № 2, Пермь, Российская Федерация</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City children's clinical hospital № 2, Perm, Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>01</day><month>03</month><year>2015</year></pub-date><volume>12</volume><issue>2</issue><issue-title>Педиатрическая фармакология</issue-title><fpage>143</fpage><lpage>147</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Фурман Е.Г., Ярулина А.М., Софронова Л.В., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Фурман Е.Г., Ярулина А.М., Софронова Л.В.</copyright-holder><copyright-holder xml:lang="en">Furman E.G., Yarulina A.M., Sofronova L.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pedpharma.ru/jour/article/view/2">https://www.pedpharma.ru/jour/article/view/2</self-uri><abstract><sec><title>Обоснование</title><p>Обоснование. Доказаны факты разностороннего воздействия ожирения на состояние функции внешнего дыхания и взаимосвязь с рядом заболеваний дыхательной системы. Ожирение само по себе, даже при отсутствии других известных причин, может вызывать ощущение одышки в состоянии покоя. В то же время одышка является и кардинальным симптомом респираторной мышечной слабости , снижая толерантность к физическим нагрузкам. В современной медицине состояние функции внешнего дыхания и дыхательной мускулатуры у детей с различной степенью ожирения ― проблема актуальная и недостаточно изученная. Цель исследования: оценить состояние вентиляционной функции и силы дыхательной мускулатуры у детей с ожирением. Методы. Обследовано 46 детей в возрасте от 7 до 16 лет с ожирением. Оценивали спирограмму и силу респираторной мускулатуры в виде максимального инспираторного давления на уровне ротовой полости (MIP), максимального экспираторного давления на уровне ротовой полости (MЕP) и назального инспираторного давления в тесте на дыхание (sniff-тест, SNIP). Результаты. У детей с ожирением при наличии жалоб на одышку отмечалась дисфункция дыхательной мускулатуры. Снижение силы дыхательной мускулатуры (≤ 80% от норматива) наблюдалось у 44% обследованных по показателю MIP и 38% ― по MEP. Повышенный индекс массы тела свидетельствовал об увеличении силы дыхательной мускулатуры. Выводы. Мониторинг состояния функции внешнего дыхания и оценка силы дыхательной мускулатуры способствуют раннему выявлению нарушений функции дыхательной системы у детей с ожирением.</p></sec><sec><title> </title><p> </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. It is known that obesity may influence the state of respiratory function and it is associated with a number of diseases of the respiratory system. Obesity in itself, even in the absence of other known causes, can cause a feeling of shortness of breath at rest. At the same time, the cardinal symptom of respiratory muscle weakness is shortness of breath, which promotes the reduction of exercise tolerance. At the moment the problem state of respiratory function and respiratory muscles in children with different degrees of obesity is relevant and understudied. Aim. Investigation of lung function and respiratory muscle strength in obese in children. Methods. 46 children with obesity were examined, with a prevalence of obesity of mixed origin with progressive, aged 7 to 16 years. We evaluated the lung function and strength of respiratory muscles in the form of maximum inspiratory pressure at the mouth (MIP), maximal expiratory pressure at the mouth (MEP) and nasal inspiratory pressure in the sniff-test (SNIP). Results. The children with obesity complained of dyspnea. The respiratory muscle dysfunction observed in the form of reduction of its forces. Reduced respiratory muscle strength ( 80% of the norm) was in 44% of patients on the MIP and 38% on the MEP and was increased with increasing body mass index. Conclusion. Children with obesity need to monitor the lung function and evaluate the strength of the respiratory muscles for early detection of functional disorders of the respiratory system.</p></sec><sec><title> </title><p> </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>детиж ожирениеж состояние вентиляционной функцииж сила дыхательной мускулатуры</kwd></kwd-group><kwd-group xml:lang="en"><kwd>childrenж obesit</kwd><kwd>lung function assessment</kwd><kwd>respiratory muscle strength</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Deckelbaum R. J., Williams C. L. Childhoodobesity: the health issue. Obes Res. 2001; 9 (Suppl. 4): 239–243.</mixed-citation><mixed-citation xml:lang="en">Deckelbaum R.J., Williams C.L. Childhoodobesity: the health issue. 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